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Siti Maimunah

Program Studi D3 ANAFARMA, Universitas Sari Mutiara Indonesia

Author-ID : 3483822

Medicine & Pharmacology

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PENGGUNAAN EKSTRAK KULIT BUAH NAGA MERAH (Hylocereuscostaricensis (F.A.C. Weber) Britton & Rose.) DALAM FORMULASI PEWARNA RAMBUT Cut Masyithah; Siti Maimunah; Zuhairiah Zuhairiah; Cahaya Amalia Sitorus
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Hair is a symbol of beauty in humans which is one of the adnexa (parts) of the skin that grows from the skin. Hair grows from the root, hair that is in the dermis layer, and through the hair follicle channel out of the skin. There are some differences in each hair such as type, shape, amount, and color. Dragon fruit peel is an agricultural waste that contains high anthocyanin natural dyes. Anthocyanin is a dye that plays a role in giving red color which has the potential to be a natural colorant for food and can be used as an alternative to synthetic dyes that are safer for health. Anthocyanin was taken by the extraction method. The results showed that the higher the concentration of the adjuvant used, the darker the gray hair. The use of auxiliary materials in a concentration of 0.5% produces a brownish-black color, and a concentration of 1% produces a dark black color. The preparation of gray hair dye made with the formula of 2.5% dragon fruit peel extract and 1% adjuvant produces a deep black color, so pyrogallol, copper (II) sulfate, xanthan gum with a concentration of 0.5% are used in order to distinguish changes on white hair (grey), due to the EKBN formula or from added additives.

UJI AKTIVITAS ANTIBAKTERI HAND SANITIZER DARI EKSTRAK ETANOL BUNGA ROSELLA (Hibiscus Sabdariffa L) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Adiansyah Adiansyah; Siti Maimunah; Elly Nurita Sitorus; Nurul Hazlinda
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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In Indonesia with a tropical climate, rosella can thrive. Roselle plant (Hibiscus sabdariffa L.) is well known for its petals which can be used as a health drink that can cure various diseases. Roselle flower (Hibiscus sabdariffa L.) contains nutritious substances such as alkaloids, flavonoids, tannins, terpenoids, which have antibacterial properties. The purpose of this study was to determine the antibacterial hand sanitizer ethanol extract of Rosella flower (Hibiscus sabdariffa L) had good quality and stability against Staphylococcus aureus bacteria. This research was experimental, including rosella flower sample collection, simplicia drying, extract making using a rotary evaporator, phytochemical screening, characteristics of the antibacterial activity test preparation of hand sanitizer with agar diffusion method using paper discs. Roselle flower ethanol extract can be made as Hand sanitizer in spray preparations and has antibacterial activity. The difference in the concentration of the ethanol extract is 2.5%, the inhibition zone is 6.8 mm, 5% is the inhibition zone is 7.27 mm, 7.5% is the inhibition zone is 7.72 mm and 10% is 12.35 mm. The ethanolic extract of the Roselle flower (Hibiscus sabdariffa L) can be used as a hand sanitizer preparation. It has antibacterial activity against Staphylococcus aureus bacteria and is the most effective at a concentration of 10% of 12.35 mm.

IDENTIFIKASI CEMARAN LOGAM Sn (TIMAH) DALAM SUSU KENTAL MANIS KEMASAN KALENG Siti Maimunah; Yettrie Simarmata; Dina Riani Purba
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Condensed milk or more commonly sweetened condensed milk is cow's milk in which the water is removed and sugar is added, resulting in milk that is very sweet in taste and can last for up to a year if not opened. In general, the term sweetened condensed milk means sweetened milk, namely milk in the form of a thick liquid, yellowish-white or other colors depending on the aroma added, with a distinctive smell and taste. This research was conducted to determine the presence or absence of metallic Sn (tin) in canned sweetened condensed milk in whole and dented cans. The samples examined were whole and dented canned sweetened condensed milk sold around Jalan Kapten Muslim Medan, the samples were taken randomly from three different brands. This study used a qualitative test method, the sample was ashed first using 0.1N HCl solvent, this research was carried out using 0.1N sodium hydroxide reagent there was no white or negative precipitate, using 0.1N sodium carbonate reagent there was no white precipitate or negative. Sweetened condensed milk sold around Jalan Kapten Muslim Medan does not contain Sn (tin) in the qualitative test, this shows that the sweetened condensed milk is safe for consumption.

PEMERIKSAAN KADAR ASAM MERKAPTOASETAT DALAM SEDIAAN PENGERITING RAMBUT YANG BEREDAR DI SALON SEKITAR UNIVERSITAS SARI MUTIARA INDONESIA Siti Nurbaya; Siti Maimunah; Kesaktian Manurung; Risda Hernidawati Nainggolan
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Cosmetics used for this purpose, such as curling hair, use hair curling preparations containing mercaptoacetic acid. Curling hair aims to change the structure of straight hair into wavy. The purpose of this study was to determine the levels of mercaptoacetic acid in hair curling preparations circulating in salons around Sari Mutiara University, Indonesia. The research was conducted on 3 types of samples determined by iodometric titration method using potassium iodide titer solution and starch indicator. The results of this study examined the levels of mercaptoacetic acid in hair curling preparations in samples A: 5,676%, B: 6,053%, C: 6,478%. These results indicate that the 3 types of samples meet the requirements in accordance with the decision of the POM RI No. HK.00.05.42.1018 the Year 2008 with a maximum level of 8.0%.

FORMULASI SEDIAAN ANTISEPTIK DARI BUAH RIMBANG (Solanum torvum) SEBAGAI HAND SANITIZER Siti Maimunah; Yettrie Simarmata; Eka Margaret Sinaga; Kristini Siboro
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Rimbang fruit (Solanum torvum) has properties as a skin antiseptic. Rimbang fruit extract (Solanum torvum) which has been isolated has antibacterial activity against Staphylococcus aureus bacteria. This is because the Rimbang fruit extract (Solanum torvum) contains compounds such as solasonins, glucosides, saponins, and sterolins. Formulation and testing of antibacterial activity of hand sanitizer gel preparations of Rimbang fruit extract and evaluation of the physical quality of hand sanitizer preparations. Rimbang fruit extract was made by the maceration method using 70% ethanol. Then it was evaporated using a rotary evaporator and the remaining solvent was evaporated until a thick extract was formed. Testing of antibacterial activity by agar diffusion method using disc paper against Staphylococcus aureus by measuring the diameter of the zone of inhibition of bacterial growth. The concentration of Rimbang fruit extract and hand sanitizer gel formula used (F1) 0.5% and (F2) 1%; Evaluation of the physical quality of the hand sanitizer preparation includes organoleptic test, homogeneity test, and pH test. The results of the antibacterial activity test of Rimbang fruit extract against Staphylococcus aureus at a concentration of 0.5% with an inhibitory diameter of 5.2 mm. Meanwhile, the results of the gel hand sanitizer activity test of Rimbang fruit extract obtained the inhibition of Staphylococcus aureus bacteria at a concentration of 1% with a diameter of 9.0 mm.

PENETAPAN KADAR PROTEIN DALAM SUSU FORMULA BAYI DAN ASI DI MEDAN SECARA KJELDAHL Eka Margaret Sinaga; Siti Maimunah; Erly Sitompul
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Breast milk (ASI) is the best food for babies. Breast milk has advantages compared to other milk, including guaranteed cleanliness, the composition of breast milk is also very suitable for digestion, growth, and development of babies, one of the compositions contained in breast milk is protein. Currently, many mothers cannot breastfeed their own babies, so they choose infant formula as a substitute for breast milk. The purpose of this study was to determine differences in protein levels in infant formula and breast milk. Determination of protein content was carried out using the Kjeldahl method which is a simple method for determining total nitrogen in protein and other nitrogen-containing compounds. The Kjeldahl method is carried out through 3 processes, namely: the destruction process, the distillation process, and the titration process according to the procedures and tools used in the Chemistry Laboratory of the Sari Mutiara Indonesia University. The results of the determination of protein levels using the Kjeldahl method contained a protein with average levels in infant formula brand A (10.10 ± 0.96) %, infant formula brand B (10.95 ± 2.43) %, infant formula brand C (11.0666 ± 1.6932) %, and breast milk (20.5733 ± 3.1828) %.

ANALISIS TIMBAL (Pb) DAN KADMIUM (Cd) PADA KERANG BULUYANG DIPEROLEH DARI PASAR SEI SIKAMBING MEDAN SECARA KUALITATIF Siti Maimunah; Artha Yuliana Sianipar; Zuhairiah Zuhairiah; Setiawati Gea
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Shellfish (Anadaraantiquata) is one type of shellfish that has the potential to be used as a food source in fulfilling the nutrition of the Indonesian people. Feather clams (Anadaraantiquata) belong to the class Bivalvia which are edible and have economic value. The purpose of this study was to determine the content of lead and cadmium in feather shells. Samples were taken from two fur shell traders at the Sei Sikambing market in Medan using a random sampling method with qualitative testing using disodium sulfide, potassium iodide, potassium chromate, potassium cyanide, and sodium hydroxide reagents, in accordance with work procedures. used in the Medan Regional Health Laboratory. The results showed that of the two samples tested, both samples did not contain lead (Pb) and cadmium (Cd). Keywords: Feather shells, lead (Pb), Cadmium (Cd), Qualitative.

PENETAPAN KADAR ETANOL PADA TAPE SINGKONG (Manihot utilissima) DENGAN PENAMBAHAN SARI BUAH NANAS (Ananas comosus) Siti Nurbaya; Siti Maimunah; Zuhairiah Zuhairiah; Ika Kristina
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Cassava tape is a tape made from fermented cassava. The fermentation process is one way to turn food into the product we want by using microbes. This study aims to determine the effect of adding pineapple juice (Ananas comosus) to the ethanol content of cassava tape (Manihot utilissima). Experimental research method with distillate examination, in the distillation process. The sample used was cassava tape (Manihot utilissima) with variations in the volume of addition of pineapple juice (Ananas comosus) 50 ml, 60 ml, and 70 ml, with a fermentation time of 3 days. The sampling technique used is purposive sampling. The results of weighing the ethanol content with a pycnometer will be matched based on its specific gravity. The results of the study of ethanol levels in cassava tape (Manihot utilissima) with a volume variation of the addition of 50 ml of pineapple juice (Ananas comosus) obtained 2.71% results, with the addition of 60 ml the results were 3.19%, with the addition of 70 ml the results were 3.88%. Meanwhile, the ethanol content of cassava tape (Manihot utilissima) without pineapple juice (Ananas comosus) was found to be 1.88%. The conclusion of this study was that the ethanol content of cassava tape (Manihot utilissima) with the addition of pineapple juice (Ananas comosus) increased.

AKTIVITAS PENGHAMBAT ENZIM PROTEASE 6LU7 VIRUS SARS-COV-2OLEH SENYAWA DARI SPONGE(Filum Porifera) SECARA IN SILICO Kesaktian Manurung; Siti Maimunah; Fitri Yulia Sari
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (614.559 KB)

The metabolite content in sponge has a unique chemical structure and very interesting pharmacological activity, such as anticancer, antimicrobial, anti-inflammatory, antifouling, antifouling, and inhibiting enzyme activity. The purpose of this study is to find out the value of RMSD in protein validation 6LU7 in silico, to know the ability of Sponge compounds in inhibiting protease enzyme 6LU7 from SARS-CoV-2 Virus in silico, and to know the comparison of the results of docking score of Sponge compounds in the inhibition of protease enzyme 6LU7SARS-CoV-2 virus to visualize docking results to know the amino acids that bond with each other. This research is a descriptive study that is to test the activity of Sponge compounds against inhibition of protease enzyme 6LU7 SARS-CoV-2. The phases in this study include downloading and installation applications needed. And validation of in silico tethering method to protease enzyme 6LU7 SARS-CoV-2 virus, as well as the docking of Sponge compound molecules against protease enzyme 6LU7 SARS-CoV-2 virus in silicon. The results of the study obtained that the process of tethering protease enzyme 6LU7 sars-cov-2 virus is declared valid so that it can be used for molecular tethering of Sponge test compounds in silico. Sponge test compounds can inhibit the protease enzyme 6LU7 Sars-CoV-2 virus. The docking score of Sponge test compounds on protease enzyme 6LU7 SARS-CoV-2 virus is lower than the comparison. As the result of docking visualization, several amino acid residues interact with each other including hydrogen bonds.

FORMULASI SEDIAAN KRIM DEODORANT EKSTRAK ETANOL DAUN BELUNTAS (Plucea indica Less.) SEBAGAI PENCEGAH BAU BADAN Eka Margaret Sinaga; Supartiningsih Supartiningsih; Siti Maimunah; Nikmat Jayadi
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (416.965 KB)

Beluntas is one of the plants that is often used as traditional medicine. Beluntas leaves have antimicrobial activity against various kinds of bacteria. This study aims to formulate Beluntas leaf extract (Plucea indica Less.) in the form of a deodorant cream that functions as a deterrent to body odor. The research method was carried out experimentally which included extract preparation, formulation using Beluntas leaf extract (Plucea indica Less.) with a concentration of 5%, 7.5%, 10%, preparation quality test, and hedonic test. The results of the formula The deodorant cream preparation can be used properly and can prevent sweating for 8 hours and the deodorant cream does not cause irritation and provides comfort when used, from formulas 1, 2, and 3, all the results are good to prevent sweating in the armpits but, the formula favored by the volunteers was formula 1 because the aroma was just right unlike formula 2, and formula 3 which had a slightly more pungent aroma, and similarly to the color in formula 1, the color was light green, unlike formula 2, and formula 3 which tended to be lighter in color. dark green. Beluntas leaf ethanol extract can be used to prevent body odor, and the extract can be used as a natural deodorant cream to prevent body odor.

Co-Authors Adiansyah Adiansyah Ahmad Hafizullah Ritonga Arifin Hulu Artha Yuliana Cahaya Amalia Sitorus Cut Masyithah Cut Masyithah Thaib Devina Chandra Dina Riani Purba Eka Margaret Sinaga Eka Margaretha Sinaga Elly Nurita Sitorus Elly Sitorus Erly Sitompul Fitri Yulia Sari Icha Wahyuni Turnip Ika Kristina Jon Kenedy Marpaung Karnerius Harefa Karnerius Harefa Kesaktian Manurung Kristini Siboro Maringan Silitonga Nikmat Jayadi Nurul Hazlinda Pandapotan Nasution Rifka Gloria Risda Hernidawati Nainggolan Sarah Lestari Setiawati Gea Sianipar, Artha Yuliana Siti Nurbaya Supartiningsih Supartiningsih Supartiningsih Supartiningsih Surfin Putri Yanti Yettrie Simarmata Yosy Cinthya Eriwaty Silalahi Yosy Cinthya Eriwaty Silalahi Zuhairiah Zuhairiah

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