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All Journal Majalah Kedokteran Bandung Dentika Dental Journal Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Padjadjaran Journal of Dental Researchers and Students Jurnal Material Kedokteran Gigi Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI) Jurnal Health Sains

Inne Suherna Sasmita

Universitas Padjadjaran

Author-ID : 2541115

Biochemistry, Genetics & Molecular Biology Dentistry Energy Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Veterinary

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Overview of the frontal sinus anteroposterior size based on against lateral cephalometric radiographs chronological age as forensic identification Marsya, Georgiana; Sasmita, Inne Suherna; Oscandar, Fahmi
Padjadjaran Journal of Dentistry Vol 29, No 2 (2017): July
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Introduction: One part of the most important individual identification procedure is approximate age can be done on an individual living or dead. Judging from some of the methods that have been there, have not found a method forecasts age through the frontal sinuses, particularly research conducted in Indonesia. The frontal sinus can be used for identification because the frontal sinuses began to evolve and look at radiographs at the age of 7 years and did not change after the age of 20 years, it reveals the existence of differences in the size of the frontal sinuses with age. Objective: To asses of the frontal sinus anteroposterior size based on against lateral cephalometric radiographs chronological age as forensic identification. Methods: A number of samples are 502 lateral cephalometric patient data from secondary data of patients aged 7-20 years, 335 pieces of lateral cephalometric. Purpose of of the study was to asses the frontal sinus anteroposterior size chronological age as forensic identification. Radiograph female patients and 167 pieces in male patients. Data anteroposterior size of the frontal sinus is obtained by pulling the longest line perpendicular to the line of Sh-Sl. Results: The results showed that at the age of 7 years the average size of the frontal sinus anteroposterior 4.20 mm and 5.05 mm which is the smallest size, while the average size of the biggest, by 8.46 mm in women and men at the age of 11.37 mm 20 years. Conclusions: In women, the fastest increase occurred at the age of 7-8 years, males at the age of 16-18 years. The frontal sinuses anteroposterior size increases with age, both men and women.

Electro-gene therapy followed by intratumoral injection of pcDNA3.1-p27Kip1 wild type in human tongue base cancer cells SP-C3 xenograft Supriatno, S.; Sasmita, Inne Suherna
Padjadjaran Journal of Dentistry Vol 21, No 3 (2009): November
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Human tongue base cancers are characterized by a high degree of local invasion and metastasis to the regional lymph nodes and included a disease with difficult treatment. A novel method for high-efficiency and region-controlled in vivo gene transfer was developed by combining electro-gene therapy and plasmid (pcDNA). The aims of the study were to examine the efficiency of transfection of p27Kip1 gene by electro-gene therapy and to evaluate p27Kip1 gene therapy in Supriâs clone-3 (SP-C3) xenografts using pcDNA3.1-p27Kip1 wild-type (wt) and pcDNA3.1 empty vector (neo) with electro-gene therapy. To investigate gene transfer method, the enhanced green fluorescence protein (EGFP) gene was transfected into xenografts by electro-gene therapy. The efficiency of p27Kip1 gene transfection at protein level was confirmed by Western blotting. To estimate the reduction in tumour size in Wistar Balb/c mice after electro-gene therapy with p27Kip1 wt gene was examined by tumorigenesis assay. To evaluate the induction of apoptosis was carried out by colourimetric assay. The result, the growth of tumours was markedly suppressed by p27Kip1 wt gene transfection. Up-regulation of p27Kip1 protein was detected in pcDNA3.1-p27Kip1 wt. Apoptosis induction through the activity of caspase -3 and -9 was significantly increased in p27Kip1 wt-transfected tumours. These results suggest that it is possible to transfer p27Kip1 wt into tongue base cancer cell xenografts using electro-gene therapy. p27Kip1 wt had a high-potential to suppress the growth of tumours. Conclusion, electro-gene therapy followed by intratumoral injection of pcDNA3.1-p27Kip1 wt had a high-potential to suppress the growth of a human tongue base cancer cell xenograft.

The differences of caries prevalence and caries index of children in primary school with UKGS and without UKGS in Kota Batam Zulkarnain, Ratna Ayu Alia; Riyanti, Eriska; Sasmita, Inne Suherna
Padjadjaran Journal of Dentistry Vol 21, No 1 (2009): March
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

The purposes of this research were to describe the caries prevalence and caries index of children in primary school with UKGS (SD Kartini I) and without UKGS (SD 009 Bulang) in Kota Batam. Total samples of this research were 193 persons, it is consist of 107 persons from SD Kartini I and 86 persons from SD 009 Bulang. The Chi-Square Test and U Mann-Whitney Test were conducted in this research. The statistical analysis was significant for caries prevalence between children in primary school with UKGS and without UKGS with Ï2table = 2.71 and Ï2calculate = 3.73, whereas def-t index between children in primary school with UKGS and without UKGS was significant with - Ztable = - 1.96 and Zcalculate = - 2.91 with Î± = 0.05. The DMF-T index between children in primary school with UKGS and without UKGS was significant with Ztable = 1.96 and Zcalculate = 6.32 with Î± = 0,05. The conclusions of this study indicate that there were differences of caries prevalence and caries index between children in primary school with UKGS and without UKGS.

Ethanol extract of mangosteen (Garcinia Mangostana Linn) peel effect in inhibiting the growth of human tongue cancer cells Supriâs Clone 1, invitro Suanto, Edi; Oewen, Roosje Rosita; Sasmita, Inne Suherna; Supriatno, S.; Supratman, Unang
Padjadjaran Journal of Dentistry Vol 23, No 2 (2011): July
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

The incidence of tongue cancer in Indonesia reached 1.01% of all cancers and 42% of oral cavity cancer. Tongue cancer therapies including chemotherapy, radiotherapy, surgery, and all three combined therapy. Search for anti-cancer drugs currently switched on herbal plants, one of which is the mangosteen. Has the properties of mangosteen peel extract inhibited the growth of cancer cells. The purpose of the study, obtain IC50 of ethanol extract of mangosteen peel in inhibiting the growth of human tongue cancer cells SP-C1. Research carried out on 96 preparations of human tongue cancer SP-C1 were incubated with ethanol extract of mangosteen peel, preparations were classified in two groups of incubation time (24 hours and 48 hours) and each group will be given preferential treatment over 6 randomly different concentrations: 0 (control), 62.5 Î¼g/mL, 125 Î¼g/mL, 250 Î¼g/mL, 500 Î¼g/mL and 1000 Î¼g/mL. Model experiments were 2 x 6 factorial experiment with eight replication for each cell. Test results with ANAVA, incubation (24 and 48 hour) SP-tongue cancer cells with various concentrations of C1 ethanol extract of mangosteen peel gives a highly significant, indicating differences cancer cell growth inhibition. Incubation time factor showed the long incubation effect on cancer cell growth inhibition. Furthermore, by Newman Keuls test, showed 500Î¼g/mL concentrations of 24-hour incubation had the best effect. Conclusion of the study of ethanol extract of mangosteen peel could achieve with IC50 values of cell growth resistance 50.3% at a concentration of 500 Î¼g/mL and an incubation time of 24 hours.

Prevalence of caries in intellectually impaired children at Sekolah Semangat Maju, Taiping, Perak, Malaysia Singh, Sanjit; Sasmita, Inne Suherna
Padjadjaran Journal of Dentistry Vol 21, No 2 (2009): July
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Dental caries also known as tooth decay is a disease where a bacterial process damages the hard tooth structure. The aim of conducting this research was to obtain the prevalence of caries in the intellectually impaired children in Sekolah Semangat Maju, Taiping, Perak, Malaysia. The research was a descriptive research that utilized the survey technique. The population of the research was the students aged 7-17 years old from class 1 to class 5. The total sample for this research was 56 students. The students were examined for the presence of caries and the results were used to obtain the prevalence of caries in these subjects. The results from this study showed that the prevalence of caries based on the studentâs medical diagnose was 68.42% for autism students, 57.14% for cerebral palsy students, 91.67% for Downâs syndrome students, 100.00% for mental retardation students and 42.86% for slow learner students. The conclusion from this research was that the overall prevalence of caries in intellectually impaired children at Sekolah Semangat Maju Taiping, Perak, Malaysia is 67.89%.

Oral manifestations and their management in children undergoing haemodialysis treatment Pertiwi, Arlette Suzy Puspa; Sasmita, Inne Suherna; Gartika, Meirina
Padjadjaran Journal of Dentistry Vol 19, No 3 (2007): November
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Haemodialysis is a medical procedure that artificially filters blood. This procedure is carried out to treat children with end-stage renal disease (ESRD). Although haemodialysis is a lifesaving treatment, it also raises many severe oral manifestations associated with ESDR. Among these are increased hypoplasia, enamel opacities, uremic stomatitis, oral bleeding, increased periodontal disease, reduced salivary flow, xerostomia, and an increased tendency of calculus deposition. This paper will discuss the oral manifestations associated with ESRD and their management in children undergoing haemodialysis treatment.

Craniofacial growth and development of Turner syndrome children Sasmita, Inne Suherna; Pertiwi, Arlette Suzy Puspa; Achmad, M Harun
Padjadjaran Journal of Dentistry Vol 21, No 2 (2009): July
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Turner syndrome is a genetic disorder which characterized by specific physical appearance and the lost of one of sex chromosome in females. The most frequent chromosome constitution in Turner syndrome is 45X. This disorder may cause an interruption of growth and development in the whole body as well as in the craniofacial region. The oral manifestations of Turner syndrome are micrognathia, high palate, malocclusion, and the premature eruption of first permanent molars. This paper will discuss the oral manifestations associated with the craniofacial growth and development of Turner syndrome.

Role of Streptococcus Anginosus on the formation of dental caries Nonong, Yetty Herdiyati; Satari, Mieke Hemiawati; Sasmita, Inne Suherna
Padjadjaran Journal of Dentistry Vol 23, No 3 (2011): November
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Generally, the etiology of dental caries is the cariogenic properties of bacteria, these are always associated with Streptococcus mutans. Glucosyltransferase fragment (Gtf) are also in other strains of Streptococcus such as Streptococcus anginosus, Streptococcus milleri which includes beta hemolysis. Genotypically B Streptococcus anginosus has genetic characteristics that are similar to Streptococcus mutans. The research objective was to determine the existence of Gtf B/C gene as a cause of caries in Streptococcus anginosus. The study was conducted in experimental laboratories with PCR technique by taking a sample of 20 children who had caries. The results showed there was the amplification of Streptococcus anginosus with a level of homology 96%, 97%, and 99%. The results of the Gtf genes amplification fragment B/C provided 600 pb ribbon. The conclusion was Streptococcus anginosus classified as cariogenic bacteria because they had Gtf B/C genes.

Hubungan status ekonomi keluarga dengan resiko karies gigi usia 6-12 tahunRelation of family economic status and dental caries risk of children aged 6-12-years-old Setiawan, Editha Meydiana; Sasmita, Inne Suherna; Riyanti, Eriska
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 28, No 2 (2016): Agustus
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Pendahuluan: Status ekonomi keluarga yang rendah merupakan salah satu faktor prediksi status kesehatan yang buruk. Status ekonomi keluarga yang rendah dikaitkan dengan faktor risiko karies gigi tinggi. Tujuan untuk mengetahui hubungan status ekonomi keluarga dan risiko karies gigi usia 6-12 tahun. Metode: Deskriptif korelasional dengan pengambilan sampel menggunakan multistage random sampling, status ekonomi diklasifikasikan berdasarkan Nielsen Media Research, dan risiko karies diukur dengan caries risk assessment tool (CAT) oleh AAPD. Â Sampel penelitian berjumlah 89 anak berusia 612 tahun yang bersekolah di SDN Ujung Berung, SDN Marga Cinta, SDN Pajajaran, SDN Dadali, dan SDN Sekeloa. Hasil: Menunjukkan bahwa rata-rata responden berstatus ekonomi tinggi yang memiliki risiko karies yang tinggi (22.47%). Perhitungan secara statistik mengunakan uji Wilcoxon Sign Rank Test didapatkan nilai Zhitung= -0,821, dan pvalue = 0,412. Simpulan: Tidak terdapat hubungan status ekonomi keluarga dan risiko karies usia 6-12 tahun.ABSTRACTIntroduction: Low family economic status is one of the factors predicting poor health status. Low family economic status is associated with high dental caries risk factors. The aim is to determine the relationship of family economic status and risk of dental caries aged 6-12 years. Methods: Descriptive correlation with sampling using multistage random sampling, economic status classified according to Nielsen Media Research, and caries risk measured by caries risk assessment tool (CAT) by AAPD. The study sample consisted of 89 children aged 612 years who attended SD Berung, SDN Marga Cinta, SDN Pajajaran, SDN Dadali, and SDN Sekeloa. Results: Shows that the average respondent has a high economic status who has a high caries risk (22.47%). Statistical calculations using the Wilcoxon Sign Rank Test test obtained the value of Zhitung = -0.821, and pvalue = 0.412. Conclusion: There is no relationship between family economic status and caries risk between 6-12 years of age.Keywords: CAT AAPD, caries risk, family economic status.

Hubungan antara status ekonomi keluarga dan risiko karies gigi anak usia 0-3 tahunRelationship between family economic status and dental caries risk of children aged 0-3-years-old Yonathan, Heidy Stefanie; Riyanti, Eriska; Sasmita, Inne Suherna
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 30, No 2 (2018): Agustus
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Pendahuluan: Status ekonomi keluarga merupakan salah satu indikator penting dalam menentukan karies gigi anak usia 0-3 tahun. Penelitian ini bertujuan untuk menganalisis hubungan status ekonomi keluarga dengan risiko karies gigi anak usia 0-3 tahun. Metode: Penelitian ini bersifat analisis korelasional, dengan teknik multi-stage random sampling. Sampel berjumlah 109 anak yang berusia 0-3 tahun di 5 posyandu kota Bandung. Status ekonomi keluarga dan risiko karies gigi diukur dengan skala berdasarkan Nielsen Media Research dan American Academy of Pediatric Dentistryâs Caries-Risk Assessment Tool. Korelasi kedua variabel dianalisis menggunakan Wilcoxon Signed Rank Test. Hasil: Anak yang berasal dari status ekonomi keluarga rendah memiliki risiko karies gigi yang tinggi. Perhitungan statistik menggunakan uji korelasi Wilcoxon Signed Rank Test dengan Î± = 5%, diperoleh nilai koefisien korelasi Zhitung = -8,351 dan signifikansi p-value = 0,000. Simpulan: Terdapat hubungan status ekonomi keluarga dengan risiko karies gigi usia 0-3 tahun.Â ABSTRACTIntroduction: Family economic status is an important indicator in determining dental caries risk in children ages 0-3 years. The aim of this study is to analize the correlation between family economic status and dental caries risk in children ages 0-3 years. Methods: This correlational analitic study used multistage random sampling technique. Family economic status and dental caries risk were measured in 109 children ages 0-3 years, which had been registered at 5 posyandu in Bandung city, according to Nielsen Media Research scale and American Academy of Pediatric Dentistryâs Caries-risk Assessment Tool. The correlation of variables was analyzed using Wilcoxon Signed Rank Test. Result: The children with low family economic status have high dental caries risk. Statistic calculation using Wilcoxon Signed Rank Test with Î± = 5%, showed coefficient correlation Z = -8.315, with significancy p-value = 0.000. Conclusion: There is a correlation between family economic status and dental caries risk ages 0-3 years.Keywords: Caries-risk assessment, dental caries risk, family economic status.

Co-Authors Ananto Ali Hasyimi Anie Apriani Anissa Maya Kania Anissa Maya Kania Arlette Suzy Puspa Pertiwi Astari Miryasandra Bani Gidel Chita Sintya Dewi Debrina Mayasari Soekamto Dela Armilda Dhia Thifal Malihah Dudi Aripin Edi Suanto Edi Suanto, Edi Elih Elih Eriska Riyanti Fadhlil Ulum Abdul Rahman Fahmi Oscandar Fahmi Oscandar, Fahmi Fa``Iqoh Zulfal Majidah Georgiana Marsya Georgiana Marsya, Georgiana Harun Achmad Hilnia Zidnia Ittaqi Tafuzi Kholid Iwan Ahmad Musnamirwan Josevinda Ayu Pramesti Kirana Lina Gunawan Kirana Lina Gunawan Lisda Damayanti Lusi Epsilawati M Harun Achmad, M Harun Meirina Gartika Mieke Hemiawati Satari Mieke Hemiawati Satari Murnisari Dardjan Nadiya Mujaheda Alwafa Nani Murniati Nurwahidah, Sinta Ratna Ayu Alia Zulkarnain Ratna Ayu Alia Zulkarnain, Ratna Ayu Alia Ratna Indriyanti Rine Dianegianty Risti Saptarini Primarti Roosje Rosita Oewen Roosje Rosita Oewen, Roosje Rosita S. Supriatno S. Supriatno, S. Sandy Dwiputra Sanjit Singh Sanjit Singh, Sanjit Septian Rahmat Hidayat Setiawan, Editha Meydiana Sinta Nurwahidah Sri Susilawati Suwondo, Willyanti Syarief Hidayat Unang Supratman Williyanti Suwondo Willyanti Soewondo Willyanti Suwondo Yetty Herdiati Nonong Yetty Herdiyati Yetty Herdiyati Nonong Yetty Herdiyati Nonong, Yetty Herdiyati Yoana Yoana Yonathan, Heidy Stefanie Yurika Ambar Lita Yuti Malinda

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