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Chitosan Menurunkan Kadar Ferritin Serum dan Deposit Besi Jantung pada Tikus Putih Wistar (Rattus norvegicus) Jantan Model Iron Overload Sari, Febrina; Saleh, Irsan; Hariani, Poedji Loekitowati
Biomedical Journal of Indonesia: Jurnal Biomedik Fakultas Kedokteran Universitas Sriwijaya Vol 3, No 2 (2017)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Kemampuan chitosan untuk mengikat besi dapat diketahui dengan cara mengukur kadar ferritin serum dan deposit besi jantung pada tikus putih wistar (Rattus norvegicus) jantan model iron overload. Metode yang digunakan pada penelitian ini adalah eksperimen laboratorium in vivo. Tiga puluh (30) ekor  tikus wistar jantan dibagi menjadi 6 kelompok, yaitu kelompok normal (N) diberi makanan standar dan tanpa perlakuan tertentu, kelompok control negative (K-) diberi makanan standar dan diinjeksikan iron sucrose 75 mg/KgBB selama lima minggu (3x seminggu) secara intraperitoneal. Kelompok perlakuan terdiri dari P1, P2, P3 diinjeksikan iron sucrose 75mg/kgBB selama lima minggu (3x seminggu) serta diberikan tambahan perlakuan yang berbeda. Selain diberikan makanan standar, kelompok P1 diberikan chitosan secara oral 16 mg/KgBB/hari, kelompok P2 diberikan chitosan secara oral 32 mg/KgBB/hari, sedangkan kelompok P3 diberikan chitosan oral 64 mg/KgBB/hari. Kelompok control positif (K+) pada penelitian ini diinjeksi iron sucrose dan diberikan deferiprone 75mg/KgBB/hari secara oral. Hasilnya menunjukkan bahwa pemberian chitosan 16mg/KgBB/hari yang diberikan secara oral tidak memiliki perbedaan secara signifikan (p>0,05) dari pemberian deferiprone oral dalam menurunkan kadar ferritin serum dan deposit besi jantung.
Influence of the Rubber Seed Type and Altitude on Characteristic of Seed, Oil and Biodiesel Salni, Salni; Hariani, Poedji Loekitowati; Hanifa, Hanifa Marisa
International Journal of Renewable Energy Development Vol 6, No 2 (2017): July 2017
Publisher : Center of Biomass & Renewable Energy, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/ijred.6.2.157-163

Abstract

This research studies the influence of the type of rubber seed that is superior and local, altitude plant in South Sumatra province to the characteristic of seed, oil and biodiesel (methyl ester). Rubber plants planted from local rubber seed by seeds seedlings and superior rubber seed by selected clones. In the study, rubber plants planted at a different altitude, namely in Banyuasin district (18 m above sea level), Prabumulih District (176 m above sea level) and Lahat District (627 m above sea level). The results showed that the weight of the flour, the water content and ash content in the local rubber seeds larger than the superior rubber seed for all altitude, but oil content a large in the superior rubber seeds. The major of fatty acids in the rubber seed oil in all types and altitude are a linoleic acid with a different percentage except local rubber seed oil from Lahat district with the large percentage of octadecanoic acid. Free fatty acids in the oil from the superior seeds rubber of 13.897-15.494 % large than local rubber seed oil was found 9.786-10.399 % for all altitude. By esterification process using sulfuric acid catalyst, Free Fatty Acid (FFA) can be reduced to ≤ 2 %. The methyl ester made from the transesterification process of rubber seed oil after esterification using methanol and sodium hydroxide as catalyst. Analysis of methyl esters includes cetane index, flash point, kinematic viscosity, carbon residue, density, moisture content, water and sediment content and distillation compared with SNI 7182 and ASTM 6751-02.  The result indicated that the quality of methyl ester from superior rubber seed oil in the Banyuasin and Prabumulih district better than another methyl ester. The types of rubber seed altitude affect the characteristics of the seed, oil and methyl ester  but the altitude are not significantly different.Keywords: rubber seed, type, altitude, oil, biodieselArticle History: Received March 21st 2017; Received in revised form May 5th 2017; Accepted June 2nd 2017; Available onlineHow to Cite This Article: Salni, S, Hariani, P.L. and Marisa, H. (2017) Influence the Rubber Seed Type and Altitude on Characteristic of Seed, Oil and Biodiesel. International Journal of Renewable Energy Development, 6(2), 157-163.https://doi.org/10.14710/ijred.6.2.157-163
Chitosan Menurunkan Kadar Ferritin Serum dan Deposit Besi Jantung pada Tikus Putih Wistar (Rattus norvegicus) Jantan Model Iron Overload Febrina Sari; Mgs. Irsan Saleh; Poedji Loekitowati Hariani
Biomedical Journal of Indonesia Vol. 3 No. 2 (2017): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

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Abstract

Kemampuan chitosan untuk mengikat besi dapat diketahui dengan cara mengukur kadar ferritin serum dan depositbesi jantung pada tikus putih wistar (Rattus norvegicus) jantan model iron overload. Metode yang digunakan padapenelitian ini adalah eksperimen laboratorium in vivo. Tiga puluh (30) ekor tikus wistar jantan dibagi menjadi 6kelompok, yaitu kelompok normal (N) diberi makanan standar dan tanpa perlakuan tertentu, kelompok controlnegative (K-) diberi makanan standar dan diinjeksikan iron sucrose 75 mg/KgBB selama lima minggu (3x seminggu)secara intraperitoneal. Kelompok perlakuan terdiri dari P1, P2, P3 diinjeksikan iron sucrose 75mg/kgBB selama limaminggu (3x seminggu) serta diberikan tambahan perlakuan yang berbeda. Selain diberikan makanan standar,kelompok P1 diberikan chitosan secara oral 16 mg/KgBB/hari, kelompok P2 diberikan chitosan secara oral 32mg/KgBB/hari, sedangkan kelompok P3 diberikan chitosan oral 64 mg/KgBB/hari. Kelompok control positif (K+) padapenelitian ini diinjeksi iron sucrose dan diberikan deferiprone 75mg/KgBB/hari secara oral. Hasilnya menunjukkanbahwa pemberian chitosan 16mg/KgBB/hari yang diberikan secara oral tidak memiliki perbedaan secara signifikan(p>0,05) dari pemberian deferiprone oral dalam menurunkan kadar ferritin serum dan deposit besi jantung.
Analisis Mutu Minyak Biji Ketapang (Terminalia Catappa Linn.) Hasil Sokletasi Poedji Loekitowati Hariani; Fahma Riyanti; Heni Oktaviani
Jurnal Penelitian Sains Vol 10, No 3 (2007)
Publisher : Faculty of Mathtmatics and Natural Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5938.335 KB) | DOI: 10.56064/jps.v10i3.454

Abstract

Penelitian tentang “Analisis Mutu Minyak Biji Ketapang (Terminalia catappa L.) Hasil Sokletasi” telah dilakukan. Penelitian ini bertujuan untuk menentukan lama ekstraksi minyak terbaik dari biji Ketapang dengan pelarut n-heksana pada temperatur 70°C dengan variasi waktu ekstraksi (10 jam; 12,5 jam dan 15 jam), kemudian dilakukan uji mutu minyak dan sifat fisika kimia berdasarkan Standar Nasional Indonesia dengan menggunakan parameter uji kadar air, berat jenis, viskositas, bilangan penyabunan, bilangan peroksida dan bilangan asam. Hasil penelitian menunjukkan bahwa lama ekstraksi terbaik minyak dari biji ketapang dengan menggunakan pelarut n-heksana pada temperatur 70°C adalah selama 15 jam. Minyak yang dihasilkan pada kondisi tersebut telah memenuhi Standar Nasional Indonesia dimana dihasilkan berat jenis 0,906 g/mL, viskositas 0,144 poise, bilangan asam 1,862 mg KOH/g minyak, bilangan peroksida 1,985 meq/1000 g minyak dan bilangan penyabunan 184,903 mg KOH/g minyak.
Penurunan Konsentrasi Cr(VI) Dalam Air Dengan Koagulan FeSO4 Poedji Loekitowati Hariani; Nurlisa Hidayati; Melly Oktaria
Jurnal Penelitian Sains Vol 12, No 2 (2009)
Publisher : Faculty of Mathtmatics and Natural Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (424.731 KB) | DOI: 10.56064/jps.v12i2.180

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Telah dilakukan penelitian untuk menurunkan kadar kromium dalam air dengan menggunakan koagulan FeSO4. Parameter yang diteliti adalah pH, konsentrasi koagulan dan waktu kontak optimum. Pengukuran kadar ion kromium pada semua perlakuan ditentukan dengan metode Spektrofotometri Serapan Atom (SSA). Hasil penelitian menunjukkan kondisi optimum koagulasi pada pH 8 dengan konsentrasi koagulan FeSO4 140 mg/L dan waktu kontak 60 menit dapat menurunkan konsentrasi ion kromium 100 % dari konsentrasi ion kromium awal 20 mg/L.
Pelatihan Pembuatan Hand Sanitizer Cair dari Ekstrak Kulit Jeruk Nipis di Kawasan Wisata Desa Burai Poedji Loekitowati Hariani; Fatma Fatma; Muhammad Said; Risfidian Mohadi; Salni Salni
Jurnal Gema Ngabdi Vol. 4 No. 1 (2022): JURNAL GEMA NGABDI
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jgn.v4i1.225

Abstract

Burai village is located in Tanjung Batu sub-district, Ogan Ilir district. Burai Village is a tourism mainstay village in Ogan Ilir district. This village is known as the colorful village. As an ecotourism destination, water tourism and fishing programs have been developed, as well as environmentally friendly fish farming through organic feed. Other tourism potentials, such as the existence of traditional Bari houses that are more than 200 years old, and songket crafts. As patients with the COVID-19 virus have decreased, the number of tourists visiting Burai village has also increased. Health protocols are still needed, one of which is the use of hand sanitizer. This community service activity is to provide training on making liquid hand sanitizer from lime peel extract with the target audience being the Burai village community, especially tourism service providers. Lime plant is one of the plants cultivated by the people of Burai village. Orange peel extract contains essential oils that function to inhibit the growth of bacteria. In addition, orange peel extract has a fresh aroma. Activities are carried out by giving lectures, training on making hand sanitizers and packaging them. With this activity, it is hoped that the community will be able to provide hand sanitizers for both their own needs and tourists. The results of the activity showed high community participation in activities, more than 75% of the target audience liked the aroma of lime peel extract hand sanitizer.
Alumina-Activated Carbon Composite as Adsorbent of Procion Red Dye from Wastewater Songket Industry Poedji Loekitowati Hariani; Fatma Fatma; Zulfikar Zulfikar
The Journal of Pure and Applied Chemistry Research Vol 4, No 1 (2015)
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (863.408 KB) | DOI: 10.21776/ub.jpacr.2015.004.01.206

Abstract

Alumina-activated carbon composite has been synthesized and studied for adsorption procion red dye. Composite was prepared by precipitation method aluminium hydroxide on the surface of activated carbon followed by calcinations. The Fourier transform Infra Red (FTIR), Scanning Electron Microscopy-Energy Dispersive X-Ray Spectroscopy (SEM-EDS) and Brunaeur Emmet Teller (BET) surface are being used to characterize the adsorbent. Batch adsorption experiments were carried out for the adsorption of procion red dye. Effect of the mass of composite, stirrer speed, contact times and pH of the solution on the adsorption capacity were studied. The obtained optimum conditions applied to adsorp of procion red dye from wastewater songket industry. The result showed that the adsorption optimum at mass of alumina-activated carbon composite 0.1 g, stirrer speed 150 rpm, contact times 2 hours at pH of the solution 9. The adsorption isotherm data according to Langmuir isotherm. The alumina-activated carbon composite can be removal of procion red dye from wastewater songket industry with effectiveness adsorption of 88.21 %.
Effect of Calcination Temperature on The Synthesis of Silica from Bagasse Poedji Loekitowati Hariani; Fahma Riyanti; Desneli Desneli; Fatma Fatma; Sabila Yunita; Muhammad Said
The Journal of Pure and Applied Chemistry Research Vol 10, No 2 (2021): Edition May-August 2021
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jpacr.2021.010.02.587

Abstract

Bagasse is the solid waste derived from the sugar-making process. A large amount of silica in bagasse is a potential source of silica. In this study, extraction of silica from bagasse was carried out in the following steps: pretreatment of bagasse using HCl solution, followed by calcination at varying temperatures (700℃, 800℃, and 900℃) using a furnace. Furthermore, extraction using NaOH solution and precipitation using HCl. Silica characteristics were obtained using X-Ray Diffraction (XRD), Scanning Electron Microscopy-Electron Dispersive Spectrometry (SEM-EDS), and BET surface area. The results showed that calcination temperature affected the characteristics of the silica produced. The silica extracted at 700℃ produced an amorphous phase with a broad peak at an angle of 2θ = 20-24°. It contained the most considerable silica content and surface area, 42.46% and 796.89 cm2/g, respectively. The extracted silica had an average diameter of 5.67 mm and a pore volume of 1.184 cm3/g.
Synthesis and Characterization of Fe3O4 Nanoparticles Modified with Polyethylene Glycol as Antibacterial Material Poedji Loekitowati Hariani; Desnelli Desnelli; Fatma Fatma; Rizki Indah Putri; Salni Salni
The Journal of Pure and Applied Chemistry Research Vol 7, No 2 (2018): Edition May-August 2018
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (964.85 KB) | DOI: 10.21776/ub.jpacr.2018.007.02.393

Abstract

The iron oxide (Fe3O4) nanoparticles modified with polyethylene glycol (PEG) was synthesized by co-precipitation methods using ferric and ferrous ions as the precursors. Further, the antibacterial activity was performed against gram-positive and gram-negative bacteria. The Fe3O4-PEG was characterized using X-Ray Diffraction (XRD), Fourier Transform Infra Red (FTIR), Scanning Electron Microscopy (SEM) with energy dispersive X-Ray analysis (EDAX) and Vibrating Sample Magnetometer (VSM). The particle size of Fe3O4-PEG calculated using XRD is 46.2 nm. The study confirmed that Fe3O4-PEG is superparamagnetic and has a saturation magnetization of 56.43 emu/g. The prepared Fe3O4-PEG gives the effect of both gram-positive and gram-negative pathogenic bacterial strains hence this material has potential utilization in the field of pharmaceutical and biomedical in the future. 
Preparation and Characterization Nanoparticle Calcium Oxide from Snakehead Fish Bone using Ball Milling Method Muryati Muryati; Poedji Loekitowati Hariani; Muhammad Said
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 4, No 3 (2019): October 2019
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v4.i3.111

Abstract

Snakehead Fish Bone (SFB) is a waste from food processing in Palembang. Fish bones have calcium content so they have a potential as a source of Calcium Oxide (CaO). Calcination of fish bones was carried out at a temperature of 900oC with variations of time 1, 2, 3, and 4 hours. The Nanoparticle Calcium Oxide (NCO) was prepared using the ball milling method. This study aims to make NCO as a raw material for hydroxyapatite synthesis. The NCO was characterized using Fourier Transform Infra-Red (FTIR), X-Ray Diffraction (XRD), and Scanning Electron Microscope (SEM). Characterization using FTIR shows that NCO has functional groups O-H, CO32- and PO43- functional groups. XRD analysis shows that NCO has an average particle size of 38.9445 nm.Analysis using SEM shows particles in the form of granules of almost uniform size. The NCO produced eligible of the nanomaterial and has the potential as a raw material for synthesis of hydroxyapatite.Keywords: Nanomaterial, ball milling, calcium oxide, fish bone