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All Journal Majalah Kedokteran Bandung Althea Medical Journal Global Medical and Health Communication Jurnal Media Gizi Indonesia (MGI) Molecular and Cellular Biomedical Sciences (MCBS) AcTion: Aceh Nutrition Journal Jurnal Gizi Klinik Indonesia Jurnal Pendidikan dan Pelayanan Kebidanan Indonesia (Indonesian Journal of Education and Midwifery Care) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Jurnal Health Sains Jurnal Ilmu Faal Olahraga Indonesia
Gaga Irawan Nugraha
Fakultas Kedokteran Universitas Padjadjaran
Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Journal : Jurnal Media Gizi Indonesia (MGI)

 1 
DIETARY INTAKE AND SUN EXPOSURE RELATED TO VITAMIN D CONCENTRATION IN THALASSEMIA PATIENTS: A LITERATURE REVIEW Yesi Herawati; Gaga Irawan Nugraha; Dida Akhmad Gurnida
Media Gizi Indonesia Vol. 16 No. 3 (2021): JURNAL MEDIA GIZI INDONESIA (NATIONAL NUTITRION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v16i3.238-247

Abstract

Vitamin D has an important role in calcium homeostasis and bone minerals during rapid growth periods. Several studies have shown that deficiency of vitamin D occurs in thalassemia patient. The study used literature review to determine relation of dietary intake and sun exposure with vitamin D concentration in thalassemia patiens in 29 literatures. Those literatures were taken from books and articles published from 2010 to 2019 with the keywords “thalassemia”, “dietary intake”, “sun exposure” and “vitamin D” using database in Pubmed, Google Scholar and Medline. The results of 29 literatures showed that vitamin D deficiency is caused by reduced dietary intake and impaired vitamin D hydroxylation in the liver due to hemochromatosis resulting in high serum ferritin. Source of vitamin D comes from endogenous synthesis with sunlight exposure and little dietary source of vitamin D2 and vitamin D3. Another food intake can also affect serum vitamin D concentration, mainly fat and protein intake. Vitamin D is fat soluble vitamin, it can    be stored in the fat for later metabolized in the liver. Protein is required to transport vitamin D to blood circulation, enzyme formation and vitamin D receptor (VDR). Thalassemia patients need to increase of macro and micronutrients requirement. Low Hb concentration causes fatigue, tired easily and decreased appetite. A lot of research on thalassemia children found that intake of energy and protein were lower than recommended and lack of sun exposure. These conditions will affect to vitamin D concentration. A comprehensive understanding in the relationship of dietary intake and sun exposure to vitamin D concentration in thalassemia patients is explained in this mini review. Maintaining normal vitamin D concentration through adequate dietary intake and sun exposure are very important to optimize growth in thalassemia patients.
Co-Authors - Yusnita, - Achadiyani Ambrosius Purba Ambrosius Purba Armijn Firman Armijn Firman, Armijn Bellia Loranthifolia Martasari Budi Setiabudiawan Cafrina, Gabriella Cahyadi, Wisnu Dany Hilmanto Dewi, Ni Wayan Eka Rahayu Dida Akhmad Gurnida Dida Akhmad Gurnida Dwi Agustian Elissa Evanti Widjaja Farid Husin Farid Husin Firman Fuad Wirakusumah Gabriella Cafrina Gloria Kartika Gurid PE Mulyo Henni Djuhaeni Hikmat Permana Hikmat Permana I Made Jawi Irma Ruslina Defi Kartika, Gloria Kasmanto, Hendro Kavita Arumugam Kavita Arumugam, Kavita Kusnandi Rusmil Kusnandi Rusmil Lasiyati Yuswo Yani Lisda Amalia Lola Ilona Lukman Pura Lynna Lidyana Lynna Lidyana Mieke Hemiawati Satari Monita Sugianto Oki Suwarsa Rachmat Soelaeman Rezah Andriani Ria Bandiara Rudi Supriyadi Sefti Atletika Asiani Sefti Atletika Asiani Seni Rahayu Setiawan Setiawan Siti Nur Fatimah Siti Nur Fatimah Sri Hartini K. S. Kariadi Stephanus Kristianto Witono Sudigdo Adi Sunarjati Sudidgo Adi Sunarjati Sudigdoadi Sunarjati Sudigdoadi Sunarjati Sudigdoadi Susiarno, Hadi Tiara Aulia Maisyarah Tiara Aulia Maisyarah Titing Nurhayati Vita Murniati Tarawan Vitriana Vitriana Yenni Zuhairini Yesi Herawati Yudi Mulyana Hidayat Zulmansyah , Zulmansyah