Article Per Year (5 Year)
p-Index From 2019 - 2024
3.753
P-Index
This Author published in this journals
All Journal Buletin Veteriner Udayana Buletin Udayana Mengabdi Jurnal Veteriner Indonesia Medicus Veterinus Advances in Tropical Biodiversity and Environmental Sciences Jurnal Kedokteran Hewan Journal of Veterinary and Animal Sciences
I Wayan Wirata
Fakultas Kedokteran Hewan Universitas Udayana
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Education Environmental Science Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

Published : 37 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Advances in Tropical Biodiversity and Environmental Sciences

 1 
Kidney Histopathology of Wistar Rats Chronic Apical Periodontitis Luh Made Sudimartini; Anastasia Bhala; I Wayan Wirata; Ni Luh Eka Setiasih; Ni Kadek Eka Widiadnyani; I Made Merdana
Advances in Tropical Biodiversity and Environmental Sciences Vol 6 No 2 (2022): ATBES
Publisher : Institute for Research and Community Services Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/ATBES.2022.v06.i02.p04

Abstract

Chronic apical periodontitis is an inflammatory disease that causes periodontal tissue destruction and forms chronic lesions. This study aims to prove that the administration of green meniran leaf ethanol extract can affect the kidney histopathology of chronic apical periodontitis Wistar rats. This study used a randomized posttest only control group design with four treatment groups and twelve replications of three sub-groups according to the time of application of the medicament paste, namely the 7th, 14th, and 21st days so that 48 Wistar rats were used. The treatment group consisted of negative control (K1), only injected with disease-causing bacteria. The positive control group was given 2% Calcium Hydroxide and Chlorhexidine digluconate. Treatment group 1(P1) was given calcium hydroxide and 10% green meniran leaf ethanol extract, and treatment group 2(P2) was given calcium hydroxide, 2% chlorhexidine digluconate, and 10% green meniran leaf ethanol extract. All samples were male Wistar rats with a weight ranging from 300-350 grams. The variables observed were congestion and necrosis with a score of 0 (normal); 1 (focal); 2 (multifocal); 3 (diffuse). The data were analyzed using the Kruskal-Wallis non-parametric statistical test and if it showed a significant effect, it was continued with the Mann-Whitney test. The results of the Kruskal-Wallis test showed that in the K2, P1, and P2 treatments, there was a significant difference (P<0.05) in the category of congestion and necrosis of the histopathological changes of the kidneys. The results of this study indicate that the ethanol extract of green meniran leaves which has a function as an antioxidant can repair kidney damage caused by free radicals in chronic apical periodontitis conditions
Co-Authors Abd. Rasyid Syamsuri Adigunawan, I Wayan Widya Agatha Serena Lumban Tobing Amelia Avianti Saritjang Anak Agung Gde Jaya Wardhita, Anak Agung Gde Jaya Anak Agung Gde Oka Darmayudha Anak Agung Gde Oka Dharmayudha Anak Agung Jaya Wardhita Anastasia Bhala Andini, Ni Made Ria Antari, Gusti Ayu Made Sri Ayu Ratnasari Deo Lauda Putra Dewi, Kadek Evi Dian Puspita Gunawan, I Wayan Nico Fajar Gunawan, Stefanus Andre I Gusti Agung Gede Putra Pemayun I GUSTI NGURAH DIBYA PRASETYA I Gusti Ngurah Kade Mahardika I Gusti Ngurah Mahardika I Gusti Ngurah Narendra I Gusti Ngurah Narendra Putra I Gusti Ngurah Narendra Putra1, I Gusti Ngurah Sudisma I KADEK SAKA WIRYANA I Ketut Anom Dada I Ketut Berata I Ketut Eli Supartika I Made Kardena I Made Merdana I Made Sukada I MADE SUMA ANTARA I Made Suma Anthara i Nengah Wandia I Nyoman Suartha I Wayan Gorda I Wayan Juli Sumadi I wayan Teguh Wibawan Ida Ayu Sri Chandra Dewi Ida Bagus Kade Suardana Ida Bagus Oka Winaya Iwan Harjono Utama Kadek Karang Agustina Komang Darma Yudha Putra Luh Gde Sri Surya Heryani Luh Made Sudimantini Luh Made Sudimantini Luh Made Sudimartini Made Suma Anthara Maria Clafita Witoko Mildawati Mildawati Ni Kadek Eka Widiadnyani Ni Luh Eka Setiasih Ni Made Rita Krisna Dewi Ni Made Ritha Krisna Dewi Ni Putu Trisna Asih Purbantoro, Steven Dwi Putra, Komang Darma Yudha Putu Henrywaesa Sudipa Rohmandhani, Roby Sasmita, Debbie Aprillia Yona Steven Dwi Purbantoro Steven Dwi Purbantoro Surbakti, Yeyen Fami Gressia Br Tahalli, Tahalli Tessa Saputri Marmanto TRI KOMALA SARI Warditha, Anak Agung Gde Jaya Wayan Herry Gumawan Wulandari Wulandari