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All Journal Indonesian Journal of Cancer Chemoprevention Journal of Mathematical and Fundamental Sciences JPM17: Jurnal Pengabdian Masyarakat UNEJ e-Proceeding Berkala Kedokteran JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Panrita Abdi - Jurnal Pengabdian pada Masyarakat Universa Medicina ALCHEMY Jurnal Penelitian Kimia JSFK (Jurnal Sains Farmasi & Klinis) PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Abdi: Media Pengabdian Kepada Masyarakat Journal of halal product and research (JHPR) Berkala Ilmiah Kimia Farmasi Pharmaceutical Sciences and Research (PSR) Camellia
Juni Ekowati
Departemen Ilmu Kefarmasian, Fakultas Farmasi, Universitas Airlangga
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Effect of para (p) position methoxy group on thesynthesis of Benzohydrazide derivatives from Methylbenzoate starting material Suzana Suzana; Erlina Ardhayanti; Kholis Amalia Novianti; Juni Ekowati; Tutuk Budiati
Berkala Ilmiah Kimia Farmasi Vol. 9 No. 2 (2022): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikfar.v9i2.42705

Abstract

The synthesis of N'-benzylidenebenzohydrazide and N'-(4-methoxybenzylidene)benzo hydrazide had performed through condensation reaction. The reaction was performed in two stageswith methylbenzoate as the initial material. The firstphase was obtained benzohydrazide by reacting methylbenzoate and hydrazine hydrate, the second phase was obtainedthe compound of N'-benzylidenebenzohydrazide and N '-(4-methoxyibenzylidene)benzohydrazide by reacting benzohydrazide and benzaldehyde/4-methoxybenzaldehyde. The results were obtained respectively 87% and 92%. Puritytest was done by thin layer chromatography (TLC) and melting point. The melting point of benzohydrazide was 108-111oC. N'-benzylidene benzohydrazide m.p. 104-108oC and N'-(4-methoxybenzylidene)benzohydrazide m.p. 159-161oC.Identifications synthesized were confirmed by UV-VIS, FT-IR and 1H-NMR spectroscopy.
Pelatihan Pembuatan Sabun Rosella di Gresik dalam Upaya Pencegahan Penularan COVID-19 Sebagai Implementasi SDGS-3: The Training in Preparation of Rosella Hand Soap in Gresik to Prevent Transmission of COVID-19 as Implementation of SDGS 3 Juni Ekowati; Melanny Ika Sulistyowati; Achmad Toto Purnomo; Kholis Amalia Nofianti; Norhayati Norhayati; Gusti Rizaldi; Ghinalya Chalbi Ananda
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 8 No. 3 (2023): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v8i3.4588

Abstract

Efforts to inhibit the transmission of COVID-19 are continuing to this day. One of them is using hand-washing soap to prevent the transmission of this virus. The Faculty of Pharmacy, Airlangga University, seeks to implement SDGs-3 through community service activities to increase community empowerment, especially for the younger generation. The utilization of natural ingredients containing many active compounds has yet to be discovered. The solution is to provide information on the source of the active ingredients for hand washing soap, for example, the Rosella flower, explaining the mechanism of soap in inhibiting the spread of viruses and how to make hand washing soap. The activity was carried out in Gresik with counseling and training methods. The outcome was an increase in participants' understanding, as indicated by an average post-test score of >65, with an increase in score of >10% compared to the pretest. In addition, one product of Rosela flower hand washing soap was also obtained. From this activity, it was concluded that there was an increase in understanding of 28%. It is hoped that this increase in understanding and skills for the younger generation can mobilize the surrounding community so that prevention of the transmission of COVID-19 is more massive and conditions of good health and well-being in society will be achieved.
Peningkatan Pemahaman Pengelolaan Obat Keluarga dan Pangan Sehat untuk Anak sebagai Implementasi SDGS 3 di Bojonegoro: Increased Understanding of Family Medicine Management and Healthy Food for Children as Implementation of SDGS 3 in Bojonegoro Suzana Suzana; Juni Ekowati; I Nyoman Wijaya; Rosita Handayani; Siti Rahmah; Bambang Tri Purwanto; Dewi Melani Hariyadi
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 8 No. 4 (2023): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v8i4.4719

Abstract

This service activity is motivated by efforts to maintain health after the Covid-19 pandemic. The community carries out preventive efforts by providing stocks of their medicines at home. The culture of storing medicines in the household requires proper drug management to prevent drug damage due to improper storage, drug use errors, and environmental pollution due to errors in handling damaged or expired drugs. The pharmacist's role is vital in providing drug management education to the community. Another preventive effort undertaken by the community is to maintain a healthy body by applying a diet where fast food currently contains a lot of Food Additives (BTP), which can threaten long-term public health. For this reason, people need to get an education directly, so they are wise in using BTP. The solution is to educate the public regarding managing household medicines and healthy food for parents and guardians of RA Al Manshur Play Group (KB) students in Bojonegoro. Activities are packaged in counseling methods and training/practice activities. The expected outcome of the activity is an increase in the understanding of guardian parents, as indicated by an average post-test score of >65 with an increase in score of >10% compared to the pretest. By increasing the understanding of parents and teachers about managing medicines and healthy food in the family, it is hoped that conditions of good health and well-being in society will be achieved.
In silico Study on Physicochemical, Pharmacokinetic and Toxicity Profiles of Available Antiviral Drugs and The Drug-Target Interaction with Protease of SARS-CoV-2 Nuzul Wahyuning Diyah; Aileen Syifa Ghifari; Shabrina Wahyu Hidayati; Juni Ekowati
Camellia : Clinical, Pharmaceutical, Analytical and Pharmacy Community Journal Vol 1 No 2 (2022): Camellia (Clinical, Analytical, Pharmaceutical, and Pharmacy Community Journal)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: In emergency conditions such as the COVID-19 pandemic, many drugs treating SARS-CoV-2 are currently being developed through the concept of repurposing the existing drugs. This study aims to evaluate the physicochemical, pharmacokinetic and toxicity (ADMET) profiles of 15 drugs that have been used clinically for other viral diseases, and inspect their activity as antivirals against SARS-CoV-2. Methods: The physicochemical properties were obtained by using the ChemDraw and the ADMET were predicted using pkCSM on line tools. The selected drugs based on Lipinski's Rules were docked into main protease of SARS-CoV-2 (PDB. 6LU7) using Molegro program. Results: Six drugs complied with Lipinski's Rules and showed good ADMET profile except for their hepatotoxicity, but favipiravir and oseltamivir were predicted to be non-hepatotoxic. Oseltamivir also showed high binding affinity with free energy score below -100 kcal/mol. Conclusions: Oseltamivir is a potential antivirus for COVID-19 based on physicochemical, ADMET profile, and in silico activity against protease of SARS-CoV-2. 
Peningkatan Kualitas Produksi dan Keamanan Pemasaran Minuman Kesehatan Berbasis Bunga Telang pada Ibu PKK Kecamatan Rungkut Surabaya dalam mendukung SDGs-3 Good Health and Well Being: Improving the Quality of Production and Marketing of Telang Flower Based Health Drinks to PKK Women, Rungkut District, Surabaya in support of SDGs-3 Good Health and Well Being Juni Ekowati; Neny Prawitasari; Farida Ifadotunnikmah; Bastiana Bastiana; Mochammad Yuwono; Suzana Suzana; Julian Dwi Susanto; Angkasa Megistra Ulvan; Thalia Vanessa Hartono; Fawaz Shihab; Ryan Afandi; Albertus Aditya Setiawan; Winanda Rizki Febrianti
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 2 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i2.5984

Abstract

To support SDGs-3 to achieve conditions of good health and well-being amidst the conditions of society, support is needed for resilient community groups who are economically creative. The residents of Penjaringan Sari Village are among the village residents who have won Surabaya SMART City 2020. They are an alternative tourist village developing a productive economy by selling processed drinks based on Telang flowers. However, in this community group, many problems still require assistance. Efforts need to be made to solve the problems of PKK women's partners in the Penjaringansari sub-district to improve production quality, starting from preparing raw materials, selecting and using packaging correctly, and increasing the diversification of partners' processed products and product branding. This activity aims to provide community service from a team of lecturers from the Faculty of Pharmacy, Airlangga University, in collaboration with lecturers from the Faculty of Medicine, Nahdatul Ulama University, Surabaya. This activity is a tri dharma of higher education where the community can feel lecture materials, research results, and previous community service products as partners in supporting SDGs-3 Good Health and Well-being. The outcome is an increase in participants' understanding, indicated by an average post-test score of 75, with an increase of 26% compared to the pretest. Apart from that, there is an increase in skills in making syrup and Telang flower powder drinks.
Pemanfaatan Iradiasi Gelombang Mikro pada Sintesis Metil orto-metoksisinamat Istna Nur’ainul Yaqin; Juni Ekowati; Kholis Amalia Nofianti; Suzana Suzana
JSFK (Jurnal Sains Farmasi & Klinis) Vol 8 No 2 (2021): J Sains Farm Klin 8(2), Agustus 2021
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.8.2.157-163.2021

Abstract

Tujuan penelitian ini adalah mensintesis senyawa metil orto-metoksisinamat (MOMS) yang terbukti berdasarkan uji in silico dapat digunakan mengobati penyakit kardiovaskular, yaitu sebagai antiplatelet. Sintesis MOMS dilakukan dari material awal asam orto-hidroksisinamat (AOHS) dengan metode iradiasi gelombang mikro dan membandingkan profil KLT selama proses reaksi sintesis pada tiga daya iradiasi gelombang mikro tersebut (120, 280 dan 400Watt). Reaksi yang digunakan adalah reaksi metilasi pada gugus OH asam karboksilat dan gugus fenolik dari senyawa AOHS dengan dimetil sulfat sebagai agen pemetilasi. Kondisi reaksinya diatur dalam suasana basa K2CO3 menggunakan pelarut aseton. Pengambilan sampel pada proses reaksi sintesis dilakukan setiap 30 detik pada masing-masing daya microwave dan dievaluasi noda yang terbentuk pada plat kromatografi lapisan tipis (KLT), dan dilanjutkan sampai reaksi sempurna. Hasil penelitian menunjukkan bahwa kesempurnaan reaksi semakin cepat dengan bertambahnya daya microwave. Prosentase hasil yang diperoleh 72%. Berdasarkan analisis senyawa menggunakan spektrofotometer FT-IR, spektrometer 1H-NMR dan 13C-NMR, disimpulkan bahwa reaksi sintesis senyawa MOMS dapat dilakukan dengan memanfaatkan iradiasi gelombang mikro, hal ini disebabkan adanya gugus polar pada AOHS yang dapat menyerap iradiasi gelombang mikro. Semakin tinggi daya yang digunakan pada reaksi metilasi AOHS, maka semakin cepat waktu yang dibutuhkan untuk kesempurnaan reaksi
Co-Authors Achmad Toto Poernomo Achmad Toto Purnomo Adam Hermawan Adinda Adelia Wulandari Aileen Syifa Ghifari Akhmad Aminur Rizqia Albertus Aditya Setiawan Angkasa Megistra Ulvan Asri Darmawati Bambang Tri Purwanto Bastiana Bermawi Dewi Isadiartuti Dewi Melani Hariyadi Diyah, Nuzul Wahyuning Edy Meiyanto Edy Meiyanto Engrid Juni Astuti Erika Christy Marentek Erlina Ardhayanti Farida Ifadotunnikmah Fawaz Shihab Galih Satrio Putra Galih Satrio Putra, Galih Satrio Ghinalya Chalbi Ananda Ghinalya Chalbi Ananda Gusti Rizaldi Hadi Poerwono Hanifah Ridha Rabbani Heinrich Dengi I NYOMAN WIJAYA Ilham Bagus Sagitaras Imamatin Nufus Melania Isnaeni isnaeni, isnaeni isnaeni Istna Nur’ainul Yaqin Istna Nur’ainul Yaqin Itsna Nur ‘Ainul Yaqin Iwan Sahrial Hamid Iwan Sahrial Hamid Julian Dwi Susanto Kholidah Febriani M. Faris Adrianto Marcellino Rudyanto Marcellino Rudyanto Melanny Ika Sulistyowati Melanny Ika Sulistyowaty Mochammad Yuwono Mohammad Rizki Fadhil Pratama Muhamad Ilham Royyan Nafi’ Muhammad Ilham Royyan Nafi Muhammad Yuwono Muhammad Yuwono Muhammad yuwono Muhammad yuwono, Muhammad Yuwono Muhammad Yuwono Neny Prawitasari Nofianti, Kholis Amalia Noor Erma Nasution Noor Erma Nasution Noor Erma Nasution Noor Erma Nasution Sugijanto Noor Erma Nasution Sugijanto Norhayati Norhayati Paramita, Diajeng Putri Praditapuspa, Ersanda Nurma Putri Hamidah Khairunnisa Rahman, Alief Putriana Rahmana Emran Kartasasmita Rais Razak Randiman, Sugijanto Sugijanto Rian Putra Pratama Riesta Prima Harinastitic Rosita Handayani Rossa Auli Tasha Ruri Intan Nurcahyaningtyas Ryan Afandi SETIAWAN, Catur Dian Shabrina Wahyu Hidayati Shigeru Sasaki Shigeru Sasaki Siswandono, Siswandono Siti Rahmah Sovia Aprina Basukia Sugijanto Sugijanto Kartosentono Sugijanto Kartosentono Sugijanto Sugijanto Sugijanto Sugijanto Randiman Sugijanto, Noor Erma Nasution Noor Erma Nasution Sukardiman Suko Hardjono Sulistyowati, Melanny Ika Suzana Syahrani, Achmad Thalia Vanessa Hartono Tiara Puspa Asriningrum Tri Widiandani Tutuk Budiati Tutuk Budiati Tutuk Budiati Tutuk Budiati Winanda Rizki Febrianti Wiwied Ekasari