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All Journal FIKkeS Majalah Kedokteran Gigi Indonesia Dentino: Jurnal Kedokteran Gigi Dental Journal (Majalah Kedokteran Gigi) Journal of Dentomaxillofacial Science E-Prodenta Journal of Dentistry Dentin
Dewi Nurdiana
Department Of Oral Biology, University Of Lambung Mangkurat Banjarmasin, Indonesia
Dentistry Health Professions Medicine & Pharmacology

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PERBANDINGAN SENSITIVITAS LIDAH TERHADAP RASA MANIS DAN PAHIT PADA ORANG MENGINANG DAN TIDAK MENGINANG DI KECAMATAN LOKPAIKAT KABUPATEN TAPIN Sunjaya Tunggala; Nurdiana Dewi; Asnawati Asnawati
Dentino : Jurnal Kedokteran Gigi Vol 1, No 2 (2016)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v1i2.566

Abstract

ABSTRACT  Background:Tongue has taste buds which are consisted of taste receptors. Its sensitivity is influenced by several factors including betel chewing habit. Purpose:This study aimed to identify whether tongue sensitivity of sweet and bitter tastes in betel chewing community was lower compared to non-betel chewing people in Kecamatan Lokpaikat Kabupaten Tapin. Methods:This study was an analytical survey with cross sectional approach. Samples were selected using total sampling method. Total samples were 32 people, classified into 2 groups of 16 women with betel chewing habit and 16 women without betel chewing habit. Both groups were given sucrose solution of 4 different concentrations (0,05; 0,1; 0,2 and 0,4g/mL) to test tongue sensitivity of sweet taste and quinine hydro-chloride solution of 4 different concentrations (0,0004; 0,0009; 0,0024 and 0,006g/mL) to test the bitter taste sensitivity. Result:Results shown provided an average scores of 1.875 ± 0.619 for sweet taste sensitivity and 1.250 ± 1.125 for bitter taste sensitivity in betel chewing community and an average scores of 3.687 ± 0.478 for sweet taste sensitivity and 3.000 ± 0.816 for bitter taste sensitivity in nonbetel chewing people. Mann-Whitney test result of both groups indicated a p-value of (0.000). Conclusion:Based on the results, it could be concluded that tongue sensitivity of sweet and bitter tastes in betel chewing community was lower than non-betel chewing people in Kecamatan Lokpaikat Kabupaten Tapin.  Key Words :tongue sensitivity, tongue,betel chewing  ABSTRAK  Latar Belakang:Lidah memiliki taste buds yang mengandung reseptor rasa. Sensitivitasnya dapat dipengaruhi oleh berbagai macam faktor termasuk kebiasaan menginang.Tujuan:Penelitian ini bertujuan untuk mengetahui apakah sensitivitas lidah terhadap rasa manis dan pahit pada orang menginang lebih rendah daripada orang yang tidak menginang di Kecamatan Lokpaikat Kabupaten Tapin. Metode:Penelitian ini merupakan penelitian survey analitik dengan pendekatan cross sectional. Pengambilan sampel menggunakan teknik total sampling. Sampel berjumlah 32 orang yang dibagi menjadi 2 kelompok yaitu 16 wanita dengan kebiasaan menginang dan 16 wanita tanpa kebiasaan menginang. Kedua kelompok sampel diberi larutan sukrosa dengan 4 konsentrasi berbeda (0,05; 0,1; 0,2 dan 0,4g/mL) untuk menguji sensitivitas rasa manis dan larutan quinine hydro-chloride dengan 4 konsentrasi berbeda (0,0004; 0,0009; 0,0024 dan 0,006g/mL) untuk menguji sensitivitas rasa pahit. Hasil: Hasil penelitian pada orang menginang terhadap rasa manis didapatkan skor rata-rata 1,875±0,619  pada rasa pahit didapatkan skor rata-rata 1,250 ±1,125 dan pada orang  tidak menginang terhadap rasa manis didapatkan skor rata-rata 3,687±0,478 pada rasa pahit didapatkan skor ratarata 3,000 ±0,816. Hasil uji Mann-Whitney pada kedua kelompok menunjukkan nilai p (0,000). Kesimpulan:Berdasarkan hasil penelitian ini dapat disimpukan bahwa sensitivitas lidah terhadap rasa manis dan pahit pada orang menginang lebih rendah daripada orang yang tidak  menginang di Kecamatan Lokpaikat Kabupaten Tapin.  Kata-kata kunci : sensitivitas lidah, lidah, menginang
CARIES RISK EVALUATION USING CARIOGRAM IN MANAGEMENT OF CHILDREN RAMPANT CARIES Nurdiana Dewi; Siti Bale Sri Rantinah; Al Supartinah
Dentino : Jurnal Kedokteran Gigi Vol 3, No 2 (2018)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v3i2.5385

Abstract

Background: The prevalence of rampant caries in children is still high. Management of caries should be done immediately to maintain the function of the teeth. Evaluation of rampant caries management may be performed with the cariogram. Cariogram describes the cause and sequence of caries risk. Objectives: The aim of this case report was to report the results of the evaluation of rampant caries management using cariogram in 6-year-old girls at Pediatric Dentistry Clinic of RSGMP Prof Soedomo. Method: A 6-year-old girl accompanied by her mother reported to Pediatric Dentistry Clinic of RSGMP Prof. Soedomo Faculty of Dentistry UGM with the chief complaint of multiple decayed teeth. Based on anamnesis and clinical examination, it can be concluded that the patient had rampant caries. A cariogram was performed at initial treatment, followed by  DHE and topical application fluor. Treatment was performed by restore 53, 62, 63, 64, 65, 74 and 84 using Glass Ionomer Cement (GIC). Pulpectomy were performed at 75 and 85. Teeth 52 and 54 were extracted. Crown and loop space maintainer was performed to restore 55 and obtain the space of 54. Result: Evaluation of treatment using cariogram was performed at 3rd months and 6th months evaluation. Conclusion: It was concluded that there were decreased in the magnitude of caries risk factors. The highest decreased of risk factors occurred in susceptibility and bacterial factors.
EFEKTIVITAS EKSTRAK IKAN HARUAN (Channa striata) DAN IBUPROFEN TERHADAP JUMLAH SEL NEUTROFIL PADA PROSES PENYEMBUHAN LUKA Studi in Vivo pada Mukosa Bukal Tikus (Rattus norvegicus) Wistar Riski Agustin; Nurdiana Dewi; Suka Dwi Raharja
Dentino : Jurnal Kedokteran Gigi Vol 1, No 1 (2016)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v1i1.424

Abstract

ABSTRACT Background: Wound healing associated with growth and regeneration phenomenon of tissue that consists of four phases, which are inflammatory phase, migration phase, proliferative phase, and remodeling phase. Inflammatory phase takes place in the first 24 hours until day 3 with marked cellular activity. One of the cellular activity is the movement of neutrophils into the blood vessels to the increasing pain in 24-48 hours and decreased after 3rd of day One of the cellular effects of seepage of fluid in the blood vessels and then cause edema.Haruan contains albumin, zinc (Zn), iron (Fe), and fatty acids that have potential to accelerate wound healing process. Purpose:The purpose of this study is to determine the effect of extract Haruan (Channa striata) 25%, 50%, and 100% in wound healing process of buccal mucosa Wistar (Rattus norvegicus) Rats on day 3 by counting the number of neutrophils every treatment groups. Methods: This study was true experimental with posttest-only design with control design. Researcher conducted 5 treatments, there were Aquadest, Haruan extract 25%, 50%, and 100%, and Ibuprofen. Results: The results presented the number of neutrophils in concentration 100% of haruan extract had been most effective reduce neutrophil cells in the wound healing process. Conclusion: Haruan extract (Channa striata) was effective on increasing wound healing process of buccal mucosa Wistar (Rattus norvegicus) Rats characterized by the number of neutrophils which were decrease in acute inflammatory cells histopathologically on day 3. ABSTRAK Latar Belakang: Penyembuhan luka berhubungan dengan fenomena regenerasi jaringan yang terdiri dari empat fase, yaitu fase inflamasi, fase migrasi, fase proliferasi, dan fase remodelling. Fase inflamasi berlangsung pada 24 jam pertama sampai hari ke-3 dengan ditandai adanya aktivitas selular. Salah satu aktivitas selular tersebut adalah pergerakan neutrofil ke pembuluh darah menuju luka yang meningkat pada 24 – 48 jam dan menurun setelah hari ke-3. Salah satu efek selular dari rembesan cairan di pembuluh darah kemudian menyebabkan edema. Ikan Haruan memiliki kandungan yang berperan penting untuk mempercepat proses penyembuhan luka antara lain albumin, mineral seng (Zn), besi (Fe), dan asam lemak. Tujuan: Tujuan penelitian ini adalah mengetahui pengaruh ekstrak Ikan Haruan (Channa striata) 25%, 50%, dan 100% pada proses penyembuhan luka mukosa bukal Tikus (Rattus norvegicus) Wistar pada hari ke-3 dengan menghitung jumlah neutrofil setiap kelompok perlakuan. Metode: Penelitian ini bersifat eksperimental murni dengan rancangan posttest-only with control design. Peneliti melakukan 5 perlakuan, antara lain Aquadest, ekstrak Ikan Haruan 25%, ekstrak Ikan Haruan 50%, ekstrak Ikan Haruan 100%, dan Ibuprofen. Hasil: Hasil penelitian menunjukkan ekstrak Ikan Haruan 100% paling baik membantu menurunkan sel neutrofil pada proses penyembuhan luka. Kesimpulan: Ekstrak ekstrak Ikan Haruan (Channa striata) efektif membantu proses penyembuhan luka mukosa bukal Tikus (Rattus norvegicus) Wistar dengan ditandai penurunan jumlah sel radang akut neutrofil secara histopatologi dilihat pada hari ke-3.
EFEK ANTIBAKTERI SEDIAAN TUNGGAL DAN KOMBINASI AIR PERASAN JERUK NIPIS DAN MADU TERHADAP Streptococcus mutans Kajian In Vitro SediaanTunggal dan Kombinasi Air Perasan Jeruk Nipis dan Madu dengan Klorheksidin Glukonat 0,2% Alfia Fitriani; Nurdiana Dewi; Lia Yulia Budiarti
Dentino : Jurnal Kedokteran Gigi Vol 1, No 2 (2016)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v1i2.561

Abstract

ABSTRACT  Background: Streptococcus mutans is a species of gram positive bacteria dominantly residing in oral cavity and also acts as the most common pathogen causing caries. Lime juice and honey are herbal medicine which has been proven to possess antibacterial effect. Purpose: The aim of this study was to verify that lime juice and honey in combined preparation had more favorable inhibitor potency compared to single preparation against Streptococcus mutans. Methods: This were an experimental study which using random sampling, with 26 treatment groups : 25%, 50%, 75%, 100% lime juice in single preparations and 6,25%, 12,5%, 25%, 50% honey in single preparations, combined preparations of lime juice and honey, also 0,2 chlorhexidin gluconate and aquadest as negative control group. Antibacterial activity test was performed using diffusion method.Result: Data observed showed that there were combined preparations with better inhibitor potency compared to single preparations. Conclusion:One Way ANOVA and LSD tests with confidence interval of 95% presented that antibacterial activity of lime juice and honey in combined preparation was better than its single counterpart against Streptococcus mutans.   Keywords :  antibacterial, lime juice, honey, Streptococcus mutans, inhibition zone  ABSTRAK  Latar Belakang: Streptococcus mutans merupakan salah satu spesies bakteri gram positif yang dominan dalam mulut dan merupakan bakteri penyebab karies patogen paling banyak menyerang manusia. Air perasan jeruk nipis dan madu merupakan tanaman obat yang terbukti mempunyai efek antibakteri.Tujuan: Penelitian ini bertujuan untuk membuktikan bahwa sediaan kombinasi air perasan jeruk nipis dan madu mempunyai daya hambat lebih besar daripada sediaan tunggal dalam menghambat Streptococcus mutans. Metode:Penelitian ini merupakan penelitian eksperimental dengan rancangan acak kelompok yang terdiri dari 26 perlakuan, yaitu sediaan air perasan jeruk nipis konsentrasi 25%, 50%, 75%, 100%, dan madu konsentrasi 6,25%, 12,5%, 25%, 50%, sediaan kombinasinya, serta klorheksidin glukonat 0,2% dan akuades sebagai kontrol negatif. Metode uji aktivitas antibakteri yang digunakan pada penelitian ini adalah metode difusi.Hasil: Data yang didapat menunjukkan bahwa terdapat beberapa perlakuan sediaan kombinasi lebih baik dari sediaan tunggal. Kesimpulan:Hasil uji One Way ANOVA dan LSD dengan tingkat kepercayaan 95% menunjukkan bahwa aktivitas antibakteri sediaan kombinasi air perasan jeruk nipis dan madu lebih baik dari sediaan tunggalnya dalam menghambat pertumbuhan Streptococcus mutans.  Kata-kata kunci : antibakteri, air perasan jeruk nipis, madu, Streptococcus mutans, zona hambat
GAMBARAN DAN PERMINTAAN PASIEN TERHADAP FASYANKES GIGI DI PUSKESMAS KOTA BANJARMASIN Nita Herlina; Nurdiana Dewi; Suka Dwi Raharja
Dentino : Jurnal Kedokteran Gigi Vol 1, No 1 (2016)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v1i1.425

Abstract

ABSTRACT Background: Utilization of dental care facilities by communities are still lacking in Public Health Center of Banjarmasin, but the level of tooth decays are still high. But, patients’ description and demands of dental health facilities in Public Health Center remain unexplored. Purpose: This research aims to identify the description and patients’ demands on dental care facilities in Public Health Center of Banjarmasin. Methode: This was a descriptive study, with sample of patients treated in dental care facilities in 10 Public Health Center of Banjarmasin. Result: The result showed that almost every respondents said that dental care facilities in Public Health of Banjarmasin for this moment were good in the case of health services and fares, and also for the infrastructure which the respondents said mediocre. Whereas, the patients’ demands that said poor or bad was asked the staff to act more polite, friendly, and hospitable, to act faster and more efficiently, also to understand the standard of dental care service. They also demanded more comfortable dental care facilities room, strategic and approachable location, also facilities that is updated and equipped. Conclusion: Based on this conducted research, it can be concluded that there was a few incompatibilities between patients’ demands and health service staff performance alongside the available tools and infrastructures of dental health facilities in Public Health Center of Banjarmasin. ABSTRAK Latar Belakang: Pemanfaatan fasyankes gigi oleh masyarakat di Puskesmas Kota Banjarmasin masih rendah, tetapi tingkat kerusakan gigi masyarakatnya masih cukup tinggi. Namun, gambaran serta permintaan pasien terhadap fasyankes gigi di Puskesmas Kota Banjarmasin masih belum diketahui sampai saat ini. Tujuan: Penelitian ini bertujuan untuk mengetahui gambaran dan permintaan pasien terhadap fasyankes gigi di Puskesmas kota Banjarmasin. Metode: Penelitian ini bersifat deskriptif, dengan sampel berupa pasien yang berobat ke fasyankes gigi di 10 Puskesmas Kota Banjarmasin. Hasil: Hasil penelitian menunjukkan hampir sebagian besar responden berpendapat bahwa gambaran fasyankes gigi di Puskesmas Kota Banjarmasin untuk saat ini sudah baik dalam hal pelayanan petugas kesehatan serta tarif, dan untuk sarana dan prasarana responden berpendapat cukup baik. Sedangkan, untuk permintaan pasien yang berpendapat kurang baik dan tidak baik meminta agar petugas kesehatan gigi bersikap lebih peduli, ramah dan akrab, cepat dan sigap, serta mampu menguasai standar pelayanan kedokteran gigi. Mereka juga meminta ruangan fasyankes gigi yang lebih nyaman, lokasi yang strategis dan mudah dijangkau, serta fasilitas yang diperbarui dan dilengkapi. Kesimpulan: Berdasarkan penelitian yang dilakukan dapat diambil kesimpulan bahwa terdapat sebagian kecil ketidaksesuaian antara permintaan pasien terhadap pelayanan petugas kesehatan serta sarana dan prasarana dengan kondisi yang ada pada saat ini di fasyankes gigi di Puskesmas Kota Banjarmasin.
PENGARUH EKSTRAK SEREH (Cymbopogon citratus) TERHADAP PANJANG LUKA MUKOSA LABIAL MENCIT SECARA KLINIS Melinda Hairi; Nurdiana Dewi; Husnul Khatimah
Dentino : Jurnal Kedokteran Gigi Vol 1, No 2 (2016)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v1i2.574

Abstract

ABSTRACT   Background: Lemongrass is one of the most widely used plants for traditional medicine. Lemongrass has bioactive substances such as phenolic acid, flavonoid, and tannin which act as anti-inflammatory and antioxidant agent which could affect the wound healing process. Purpose: The aim of this study was to assess the effects of 25%, 50%, and 100% lemongrass extract on mice labial mucosa clinical wound length by measuring the wound length. Methods: This study was a true experimental with post test-only with control design. 30 mice were used in this study, which were divided into 5 groups, patent drug containing Aloe vera extract as positive control group, 100% lemongrass extract group, 50% lemongrass extract group, 25% lemongrass extract group, and aquadest as negative control group. Results: One-way ANOVA and Post-hoc LSD tests showed significant difference between Aloe vera extract group, 100% lemongrass extract group, and 50% lemongrass extract group with aquadest group. There was no significant difference between Aloe vera extract group, 100% lemongrass extract group, and 50% lemongrass extract group. There was also no significant difference between 25% lemongrass extract group with aquadest group. Conclusion: Based on the conducted study, it can be concluded that 100% and 50% lemongrass extract could accelerate wound healing process on mice labial mucosa by measuring length of the wound.  Keywords: lemongrass extract, wound healing, wound length, oral mucosa, mice  ABSTRAK   Latar Belakang:Sereh adalah salah satu tanaman yang sering digunakan sebagai obat tradisional.  Sereh mengandung zat bioaktif seperti phenolic acid, flavonoid dan tanin yang berperan sebagai antiinflamasi dan antioksidan yang berpengaruh dalam proses penyembuhan luka.Tujuan:Tujuan penelitian ini adalah untuk mengetahui pengaruh ekstrak sereh 25%, 50%, dan 100% terhadap panjang luka mukosa labial mencit secara klinis dengan mengukur panjang luka. Metode:Penelitian ini merupakan eksperimental murni dengan rancangan post test-only with control design. Penelitian ini menggunakan 30 ekor mencit yang dibagi menjadi 5 kelompok, yaitu kelompok kontrol positif yang menggunakan obat paten mengandung ekstrak Aloe vera, kelompok ekstrak sereh 100%,  kelompok ekstrak sereh 50%, kelompok ekstrak sereh 25%, dan kelompok kontrol negatif menggunakan akuades.Hasil:Hasil uji One-way ANOVA dan Post-hoc LSD menunjukkan perbedaan yang bermakna antara kelompok ekstrak Aloe vera, kelompok ekstrak sereh 100%, dan kelompok ekstrak sereh 50% dibandingkan dengan kelompok akuades. Tidak terdapat perbedaan yang signifikan antara kelompok ekstrak Aloe vera, kelompok ekstrak sereh 100%, dan kelompok ekstrak sereh 50% serta tidak terdapat perbedaan yang signifikan antara kelompok ekstrak sereh 25% dan kelompok akuades.Kesimpulan:Berdasarkan penelitian yang telah dilakukan dapat disimpulkan bahwa ekstrak sereh 100% dan 50% dapat mempercepat penyembuhan luka mukosa labial mencit dilihat dari panjang luka.  Kata-kata kunci:ekstrak sereh, penyembuhan luka, panjang luka, mukosa mulut, mencit
FLAVONOID LEVEL TEST ON ETHANOL EXTRACT OF BINJAI LEAF (Mangifera Caesia) (Research report) Ana Azizah Ansari; Irham Taufiqurrahman; Nurdiana Dewi
Dentino : Jurnal Kedokteran Gigi Vol 4, No 1 (2019)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v4i1.6175

Abstract

Background: Binjai (Mangifera caesia) is a typical plant from South Kalimantan containing secondary metabolites such as flavonoids. Flavonoids possess antioxidant and anti-inflammatory effects that play an important role in wound healing process. Flavonoid compounds isolation from plants can be affected by many factors, one of which is the concentration of solvents. Therefore, determining solvent concentration that can optimally dissolve flavonoids is important. Purpose: The aim of this research was to discover ethanol solvent concentration that can dissolve flavonoid in Binjai leaf optimally. Methods: This study used a true experimental method with posttest-only control group design, using simple random sampling technique, consisting of seven treatment groups which are treatment group P1, P2, P3, P4, P5 and P6 using ethanol concentration of 50%, 60% , 70%, 80%, 90% and 95%, as well as a control group using n-hexane 95% in the process of maceration. Total flavonoids level is calculated using UV-Vis Spectrophotometer.  Results:  Average levels of total flavonoids contained in group P1, P2, P3, P4, P5, P6 and K were 0,025 mg; 0.055 mg; 0.112 mg; 0.068 mg; 0,049 mg; 0,139 mg and 0,026 mg respectively. One way ANOVA test showed significant differences in each group. Post Hoc LSD test revealed that there was no significant difference between 50% ethanol extract groups with 95% n-hexane extract group, whereas the other groups showed significance. Conclusion: The optimal solvent concentration to dissolve flavonoid in Binjai leaf is 95% of ethanol solvents.
Effect of gestational diabetes mellitus on the expression of amelogenin in rat offspring tooth germ Nurdiana Dewi; Ahmad Syaify; Ivan Arie Wahyudi
Dental Journal (Majalah Kedokteran Gigi) Vol. 46 No. 3 (2013): September 2013
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (630.845 KB) | DOI: 10.20473/j.djmkg.v46.i3.p135-139

Abstract

Background: Amelogenin is a major protein constituent of the developing enamel matrix that is critical for enamel formation. Mutations of amelogenin cause hypoplastic enamel phenotypes. Previous research found that infant of diabetic mother has higher risk for having enamel hypoplasia. Purpose: The aim of this study was to determine the effect of gestational diabetes mellitus on the expression of amelogenin in Wistar rats offspring tooth germ. Methods: Sixteen female Wistar rats, aged 2.5-3 months, body weight 150-200 g were used in this study, Wistar rats were mated and divided into two groups and treated on day 0 of pregnancy. Group A was DM group, consisting of 8 rats, induced by streptozotocin (STZ) injection 40 mg/kg BW. Group B was control group, consisting of 8 rats received citrate buffer injection. Thirty-two rat pups were decapitated on day 5. Immunohistochemical procedures were performed on molar tooth germ of the mandibular rat pups using antibody anti-AMELX to determine the expression of amelogenin. Examination carried out on the images using ImageJ software. All data were then statistically analyzed by Mann Whitney test. Results: There was no significant difference in the expression of amelogenin in the DM group and control group (p>0.05). Conclusion: Gestational diabetes mellitus did not affect the expression of amelogenin in rat offspring tooth germ. Further study is needed to examine the pattern of amelogenin expression with measurement of glucose levels of rat pups.Latar belakang: Amelogenin merupakan protein terbanyak pada matriks email yang berperan penting dalam pembentukan email. Mutasi pada amelogenin dapat menyebabkan email menjadi hipoplastik. Penelitian sebelumnya menunjukkan bahwa anak yang dilahirkan oleh ibu pengidap diabetes memiliki resiko lebih tinggi untuk mengalami hipoplasia email. Tujuan: Penelitian ini bertujuan untuk meneliti pengaruh diabetes mellitus gestasional terhadap ekspresi amelogenin pada benih gigi anak tikus Wistar. Metode: Enam belas ekor tikus Wistar betina, umur 2,5-3 bulan, berat badan 150-200 g digunakan dalam penelitian ini, dikawinkan kemudian dibagi menjadi dua kelompok dan diberi perlakuan pada kehamilan hari ke-0. Kelompok A merupakan kelompok diabetes mellitus, terdiri atas 8 ekor tikus diberi perlakuan diabetes mellitus dengan injeksi streptozotocin (STZ) 40 mg/kg BB. Kelompok B merupakan kelompok kontrol, terdiri atas 8 ekor tikus diberi injeksi buffer sitrat. Tiga puluh dua anak tikus yang lahir didekapitasi pada hari ke- 5. Dilakukan prosedur imunohistokimia pada benih gigi molar rahang bawah anak tikus menggunakan antibodi anti-AMELX untuk mengetahui ekspresi amelogenin. Pemeriksaan dilakukan pada hasil foto menggunakan software ImageJ. Hasil kemudian dianalisa menggunakan uji Mann Whitney. Hasil: Tidak terdapat perbedaan yang bemakna pada ekspresi amelogenin kelompok kontrol dan kelompok diabetes mellitus (p>0,05). Simpulan: Diabetes mellitus gestasional tidak mempengaruhi ekspresi amelogenin pada benih gigi anak tikus. Diperlukan penelitian lebih lanjut untuk mengetahui pola ekspresi amelogenin dengan pengukuran kadar glukosa darah anak tikus.
PENGARUH APLIKASI SODIUM FLUORIDE 2% TERHADAP JUMLAH KOLONI Streptococcus sp. DALAM SALIVA ANAK USIA 7-9 TAHUN Zainatun Nadhira; Nurdiana Dewi; Renie Kumala Dewi
Dentin Vol 4, No 3 (2020)
Publisher : Universitas Lambung Mangkurat

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Abstract

ABSTRACTBackground: Dental and oral health problems in Barito Kuala District is caused by wetland area with low acidity. The acidic of land water can support growth of acidogenic and asiduric bacteria that it can reduce pH of oral cavity. Sodium fluoride 2% is one of caries prevention agents because fluoride has antibacterial activity that works by inhibiting enolase enzyme in glycolysis process of oral bacteria. Purpose: To determine effect of 2% Sodium Fluoride on the number of Streptococcus sp. in saliva of children aged 7-9 years in  wetland area. Method: This study used true experimental with pre and post-test with control group design. Twenty subjects selected through simple random sampling and divided into two groups: study group were given  aplication of Sodium Fluoride 2% and control group were not given the application of Sodium Fluoride 2%. Results: Paired t-test results showed a significant difference in p-value (p=0,000) in number of Streptococcus sp. in study group. There was no significant difference in p-value (p=0,056) in the number of Streptococcus sp. in control group. Conclusion: There was an effect of the application of Sodium Fluoride 2% to the number of Streptococcus sp. in saliva of children aged 7-9 years in wetland area. Keywords : Saliva, Sodium Fluoride, Streptococcus sp, Wetlands ABSTRAKLatar Belakang: Masalah kesehatan gigi dan mulut di Kabupaten Barito Kuala disebabkan wilayah tersebut merupakan lahan basah yang memiliki air dengan tingkat keasaman rendah. Sifat asam yang dimiliki air lahan tersebut dapat mendukung pertumbuhan bakteri yang bersifat asidogenik dan asidurik sehingga dapat menurunkan pH rongga mulut. Sodium fluoride 2% adalah salah satu agen pencegahan karies karena fluor memiliki aktivitas antibakteri yang bekerja dengan cara menghambat enzim enolase pada proses glikolisis bakteri rongga mulut. Tujuan: Mengetahui pengaruh Sodium Fluoride 2% terhadap jumlah koloni bakteri Streptococcus sp. dalam saliva anak usia 7-9 tahun pada wilayah lahan basah. Metode: Penelitian ini merupakan eksperimental murni dengan rancangan pre and post-test with control group design. Dua puluh subyek dipilih melalui simple random samling dan dibagi menjadi dua kelompok: kelompok perlakuan yang diberikan aplikasi Sodium Fluoride 2% dan kelompok kontrol yang tidak diberikan aplikasi Sodium Fluoride 2%. Hasil: Hasil uji t-berpasangan menunjukkan ada perbedaan bermakna (p=0,000) pada jumlah koloni Streptococcus sp. pada kelompok perlakuan. Tidak terdapat perbedaan yang bermakna (p=0,056) pada jumlah koloni Streptococcus sp. pada kelompok kontrol. Kesimpulan: Terdapat pengaruh aplikasi Sodium Fluoride 2% terhadap jumlah koloni Streptococcus sp. dalam saliva anak usia 7-9 tahun pada wilayah lahan basah. Kata Kunci : Lahan basah, Saliva, Sodium Fluoride, Streptococcus sp
PERBEDAAN PENGARUH APLIKASI DIFLUOROSILANE 0,9% DAN KOMBINASI SODIUM FLUORIDE 5% DENGAN TRICALCIUM PHOSPHATE TERHADAP JUMLAH KOLONI Streptococcus sp DALAM SALIVA ANAK Naura Ifthinan Luthfiana; Nurdiana Dewi; R. Harry Dharmawan S
Dentin Vol 4, No 3 (2020)
Publisher : Universitas Lambung Mangkurat

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Abstract

ABSTRACTBackground: The high problem of dental and oral health in Barito Kuala Regency affected by its society life that very depending of wetland that has low pH water. The low pH water can cause plaque pH reducing. This condition support Streptococcus sp to produce caries. 0,9% Difluorosilane and 5% Sodium Fluoride with Tricalcium Phosphate combination are the materials that can prevent caries because containing fluor which has antibacterial effects. Fluor works by inhibiting the enolase enzyme in the bacteria glycolysis process. Purpose: To analyze the difference of 0,9% Difluorosilane and 5% Sodium Fluoride with Tricalcium Phosphate combination application effect againts Streptococcus sp colony number in children’s saliva. Methods: This research used the true experiment method with the pretest-posttest with control group design. This research used 15 samples of children’s saliva that divided into 3 groups, that are the 0,9% Difluorosilane application group, the 5% Sodium Fluoride with Tricalcium Phosphate combination application group, and the without treatment group. Results: Post Hoc Bonferroni test result (0,000) (p<0,05) shows that there is a meaningful difference between the three groups. Conclusion: 5% Sodium Fluoride with Tricalcium Phosphate combination can reduce more Streptococcus sp colony number than 0,9% Difluorosilane.Keywords: Difluorosilane, Sodium Fluoride, Streptococcus sp, Tricalcium Phosphate, Wetland ABSTRAKLatar Belakang: Tingginya masalah kesehatan gigi dan mulut di Kabupaten Barito Kuala dipengaruhi oleh kehidupan masyarakat yang sangat bergantung pada lahan basah yang memiliki air dengan pH  rendah. Air dengan pH yang rendah dapat menyebabkan pH plak turun. Keadaan tersebut sangat disukai oleh Streptococcus sp yang dapat menyebabkan karies. Difluorosilane 0,9% dan kombinasi Sodium Fluoride 5% dengan Tricalcium Phosphate merupakan bahan yang dapat mencegah karies karena mengandung fluor yang memiliki efek antibakteri. Fluor bekerja dengan cara menghambat enzim enolase pada proses glikolisis bakteri. Tujuan: Untuk menganalisis perbedaan pengaruh aplikasi Difluorosilane 0,9% dan kombinasi Sodium Fluoride 5% dengan Tricalcium Phosphate terhadap jumlah koloni Streptococcus sp dalam saliva anak. Metode: Penelitian ini menggunakan metode true experiment dengan rancangan pretest-posttest with control group design. Penelitian ini menggunakan 15 sampel saliva anak yang dibagi menjadi 3 kelompok, yaitu kelompok aplikasi Difluorosilane 0,9%, kelompok aplikasi kombinasi Sodium Fluoride 5% dengan Tricalcium Phosphate, dan kelompok tanpa perlakuan. Hasil: Hasil uji Post Hoc Bonferroni (0,000)(p<0,05) menunjukkan terdapat perbedaan yang bermakna antar ketiga kelompok. Kesimpulan: Kombinasi Sodium Fluoride 5% dengan Tricalcium Phosphate dapat menurunkan jumlah koloni Streptococcus sp yang lebih banyak dibandingkan Difluorosilane 0,9%.Kata kunci: Difluorosilane, lahan basah, Sodium Fluoride, , Streptococcus sp, Tricalcium Phosphate
Co-Authors Ahda Ahda Annisa Ahmad Syaify, Ahmad Akhmad Akhdiannoor Ramadhan Al Supartinah Alfia Fitriani Alfia Fitriani, Alfia Amy Nindia Carabelly Ana Azizah Ansari Anita Diana Putri Annisa Rahma Ardi Siswanto Asnawati Asnawati Asnawati Asnawati Aspriyanto, Didit Aulia Azizah Beta Widya Oktiani Debby Saputera, Debby Devi Puspita Handayani Dewi Puspitasari Diana Wibowo Feryra Putri Ayu Suma Feryra Putri Ayu Suma, Feryra Putri Gusti Wina Ayu Hazarisa Haryanto Adi Nugroho Hasvina Sofrullah Hatta, Isnur Hilda Ayu Setyawati Hilda Ayu Setyawati, Hilda Ayu Husnul Khatimah I Wayan Arya Krishnawan Firdaus Ichrom Nahzi, Muhammad Yanuar Ika Kustiyah Oktaviyanti Ika Kusuma Wardani Ivan Arie Wahyudi Khatimah, Husnul Lena Rosida Lena Rosida Lia Yulia Budiarti Lia Yulia Budiarti Lisda Hayatie Maulida Rahmaniah Melinda Hairi Melinda Hairi, Melinda Muhammad Yunanda Anhar Naura Ifthinan Luthfiana Nita Herlina Nita Herlina, Nita Noryunita Rahmah Noryunita Rahmah, Noryunita Phradina Fili Septishelya Raharja, Suka Dwi Rahmad Arifin Renie Kumala Dewi Renita Renita Rahmad Renita Renita Rahmad, Renita Riky Hamdani Riski Agustin Riski Agustin, Riski Rosihan Adhani, Rosihan Salma Humaira Sari, Galuh Dwinta Setyawardhana, Raden Harry Dharmawan Sherli Diana Sinaga, Udur Siti Almira Rahma Siti Bale Sri Rantinah Sonia Dewi Maharani Suka Dwi Raharja Sunjaya Tunggala Sunjaya Tunggala, Sunjaya Tri Putri, Deby Kania Wahyuni A Wahyuni A, Wahyuni Yasmina Aulia Zainatun Nadhira