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Health and Medical Journal
Published by Universitas Baiturrahmah
ISSN : 26852772     EISSN : 2685404X     DOI : https://doi.org/10.33854/heme
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Health & Medical Journal with registered number pISSN: 2685-2772 and eISSN: 2685-404X is a peer-review journal published by Medical Faculty of Universitas Baiturrahmah. The frequency of publishing is two issues in a year. The topics covered include the fields of Allergy and Immunology, Anesthesiology, Cancer and stem cells, Cardiovascular, Cell and Molecular Biology, Children's Health, Dermato-venereology, Geriatrics, Histopathology, Internal Medicine, Neuro-psychiatric treatment, Ophthalmology, Otorhinolaryngology, Physical medicine and rehabilitation, Physio-pharmacology, Pulmonology, Radiology, Surgery includes orthopedics and urology, Obstetrics and Gynecology, Science of nutrition, Clinical Pathology, Anatomy Pathology, Parasitology, Microbiology, Public Health and Medical Education. Submissions are welcome from other clinically relevant areas. However, the Journal emphasizes publishing high-quality and novel research.
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Articles 130 Documents
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Bullous Systemic Lupus Erythematosus Mimicking Bullous Pemphigoid: A Case Report Vesri Yossy; Gardenia Akhyar; Alimuddin Tofrizal
Health and Medical Journal Vol 3, No 2 (2021): HEME July 2021
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.091 KB) | DOI: 10.33854/heme.v3i2.667

Abstract

Introduction: Bullous systemic lupus erythematosus (BSLE) is an infrequent but distinct presentation of systemic lupus erythematosus (SLE) in less than 5% of lupus cases. It is characterized by vesicobullous skin eruption in SLE that can develop either before or after SLE diagnosis has been established. Distinguish between BSLE with other autoimmune blistering diseases such as bullous pemphigoid (BP), dermatitis herpetiformis, linear IgA, etc., is very important to prevent misdiagnosis. The physician must be able to combine clinical, histological and immunofluorescence finding for the diagnosis approach. We report a case of blistering skin eruption in SLE patient. Case Report: A 19-year-old female patient complained of tense blistering on her lip, face and wrists since one month ago. She was diagnosed with SLE two weeks ago. The dermatological state showed bullae and vesicle on erythematous/ normal base, erosions, excoriation and blackish red crust on the lip, face, armpit, neck, abdomen and wrists. Histopathological examination of the lesion showed sub-epidermal bullae containing PMN leukocytes consist of abundant neutrophils, only occasional eosinophils and the presence of keratotic plugs. Direct immunofluorescence (DIF) of the skin showed linear deposition of IgG, IgA, IgM and C1q at the dermo-epidermal junction. This patient exhibited similar features to both BSLE and BP with tensed clear blisters and subepidermal cleft. BSLE differ from BP by abundant neutrophils found on histopathological examination, whereas BP has abundant eosinophils. Conclusion: Immunofluorescence examination shows linear IgG in BP, whereas linear or granular IgG in BSLE. Establishing the correct diagnosis is important to prevent misdiagnosis and mistreatment.
Laboratory Examination in Hepatocelullar Carcinoma Debie Anggraini
Health and Medical Journal Vol 1, No 2 (2019): HEME July 2019
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (698.945 KB) | DOI: 10.33854/heme.v1i2.241

Abstract

Hepatocellular carcinoma (HCC) is a malignant tumor originating from hepatocyte cells including primary malignant tumors of the epithelial liver. Hepatocellular carcinoma is the fifth most malignant in the world and the third largest cause of death of all malignancies. Diagnosis of HCC is obtained from the patient's history, examination of the patient, by imaging (ultrasonography, MRI or CT scan) and an increase in serum tumor biomarkers of alpha feto protein (AFP) (> 400 ng mL). Early diagnosis is important to increase the patient's life expectancy and only 30-40% of patients are diagnosed at an early stage. Biomarkers in HCC not only help in diagnosing but also predict prognosis or recurrence and in choosing therapy. The stability of miRNA in blood circulation makes miRNA an ideal candidate for use in the diagnosis and treatment of cancer. Objective: to briefly review all current information about HCC. Conclusion: HCC diagnosis is obtained from the patient's history, physical examination, imaging (ultrasonic, MRI or CT scan that shows the presence of a typical liver mass for HCC) and an increase in AFP serum (> 400 ng / mL). Biomarker examination and evaluation is still very limited, one of which is the examination of MicroRNAs
Peningkatan Kadar Lipoprotein-Associated Phospholipase A2 Meningkatkan Kejadian Stroke Iskemik Akut Syarif Indra
Health and Medical Journal Vol 3, No 1 (2021): HEME January 2021
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (328.327 KB) | DOI: 10.33854/heme.v3i1.485

Abstract

Introduction: Stroke is a major health problem in the world, and associated with mortality, disability, and economic burden. Stroke is the second leading cause of death in the world after heart disease and cause of disability in adults. Several recent studies show that levels of Lp-PLA2 contribute to high serum lead to ischemic stroke, whereas some others do not get the association. Aims: studies an association between serum Lp-PLA2 with incident ischemic stroke. Method: This study is a descriptive analytic comparative with cross sectional design in the Neurology ward RS. DR. M. Djamil Padang between October 2013 to April 2014 with total of 88 subjects consisting of 44 subjects ischemic stroke patients and 44 healthy control group who participated in the study. Statistical analysis is used parametric test with unpaired t test, test for normality with the Kolmogorov-Smirnov test, and logistic regression analysis. Result: P value 0.05 was considered statistically significant. The mean age of subjects in the group of ischemic stroke patients was 57.30 ±8.86 years old. Female in patients with ischemic stroke group was 23 people (52,3%). Mean levels of Lp-PLA2 serum in patiens with ischemic stroke group was 103.49±48.00 ng/mL. A significan association between serum levels of Lp-PLA2 with incident ischemic stroke with p<0.05. Conclusion: There was a significant relation in elevation of serum Lp-PLA2 levels with incident of ischemic stroke.
Hubungan Gangguan Fungsi Kognitif Dengan Kejadian Depresi Pada Lansia Di Posyandu Lansia Ikur Koto Wilayah Kerja Puskesmas Ikur Koto Kota Padang Indri Zaliavani; Mutiara Anissa; Fidiariani Sjaaf
Health and Medical Journal Vol 1, No 1 (2019): HEME January 2019
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (466.927 KB) | DOI: 10.33854/heme.v1i1.224

Abstract

Latar Belakang: Pada usia lanjut stres lingkungan dan penurunan fungsi kognitif sering menyebabkan depresi. Depresi yang tidak tertangani dengan baik dapat menyebabkan peningkatan penggunaan fasilitas kesehatan, pengaruh negatif terhadap kualitas hidup lansia, bahkan dapat menyebabkan kematian. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan gangguan fungsi kognitif dengan kejadian depresi pada lansia di posyandu lansia Ikur Koto wilayah kerja Puskesmas Ikur Koto, Kota Padang. Metode: Jenis penelitian ini adalah penelitian analitik korelatif dengan pendekatan cross-sectional. Penelitian telah dilakukan di posyandu lansia Ikur Koto pada bulan Februari 2019.  Sampel dalam penelitian ini lansia yang terdata posyandu lansia Ikur Koto wilayah kerja Puskesmas Ikur Koto, Kota Padang yang berjumlah 51 lansia. Analisa data adalah univariat disajikan dalam bentuk tabel distribusi frekuensi dan analisa bivariat dengan menggunakan uji spearman dengan menggunakan program SPSS. Hasil yang diperoleh dari 51 responden, usia terbanyak 60-74 tahun (elderly) yaitu (70,6%), jenis kelamin terbanyak (94,1%) adalah perempuan, pendidikan terbanyak (56,9%) adalah SD, status perkawinan terbanyak (52,9%) adalah kawin, status kesehatan terbanyak (58,8%) tidak menderita penyakit kronis dan riwayat medikasi terbanyak (98%) tidak mengkonsumsi obat, sebagian besar (71%) tidak mengalami depresi,  paling banyak (41,9%) mengalami gangguan fungsi kognitif ringan dan terdapat hubungan yang signifikan antara gangguan fungsi kognitif dengan kejadian depresi pada lansia dengan nilai p=0,007<0,05 dan r=-0,373. Kesimpulan dari penelitian ini adalah terdapat hubungan yang signifikan antara gangguan fungsi kognitif dengan kejadian depresi pada lansia di posyandu lansia ikur koto wilayah kerja Puskesmas Ikur Koto, Kota Padang.
Karakteristik Penderita Epilepsi di Bangsal Anak RSUP Dr. M. Djamil Padang Tahun 2018 Khalvia Khairin; Laura Zeffira; Rifkind Malik
Health and Medical Journal Vol 2, No 2 (2020): HEME July 2020
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.963 KB) | DOI: 10.33854/heme.v2i2.453

Abstract

Latar Belakang: Epilepsi merupakan suatu keadaan yang ditandai adanya bangkitan yang terjadi secara berulang akibat terganggunya fungsi otak yang disebabkan oleh muatan listrik yang abnormal pada neuron-neuron otak. Epilepsi memiliki dua kategori kejang yaitu kejang fokal dan kejang umum. Insiden epilepsi diperkirakan lebih banyak terdapat pada negara berkembang daripada negara maju. Pada tahun 2017, jumlah kasus epilepsi anak di Sumatera Barat terutama di RSUP Dr. M. Djamil Padang ada 1081 kasus pada rawat jalan dan satu kasus rawat inap dan diperkirakan akan terus meningkat setiap tahunnya. Tujuan: Untuk mengetahui karakteristik penderita epilepsi di bangsal anak RSUP Dr. M. Djamil Padang tahun 2018. Metode: Penelitian ini dilakukan di RSUP Dr. M. Djamil Padang. Penelitian ini bersifat deskriptif dengan rancangan cross sectional. Sumber data dari data sekunder yang berasal dari rekam medis. Sampel dipilih dengan menggunakan kriteria inklusi dan eksklusi. Analisis data menggunakan analisis univariat. Hasil: Didapatkan dari 65 sampel yang menderita epilepsi yaitu usia 0-5 tahun sebanyak 37 orang (56,9%), jenis kelamin laki-laki sebanyak 39 orang (60%), tidak memiliki riwayat epilepsi keluarga sebanyak 62 orang (95,4%), gambaran EEG gelombang sharp wave dan spike sebanyak 30 orang (46,2%), tipe kejang generalized sebanyak 57 orang (87,7%) dan asam valproat sebagai salah satu penatalaksanaan epilepsi sebanyak 32 orang (49,2%). Kesimpulan: Dari hasil penelitian ini, dapat disimpulkan bahwa penderita epilepsi terbanyak adalah usia 0-5 tahun dengan jenis kelamin laki-laki serta tidak memiliki riwayat epilepsi dalam keluarga. Tipe gambaran EEG yaitu gelombang sharp wave dan spike, tipe kejang umum dengan penatalaksanaan terbanyak asam valproat.
Hubungan Kadar Laktat Dehidrogenase Dengan Derajat Preeklampsia-Eklampsia Di Rsup Dr.M.Djamil Padang Tahun 2017 Tia Kartika; Prima Adelin; Rinita Amelia
Health and Medical Journal Vol 1, No 1 (2019): HEME January 2019
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (429.104 KB) | DOI: 10.33854/heme.v1i1.212

Abstract

Pendahuluan: Preeklampsia merupakan penyebab kematian ibu yang tinggi setelah perdarahan. Laktat dehidrogenase (LDH) berguna sebagai penanda biokimia untuk menggambarkan beratnya preeklampsia-eklampsia.Tujuan penelitian ini adalah mengetahui hubungan kadar laktat dehidrogenase dengan derajat preeklampsia-eklampsia di RSUP DR. M.Djamil Padang tahun 2017. Metode: Jenis penelitian ini adalah penelitian observational analitik  menggunakan data sekunder yang berasal dari rekam medis. Tempat penelitian dilakukan di Instalasi Rekam Medis Rumah Sakit Umum Pusat DR. M. Djamil Padang. Waktu penelitian dilakukan pada bulan Desember 2018 – Januari 2019 . Sampel adalah pasien preeklampsia-eklampsia yang dirawat di instalasi rawat inap dan instalasi rawat jalan RSUP DR.M.Djamil Padang yang memenuhi kriteria inklusi dan eksklusi yang diambil dengan menggunakan teknik simple random sampling berjumlah 32 orang. Hasil: Analisa univariat disajikan dalam bentuk tabel dan analisa bivariat disajikan dalam bentuk tabel menggunakan uji Spearman. Berdasarkan hasil penelitian diperoleh pasien preeklampsia berat 21 orang (65,6%) memiliki rerata kadar laktat dehidrogenase 679.05 u/l dengan rentang 313-1755 dan pasien eklampsia 11 orang (34,4%) memiliki rerata kadar laktat dehidrogenase 1838.64 u/l dengan rentang 420-5508. Uji Korelasi Spearman diperoleh nilai signifikan 0.001 dan korelasi 0.545. Kesimpulan: Terdapat hubungan antara kadar laktat dehidrogenase dengan derajat preeklampsia-eklampsia (p<0,05) dengan korelasi sedang (r=0.545)
PERBEDAAN INSIDENSI DIABETES MELITUS TIPE 2 DAN HBA1C PADA POPULASI TERPAPAR-TIDAK TERPAPAR EMISI PABRIK SEMEN PADANG Prima Adelin; Rismawati Yaswir; Zelly Dia Rofinda; Rizanda Machmud; Husna Yetti
Health and Medical Journal Vol 3, No 2 (2021): HEME July 2021
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (943.083 KB) | DOI: 10.33854/heme.v3i2.632

Abstract

Background: Cement factory emission disrupt blood glucose control through insulin resistance mechanism, thus increasing incidence of type 2 diabetes mellitus (DM type 2). Aim: Aim of this study is to determine incidence’s differences of DM type 2 and mean HbA1c patients with DM type 2 within population exposed and unexposed cement Padang factory emission. Method: This was a cross sectional analytic study with cluster sampling that conducted on June-December 2015 with 129 and 125 participant from exposed and unexposed areas. Age of participants are 20-79 years old. Incidence is total new cases per total sample in exposed or unexposed area. HbA1c were measured with immunoturbidimetry method. Data were analyzed by chi-squared test to asses differences of two proportions and t test to asses differences of two averages. Results: The incidence DM type 2 are 3,9% and 7,2% respectively in exposed and unexposed areas, without significant difference (p>0,05). The mean HbA1c patients DM type 2 are 10,0(2,4)% and 8,8(1,6)% in exposed and unexposed areas, without significant difference (p>0,05). Conclusions: There were no significant differences incidence of DM type 2 and  mean HbA1c patients DM type 2 in the populations exposed and unexposed cement Padang factory emission. Cohort studies is required to see the effects of cement factory emission
Visual Outcome after Oral versus Intravenous Methylpredisolone Therapy for Bilateral Optic Neuritis in Adults Naima Lassie; Hartono Hartono
Health and Medical Journal Vol 2, No 1 (2020): HEME January 2020
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (744.61 KB) | DOI: 10.33854/heme.v2i1.260

Abstract

Introduction: Bilateral optic neuritis in adults is rarer then unilateral optic neuritis. The purpose of this study was to know the clinical profile and to know the visual outcome of bilateral optic neuritis in adult patients after oral versus intravenous methylprednisolone therapy. Methods: A retrospective review of patients with bilateral optic neuritis referred to dr.Sardjito General Hospital, Yogyakarta from 2011-2014. The data consisted of bilateral optic neuritis, unassociated with other pathologic processes. There are two groups of patients: Group A taking oral methylprednisolone 1mg/kgBB and Group B received intravenous methylprednisolone (as ONTT guideline). Visual acuity, visual field with Goldmann Perimetry, RAPD (Relative Afferent Puppilary Defect), Ishihara test and direct ophthalmoscopy evaluation were recorded and analysed in both group at baseline, 1 week, 1 month and 3 months follow up.  Results: Nineteen women and 9 men, with age range of 18-54 years old, had bilateral optic neuritis. The majority of the patients suffered from retrobulbar neuritis (43%), papilitis (39%) and neuroretinitis (18%). The average visual acuity before treatment in Group A was 0.22 ± 0.29 and in Group B had poorer average visual acuity 0.03±0.04 (p>0.05). But the trend of visual recovery in Group B with visual acuity at baseline worsen, the recovery of visual acuity was faster and better at one week. After one month the visual acuity was comparable in both groups (p>0.05). Conclusions: Visual improvement in early period of adult bilateral optic neuritis was similar after oral and intravenous methylprednisolone therapy. 
Hubungan Kualitas Tidur Terhadap Konsentrasi Belajar Mahasiswa Fakultas Kedokteran Universitas Baiturahmah Padang Angkatan 2018 Syarifah Fazhilah Djamalilleil; Rosmaini Rosmaini; Nadia Purnama Dewi
Health and Medical Journal Vol 3, No 1 (2021): HEME January 2021
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (291.622 KB) | DOI: 10.33854/heme.v3i1.339

Abstract

Introduction: The lack of concern toward sleep quality is frequently found on students of high schoold, hectic workers and college students, the impacts of sleep lack could affect to learning concentration. Aims: To find out the correlation between sleep quality and learning concentration ,students of medical faculty, University of Baiturrahmah Padang in Second Year.Method: The scope of this study covers the field of general medical science, this study was conducted at the Faculty of Medical, University of Baiturahmah Padang on April 2019 to January 2020. The type of this study was descriptive analytic study with cross sectional study design. Affordable population in the study were students of the Faculty of Medical, University of Baiturahmah in second year, the amount was 150 people with 76 samples by using random sampling technique. Univariate data analysis was presented in the form of frequency and percentage distributions as well as bivariate analysis using chi-square test and data processing using computerized SPSS program version 24.0. Result: Based on the results of the study, People who had the poor sleep quality are 53 people (69.7%), had a poor learning concentration are 42 people (55.3%) and there was a correlation between sleep quality and learning concentration of students at the Faculty of Medical, University of Baiturrahmah, Padang in second year P = 0.034 <0.05.Conclusion: It is proven that there was a correlation between sleep quality and the learning concentration of students at the Faculty of Medical, University of Baiturrahmah Padang, Second year.
Karakteristik Laser Retinopexy pada Pasiendengan Tear Retina di Divisi Vitreoretina RS Cipto Mangunkusomo Periode Januari – Desember 2018 Haves Ashan
Health and Medical Journal Vol 1, No 2 (2019): HEME July 2019
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (71.775 KB) | DOI: 10.33854/heme.v1i2.237

Abstract

Latar belakang: Retinal detachment merupakan suatu kondisi serius yang mengancam penglihatan sehingga dapat menimbulkan komplikasi kebutaan. Satu – satunya tatalaksana untuk retinal detachment  tersebut adalah tindakan bedah, dimana tidak seluruh tindakan bedah pada kasus retinal detachment memiliki tingkat keberhasilan yang baik. Oleh karena itu, sangat penting untuk dapat menemukan tear pada retina, sebelum berkembang lebih lanjut menjadi detachment. Tujuan: mengetahui karakteristik Laser Retinopexy pada Pasiendengan Tear Retina di Divisi Vitreoretina RS Cipto Mangunkusomo Periode Januari – Desember 2018. Metode: Penelitian bersifat deskriptif retrospektif menggunakan data rekam medis. Tempat penelitian yaitu di Divisi Vitreoretina, Departemen Ilmu Kesehatan Mata FKUI-RSCM Kirana, Jakarta. Waktu dan sampel penelitian diambil dari rekam medis periode Januari sampai Desember 2018. Hasil: Karakteristik umum subjek penelitian, dari 14 subjek, sebanyak 9 orang (64,3%) berjenis kelamin pria dan 5 orang (35,7%) berjenis kelamin wanita. Mayoritas pasien memiliki rentang usia 41-50 tahun (42,8%) dan 31-40 tahun (28,6%), rentang usia 51-60 tahun (28,6%). Asal rujukan yaitu dari Jabodetabek sebesar 92,9% dan luar Jabodetabek sebesar 7,1%. Ditemukan lateralitas terbanyak didapatkan pada mata kiri yaitu 10 orang (71,4%) sedangkan mata kanan 4 orang (28,6 %). Visus awal saat datang mayoritas antara ≥ 6/18 yaitu sebanyak 11 orang (78,6 %), visus < 6/18 – 6/60  sebanyak 2 orang (14,3%), visus < 1/60 – LP sebanyak 1 orang (7,1%). Dua minggu pasca laser retinopexy didapatkan visus ≥ 6/18 yaitu sebanyak 11 orang (78,6 %), visus < 6/18 – 6/60  sebanyak 2 orang (14,3%), visus < 1/60 – LP sebanyak 1 orang (7,1%). Satu pasien mengalami penurunan visus dari 0,5/60 menjadi 1/300. Lokasi tear retina mayoritas ditemukan di Superotemporal sebanyak 7 orang (50,0 %), kemudian Inferotemporal sebanyak 6 orang (42,9 %), dan Superonasal sebanyak 1 orang (7,1 %). Satu pasien mengalami komplikasi setelah 2 minggu tindakan laser retinopexy, dimana tear retina berkembang menjadi Rhegmatogen Retinal Detachment. Kesimpulan: Lokasi tear retina mayoritas ditemukan di Superotemporal sebanyak 7 orang (50,0 %), kemudian Inferotemporal sebanyak 6 orang (42,9 %), dan Superonasal sebanyak 1 orang (7,1 %). 

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