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Pengaruh suplementasi spirulina terhadap beberapa parameter sindrom metabolik (studi di puskesmas lebdosari kota semarang) Sakti, Mayta; SS, Darmono; W, Nyoman Suci
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 2 (2015)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Latar belakang : Sindrom metabolik adalah kumpulan kelainan metabolik lipid maupun non-lipid yang merupakan faktor risiko penyakit kardiovaskuler, meliputi obesitas sentral, dislipidemia, hipertensi, dan hiperglikemia kronis. Spirulina mengandung beberapa bahan aktif terutama phycocyanin dan Î² karoten yang memiliki aktivitas antioksidan dan antiinflamasi. Suplementasi spirulina mempunyai aktivitas biologis seperti mencegah penyakit akibat perlemakan hati, menurunkan kadar glukosa darah, profil lipid, serta menurunkan tekanan darah.Tujuan : Menganalisis pengaruh suplementasi spirulina terhadap beberapa parameter sindrom metabolik meliputi tekanan darah (TD), kadar glukosa darah puasa (GDP), kadar trigliserida (TG), dan kadar kolesterol HDL.Metode : Desain penelitian ini adalah quasi experimental dengan control group design. Subjek sejumlah 39 pasien dibagi menjadi kelompok kontrol (n=19) dan kelompok perlakuan (n=20) secara acak. Intervensi berupa suplementasi spirulina sebanyak 3 gram selama 4 minggu. Kadar GDP, kadar TG, kadar kolesterol HDL, dan TD diukur sebelum dan sesudah intervensi. Hasil : Kadar GDP pada kelompok kontrol menurun secara signifikan (p=0.000), tetapi tidak ada perubahan pada TD, kadar TG, dan kadar kolesterol HDL. Kadar GDP (p=0,005), TG (p=0.040), dan TD sistolik (p=0.010) menurun secara signifikan tetapi perubahan kadar kolesterol HDL (p=0,970) dan TD diastolik (p=0,655) tidak signifikan pada kelompok perlakuan.Simpulan : Suplementasi spirulina selama 4 minggu menurunkan kadar glukosa darah, kadar TG, serta TD sistolik. Namun, tidak berpengaruh pada kadar kolesterol HDL dan TD diastolik.

Pengaruh pemberian rumput laut sargassum sp terhadap kadar hemoglobin dan feritin serum Yuniarti, Anita; Hadisaputro, Soeharyo; W, Nyoman Suci
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 1 (2016)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Anemia is a global phenomenon involving developing countries. Fifty percent of anemia cases is caused by iron deficiency. Indonesia is a tropical country that is rich in various kinds of marine plants and still not used optimally.Sargassum sp is one of high iron contains seaweed but still less utilized. Objectives: the aim of this study was to analyze the influence of Sargassum sp on hemoglobin and serum ferritin level. Methods : a simple randomized with pre and posttest control group design was used in this study. Sixteen Wistar male rats were divided into 2 groups (1) control (2) treatment and fed with Sargassum sp 0,49 g for 14 days. During the treatment pre and post hemoglobin and serum ferritin was measured. Results : : iron level in Sargassum sp was 122,37mg/g and Pb level was 0,00009%. In the treatment group hemoglobin level was significantly increased 5,24 mg/dl (p<0,05) and serum ferritin was increased 4,20 Âµg/ml (p>0,05). Conclusion : sargassum sp increased hemoglobin level on anemic wistar rat but not in serum ferritin significantly.Â

Status antioksidan dan oksidatif laki-laki yang mengalami kegemukan dengan pemberian minuman rosela ungu Sriyanti, Sriyanti; Damayanthi, Evy; Anwar, Faisal
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 2 (2019)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Rosela (Hibiscus sabdariffa L.) is an anthocyanin-rich plant that has good antioxidant capacity. However, the utilization was limited to red roselle, while previous studies showed that anthocyanin content was found to be higher in the thick roselle.therefore, this is an opportunity to develop purple roselle products as a preventive effort for degenerative diseases in men with fatness. Subjects in this study were male by considering the effect of estrogen on women which could play a role in suppressing oxidative stress.Objectives : This study aimed to analyze antioxidant (SOD/Superoxide dismutase) and oxidative status (MDA/malondialdehyde) level in obese adult men after administration of purple rosela drinks.Â Methods : This study was quasi-experimental with pre-post test. Eighteen obese subjects in the security unit were divided into two groups, namely the intervention group and control group. Intervention group (n = 9) was given purple rosela drinkin the amount of 480 mL/day, while the control group (n = 9) was given an equivalent amount of purple rosela drink without rosela. The subjects were daily administered for 6 weeks. Characteristic, anthropometric, food consumption and blood sample data were collected at the beginning and end of the intervention. Data analysis was performed by descriptively, paired t-test, independent t-test, ANCOVA.Results : The analysis showed that purple rosela drink tend to increase SOD levels (0.45 Â± 0.14; 1.35 Â± 0.71; p-value = 0.008) but this value was not significantly different from the control group (p-value = 0.128). MDA levels did not significantly different between the intervention and control groups (0.025 Â± 0.083;-0.125 Â± 0.60; p-value = 0.473).Conclusion : These results showed that administering 480 ml of purple rosela drink did not improve antioxidant and oxidative status in obese adult men.

Pengaruh asupan energi dan protein terhadap perubahan status gizi pasien anak selama dirawat di RSUP Dr. Kariadi Semarang Bandawati, Bandawati; Mexitalia, Maria; Rahfiludin, M. Zen
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 4, No 2 (2016)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Adequate energy andÂ proteinÂ intakeÂ forÂ childrenÂ patients is required as efforts to prevent decline in nutritional status during hospitalization. Nutritional support is a part of therapy which has an important role in the recovery.Objective : To analyze the effect of energy and protein intake on changes of nutritional status in children patients during hospitalized.Method : Observational study with cohort prospective design, from March to April 2014. Subjects were 52 children, 2-14 years old from pediatrics unit in Dr. Kariadi Central General Hospital Semarang. Sampling were choosen by consecutive sampling, hospitalized for >7 days and according inclusion criteria. Body weight and height data were measured at admission and discharge. Nutritional status determined using weight for height Z Score, according to WHO 2005 child Growth Standards. Food intake data collected by Comstock Methode and recall 24 hours. Data analyzed by chi-square and fisher test.Result : There were 48,1% subjects with insufficient energy and 53,9% with insufficient protein intakes. 48,1% subjectsÂ were declining in nutritional status after hospitalization. There was correlation between energy (p=0,003) and protein (p= 0,003) intakes on changes of nutritional status in children patients during hospitalized. Â Subjects with insufficient energy intakes were 26 times at risk (95% CI 3,31-291,09) of declining of BW/BH Z Score than sufficient subjects. Subjects with insufficient protein intake were 20 times at risk (95% CI 4,24-230,52) of declining of weight for height Z Score than sufficient subjects.Conclusion : Insufficient energy and protein intakes can decline nutritional status in children during hospitalized.

Faktor yang berhubungan dengan perilaku konsumsi buah dan sayur siswa SMP di Denpasar Rachman, Bella Nadya; Mustika, I Gede; Kusumawati, I. G. A Wita
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 6, No 1 (2017)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Adolescence is the transition from child to adulthood. Adolescents usually change their lifestyle, includes consumption patterns, because it is influenced by peersâ€™ environment. Adolescents nutritional needs are relatively large because of rapid growth and development process. One of the nutrition problems among adolescents is the lack of fruit and vegetable consumption that is influenced by internal and external factors.Objective : The purpose of this research was to know the relationship between attitude, nutrition knowledge, food preference, food availability, media exposure, and parents income with fruit and vegetable consumption behavior among SMPK 1 Harapan students. Methods : This study used cross sectional design and was conducted on April-May 2017. Subjects of this study were 85 grade VIII students selected by using simple random sampling. Information on attitude, nutrition knowledge, food preference, food availability, media exposure, and parentsâ€™ income were collected using questionnaire, while fruit and vegetables consumption behaviour were collected using semi quantitative food frequency questionnaire (SQ-FFQ).Results : The results of this study showed that most subjects has good fruit and vegetables consumption behavior (71.8%). There was a significant correlation betweenÂ fruit and vegetables consumption behaviour with attitude (p<0,01), nutrition knowledge (p<0.01), food availability (p<0.01), media exposure (p<0.01), and parents income (p<0.01), but not related with food preference (p = 0.55).Conclusion :This study indicated a significant relationship between attitude, nutritional knowledge, food availability, media exposure, and parents income with Â fruits and vegetables consumption behaviour.

Pola makan dan indikator lemak tubuh pada remaja Fayasari, Adhila; Julia, Madarina; Huriyati, Emy
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 1 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Previous studies has focused on intakes of individual nutrients and/or foods or food groups to specific effect on health, but there were still not clear about the effect of dieting pattern and food choice to overweight/obesity indicators like BMI-for Age, fat percentage, waist circumference and waist to height ratio and which food group has the most effect to obesity indicators.Objective: This study examined the association of meal pattern to BMI-for Age, fat percentage, waist circumference and waist to height ratio.Methods: This cross sectional study involved 738 individuals aged 15-18 years old adolescents in public school in Kota Yogyakarta. Height and waist circumference were measured by microtoise and metline. Weight and fat percentage were measured by hand-to-foot BIA. BMI-forâ€“age were determined by WHO Antroplus. Dieting pattern was determined by self-reported questionnaire food frequency questionaire which consisted of 91-food item. Data were analyzed by t-test, and linier regression and multiple regression.Results: Overweight and obese were present in 13.41% and 5.43% subjects. In linear regression analysis, legumes, one dish meal, snacks, and sweetened beverages were negatively associated to BMI for age, waist circumference, waist to height ratio and fat pecentage (p<0.05). While in food items analysis, legumes, snacks and sweetened beverages were associated with the increase of waist circumference and fat percentage, while milk and soft drink as protective factor to the increase of fat percentage (-1.70 (-2.40;-1.00); -1.68 (-2.78;-0.58)).Conclusion: In a conclusion, increase in BMI for age and waist circumference are more affected by the intake of high frequency of macronutrients, while increase in fat percentage were associated with sweetened beverages consumption.

Efek ekstrak daun sirsak (Annona muricata Linn) terhadap profil lipid tikus putih jantan (Rattus Norvegicus) Wurdianing, Indrawati; Nugraheni, SA; Rahfiludin, Zen
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Lipid profile effects is a risk factor for Coronary Heart Disease. Soursop leaves (Annona muricata L) isa traditional medicine plant containing metabolic compounds that contribute to the improvement of the lipid profile.Objective: To determine the effects of soursop leaves extract on lipid profile (total cholesterol, LDL cholesterol, HDLcholesterol and triglyceride).Methods: An experimental study using randomized pre-posttest with control group design. Sample consisted of 28 maleWistar rats, were divided into four groups. The control group (K) was only given High Fat High Cholesterol (HFHC)diet and treatment groups (P1, P2, P3) were given a HFHC diet plus Annona muricata L extract with doses of 100, 200and 300 mg/kgBB per day for 28 days respectively. Data were analyzed by Wilcoxon test, Kruskal-Wallis and MannWhitney.Results: The mean total cholesterol level significantly decreased in the treatment group P1 (p = 0.028) from 60.7 mg/dl(47.6-75.3) to 45.5 mg/dl (38.4-62.4). Mean HDL cholesterol level significantly increased in the treatment group P2(p=0.043) from 26.0 mg/dl (19.7-35.3) to 27.9 mg/dl (18.8-38.0). The mean levels of LDL cholesterol and triglyceridedecreased but not significantly.Conclusion: The administration of Annona muricata L extract can decrease total cholesterol and increase HDLcholesterol significantly.

Tepung ubi kayu (manihot esculenta) dan tepung tempe kedelai mempengaruhi pengembangan volume dan mutu gizi protein roti tawar Nanik Hamidah; Anang M Legowo; Syaiful Anwar
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 4, No 1 (2015)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Backround: Bread was a carbohydrate source’s food, was made from wheat flour. Cassava flour as substitution for wheat flour by modification process used physic method (boiling) to obtain resitant starch. Collaboration cassava flourwith tempeh flour to add protein velue. The research for attest substitution wheat flour with cassava flour and tempeh flour influence to volume characteristics and quality of protein nutrient for white breadMethods:The research methods used exsperiment with completely randomized design which consists of 5 treatment with 4 replications. Cassava flour was processed by modification used physical methods (boiling).Proportion for tempeh and cassava flour 0%, 6%, 12%, 18%, 24% combinated by tempeh flour proportion 3:1. Dependent variabel were size of volume white bread, quality of protein nutrient. Data Analysis used Anova. Result:The result of those research were found that the best chararacteristic from white bread was treatment 6%. Size of volume 3,15ml/g was size volume bread from composite flour ingredient. Quality of nutrient for protein consist of protein content increased from 6,15% to 8,76%, protein digestibility increased from 11,7% to 13,83%was compared for treatment 0%. Conclusion: Substitution wheat flour with cassava flour and tempeh flour influence white bread organoteptic (texture, colour (crumb, crust), taste), size of quality of nutrient protein.

Hubungan perilaku Keluarga Sadar Gizi (KADARZI) dan Perilaku Hidup Bersih Sehat (PHBS) pada tatanan rumah tangga dengan status gizi balita usia 24-59 bulan Hartono, Hartono; Widjanarko, Bagoes; EM, Mexitalia Setiawati
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 2 (2017)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: The prevalence of malnutrition among toddler in Kotabaru district was still high at 20,86 %. The family implemented Kadarzi was 56,24 % while the family who implemented PHBS was 42,48 %, this prevalence was still low. Objective: The purpose was analyzed the relationship between Kadarzi and PHBS behavior of households with nutritional status of toddler of 24-59 months. Â Methods: The design was cross sectional study conducted in Puskesmas Dirgahayu. Subjects were children aged 24-59 months who lived in Puskesmas Dirgahayu area, who coverese with inclusion and exclusion criteria twose, subjects are 90 respondens. Sampling technical by simple random sampling. Analysis tests used chi square test and logistic regression with 95% confidence level. Questionnaire was used as tools research, energy and protein intake was measured by recall method.Results: The results showed 27,8 % children was categorized as malnutrition status, 72,2 % family implemented Kadarzi and 70,0 % Kadarzi behave uncategorised healthy home. Analysis of the data showed no significant relationship between Kadarzi behavior with nutritional status (p=0,000, OR=31,13). There was a significant relationship between clean and healthy behavior with nutritional status (p=0,000, OR=22,56). Analysis of multiple logistic regression test obtained dominant factor associated with nutritional status is Kadarzi behavior (p=0,000, OR=0,08). Conclusion: There was a significant relationship between Kadarzi and PHBS behavior of households with nutritional status of toddler 24-59 months.

Konsumsi tinggi lauk hewani, rendah sayur dan rendah aktivitas fisik berhubungan dengan kejadian kelebihan berat badan pada anak sekolah dasar Triandhini, R.L.N.K. Retno; Kinasih, Angkit; Sriwijayanti, Anik
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 6, No 2 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Overweight and obesity in children are becoming a global health issue that needs special attention. Overweight currently occur not only in urban areas but also in rural areas. One factor that affects over nutrition is the imbalance between food intake and physical activity. Objective : The objective of this study is to analysis differences in food pattern and physical activitiy between overweight and normal children. Methods : This study was used cross sectional design. Samples were 10-12 year olds students from 13 elementary schools in Getasan Subdistrict. Dietary intake were measured by Food Frequency Questionnaire (FFQ) form and physical activity were measured by Physical Activity Questionnaire For Older Children (PAQ-C) form. Data were analyzed by Chi-Square and independent t test. Results : There are significant correlation between physical activity and the incidence of overweight in children (Ï=0,003). There are significant differences (Ï<0,05) in carbohydrates, animal protein, plant protein and vegetables intake (Ï=0,001, Ï=0,001, Ï=0,001, Ï=0,001) between normal and overweight groups.Conclusion : There are significant correlation between physical activity and the incidence of overweight in children. There are significant differences in carbohydrates , animal protein, plant protein and vegetables intake between normal and overweght groups.

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