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All Journal Jurnal Ilmiah Farmasi Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Pharmaciana: Jurnal Kefarmasian Jurnal Farmasi Andalas Jurnal Sains dan Teknologi Farmasi Jurnal Riset Kimia INDONESIAN JOURNAL OF PHARMACY Science and Technology Indonesia JOPS (Journal Of Pharmacy and Science) JSFK (Jurnal Sains Farmasi & Klinis) JFIOnline JURNAL ILMU KEFARMASIAN INDONESIA Jurnal Farmasi Higea Majalah Farmasetika Medical Sains : Jurnal Ilmiah Kefarmasian
Erizal Zaini
Departemen Farmasetik, Fakultas Farmasi, Universitas Andalas, Padang 25163
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health

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Journal : Jurnal Farmasi Andalas

 1 
Kajian Biodegradasi Filem Plastik Campuran Polistiren dengan Poli(3hidroksibutirat-ko-3-hidroksivalerat) dalam Tanah Secara In-vitro Permatadewi, Asiska; Zaini, Erizal; Rustini, Rustini; Djamaan, Akmal
Jurnal Farmasi Andalas Vol 1, No 1 (2013)
Publisher : Jurnal Farmasi Andalas

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Abstract

The in vitro biodegradation testing of plastic of the mixture of polystyrene (PS) and poly (3-hydroxybutirate-co-3-hydroxyvalerat) [P(3HB-ko-3HV)] in soil has been carried out. Plastic film was produced by using blending technique and followed by solved casting at various composition. The biodegradation testing was conduted by using soil burial method. Rseult showed that the increasing of component [P(3HB-ko-3HV)] in the mixture of plastic film was also increase the biodegradation rate of plastic film in the soil. At the composition 100:0, 95:5, 90:10 and 85:15 of plastic film in 5 weeks burial was found weigh remaining of plastic were of 99.67; 95.71; 95.03; 94.13% w/w respectively. It is also observed that the amount of bacteria in the soil were of 2.57 x 106 colonies/g.
Kajian Biodegradasi Filem Plastik Campuran Polistiren Dengan Poli (3-Hidroksibutirat) Dalam Tanah Octaviani, Melzi; Zaini, Erizal; Djamaan, Akmal
Jurnal Farmasi Andalas Vol 1, No 1 (2013)
Publisher : Jurnal Farmasi Andalas

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Abstract

The degradation of a plastic film containing polymer synthetic polystyrene (PS) and biopolymer poly(3-hydroxybutyrate) [P(3HB)] in soil has been carried out based on soil burial test. Result showed that the amount of P(3HB) in plastic film containing PS and P(3HB) influence the degradation rate of plastic film. Rate degradation measured use linear regression equality and parameter is indicated by the slope (k), degradation time 50% (t 50%), and degradation time 95% (t 95%). Degradation plastic film which occurred in soil with ratio PS/P(3HB) 85:15 was k = 0.90 %/week, t 50% = 55.13 weeks and t 95% = 105.29 weeks, followed by PS/P(3HB) 90:10 and PS/P(3HB) 95:15. In contrast, plastic film which made from pure PS (100:0) occurred slow with slope value (k) = 0.14 %/week, t 50% = 345.07 weeks, and t 95% = 655.63 weeks. Result of SEM test showed that damage occurred and erosion at surface of plastic film as long as observation time in various environment condition. 
Penggunaan Eudragit L 100 Dalam Formulasi Mikrokapsul Natrium Diklofenak Dengan Teknik Emulsifikasi-Penguapan Pelarut Rahmadevi, Rahmadevi; Zaini, Erizal; Halim, Auzal
Jurnal Farmasi Andalas Vol 1, No 1 (2013)
Publisher : Jurnal Farmasi Andalas

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It has been research about formulation diclofenac sodium that used Eudragit L100. To prepare, using emulsification-solvent evaporation technique, diclofenac sodium-Eudragit L100 microparticles with modified drug sustained release properties and span 80 is emulgator. Methode research is microcapsules were prepared by solvent evaporation method with ratio diclofenac sodium-Eudragit L100 (1:1,125;1:1,25;1:1,5;1:1,75) and characterized by micromeritics, Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), dissolution test using USP apparatus 1 and drug Embadment Efficiency. The result is the microparticle were whitish, irregular, aggregated, and in the size range of 100 – 160 µm size. Drug embedment efficiency was 53,7% - 66,3 %. Characterisation studies indicate that there was no chemical interaction between the drug and the polymer in the microparticles. In Dissolution profile ratio diclofenac sodium and Eudragit L100 can slowly drug release were after 450 minute released diclofenac sodium > 50%. Conclusion: Emulsification-solvent evaporation technique is a suitable method for preparing diclofenac sodium-Eudragit L100 multi-unit controlled release drug delivery system.
Co-Authors -, Salman Adhitya Jessica Agusri Boestari Akmal Djamaan Amri Bakhtiar Annisa Agustina Asiska Permata Dewi Asiska Permata Dewi Asiska Permatadewi Auzal Halim Auzal Halim Ben, Elfi Sahlan Deni Anggraini Deni Noviza Dhea Sultana Lutfiyah Dwi Setyawan Ellyza Nasrul Elvi Rahma Yulisman Elvita Sari Fauzi Saputra Fifi Harmely Friardi Ismed Gaesari, Sherly Rahmah Habibie Deswilyaz Ghiffari Hansen Nasif Helen Sonita Helen Sonita Henny Lucida Hulwa Salsabila Ima Kurniati Irna Kurniati Kiki Rizky Wirza Kurniati, Irna Lili Fitriani Mai Efdi Maria Dona Octavia Melisa Melisa Melzi Octaviani Muhammad Taher Muthia Fadhila Najmi Hilaliyati Netty Novitasari Novica Sari Rahmadevi Rahmi Nofita Resva Meinisasti, Resva Rifka Naura Rini Agustin Rose Intan Perma Sari Rustini Rustini Rustini Rustini S, Agnes Salman - Salman - Salman Salman Salman Umar Salman Umar Sundani N. Soewandhi Sundani N. Soewandhi, Sundani N. Syofyan Syofyan SYUKRAN HAMDENI Syukriati Chaira Trisfa Augia Uswatul Hasanah Verlia Nisrina Putri Vike Zulia Putri Vina Oktavia Yeni Novita Sari Yeyet C. Sumirtapura Yufri Aldi Yuska Noviyanty Zahara Gayo Zulhadjri Zulhadjri