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Sumaryati Syukur
Universitas Andalas
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Journal : Journal of Dentomaxillofacial Science

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Analysis of gene polymorphisms TGF? rs 1058213 to cleft lip cases with or without a non-syndrome cleft palate in Riau Malay Ethnic Masrial Masrial; Yanwirasti Yanwirasti; Sumaryati Syukur; Endang Syamsudin
Journal of Dentomaxillofacial Science Vol. 3 No. 1 (2018): (Available online: 1 April 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v3i1.498

Abstract

Objective: This study aims to determine the role of gene polymorphism TGFα rs 1058213 in cases of cleft lip with or without cleft palate nonsyndrome in the Riau Malay tribe.Material and Methods: DNA extraction of venous blood and polymorphism TGFα rs 1058213 was assessed using the Restriction Fragment Length Polymorphism-PCR (RFLP-PCR) working method and followed by sequencing. Genotyping SNP rs1058213 in the TGFα gene was performed by the RFLP-PCR method in control and CLP NS patients. The data was assessed using the test statistic premises T-test difference test.Results: The total sample size included 68 samples consisting of 34 CLP NS samples and 34 control samples. The cases of CLP NS occurred more in men than women, 20 cases (59%) and 14 cases (14%), respectively.Conclusion: There was no significant difference between TGFα rs 1058213 gene polymorphisms in CLP NS and controls in the Riau Malay tribe.
Co-Authors -, Risfaheri -, Urnemi -, Vovien -, Wiranda Abdi Dharma Allimuddin Tofrizal Armaini - Asmar Yulastri Azhar, Minda Bisping Bernward Bramadi Arya Dahlyanti, Rina Desmiwarti Desmiwarti DESSY NATALIA Endang Purwati RN Endang Syamsudin fahmi, Aliyah - Femilya Putri Ferdinal Ferry Fivi Mona Bareno Helmi Arifin Hermansyah Aziz Hermansyah Aziz Hevi Horiza Hidayat, Zoni Imelda Imelda Jamsari Jamsari Lidya Sari Utami Linda Rosalina Maliza, Rita Masrial Masrial Melia, Sri Minda Azhar Murni, Yulia Nanda Tri Wahdini Natalia, Dessy Norman Ferdinal Novesar Jamarun Novesar Jamarun Putri Zelfitri Zen Rahmiana Zein Refilda Refilda Refinel - Rina Dahlyanti Risfaheri - Risma Sari Safni Safni Sanusi Ibrahim Sartika, Diza Sumanti, Titi Suryati Suryati Syukri Arief Titi Sumanti Tommi Hermansyah Urnemi - Urnemi Urnemi Vovien - Wardi, Epi Supri Wiranda - Yanwirasti Yanwirasti Yefrida Yefrida Yetria Rilda Yulia Murni Yulizar Yusuf Zilfa Zilfa ZK Abdurahman Baizal Zona Octarya Zona Octarya Zoni Hidayat Zozy Aneloi Noli Zulkarnain Chaidir Zulkarnain Khaidir