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Siti Maimunah
Program Studi D3 ANAFARMA, Universitas Sari Mutiara Indonesia
Medicine & Pharmacology

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FORMULASI SEDIAAN ANTISEPTIK DARI BUAH RIMBANG (Solanum torvum) SEBAGAI HAND SANITIZER Siti Maimunah; Yettrie Simarmata; Eka Margaret Sinaga
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v5i2.2738

Abstract

Rimbang fruit (Solanum torvum) has properties as a skin antiseptic. Rimbang fruit extract (Solanum torvum) which has been isolated has antibacterial activity against Staphylococcus aureus bacteria. This is because the Rimbang fruit extract (Solanum torvum) contains compounds such as solasonins, glucosides, saponins, and sterolins. Formulation and testing of antibacterial activity of hand sanitizer gel preparations of Rimbang fruit extract and evaluation of the physical quality of hand sanitizer preparations. Rimbang fruit extract was made by the maceration method using 70% ethanol. Then it was evaporated using a rotary evaporator and the remaining solvent was evaporated until a thick extract was formed. Testing of antibacterial activity by agar diffusion method using disc paper against Staphylococcus aureus by measuring the diameter of the zone of inhibition of bacterial growth. The concentration of Rimbang fruit extract and hand sanitizer gel formula used (F1) 0.5% and (F2) 1%; Evaluation of the physical quality of the hand sanitizer preparation includes organoleptic test, homogeneity test, and pH test. The results of the antibacterial activity test of Rimbang fruit extract against Staphylococcus aureus at a concentration of 0.5% with an inhibitory diameter of 5.2 mm. Meanwhile, the results of the gel hand sanitizer activity test of Rimbang fruit extract obtained the inhibition of Staphylococcus aureus bacteria at a concentration of 1% with a diameter of 9.0 mm.
ANALISIS TIMBAL (Pb) DAN KADMIUM (Cd) PADA KERANG BULUYANG DIPEROLEH DARI PASAR SEI SIKAMBING MEDAN SECARA KUALITATIF Siti Maimunah; Artha Yuliana Sianipar; Zuhairiah Zuhairiah; Yosy Cinthya Eriwaty Silalahi
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2748

Abstract

Shellfish (Anadaraantiquata) is one type of shellfish that has the potential to be used as a food source in fulfilling the nutrition of the Indonesian people. Feather clams (Anadaraantiquata) belong to the class Bivalvia which are edible and have economic value. The purpose of this study was to determine the content of lead and cadmium in feather shells. Samples were taken from two fur shell traders at the Sei Sikambing market in Medan using a random sampling method with qualitative testing using disodium sulfide, potassium iodide, potassium chromate, potassium cyanide, and sodium hydroxide reagents, in accordance with work procedures. used in the Medan Regional Health Laboratory. The results showed that of the two samples tested, both samples did not contain lead (Pb) and cadmium (Cd). Keywords: Feather shells, lead (Pb), Cadmium (Cd), Qualitative.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN KERSEN (Muntingia calabura L.) TERHADAP BAKTERI Staphylococcus aureus dan Methicillin-Resistant Staphylococcus aureus Siti Maimunah; Karnerius Harefa; Artha Yuliana; Ahmad Hafizullah Ritonga; Arifin Hulu
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2757

Abstract

Kersen (Muntingiacalabura L) is one of the wild plants that have medicinal properties. Cherry leaves contain flavonoid compounds, alkaloids, tannins, saponins, and steroids/triterpenoids. This study aims to determine the antibacterial activity of cherry leaf extract (Muntingiacalabura L) against Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus. Dau cherry extract was prepared using the maceration method using 96% ethanol. The antibacterial activity was tested using the disc diffusion method. The results of the examination of the characteristics of the simplicia powder of cherry leaves obtained water content of 6.7%, water soluble extract content of 23.84%, marine ethanol content of 13.40%, total ash content of 1.61%, and acid insoluble ash content of 0.38%. Simplicia and cherry leaf extract contain flavonoids, alkaloids, tannins, sapomime, steroids/triterpenoids. Antibacterial activity test showed that cherry leaf extract (Muntingiacalabura L) inhibited the growth of Staphylococcus aureus at concentrations of 10% (13.7 mm), 20% (14.1 mm), 30% (15.0 mm), 40% (16, 0 mm), 50% (17.6 mm). Methicillin-Resistant Staphylococcus aureus bacteria at concentrations of extract 10% (13.5 mm), 20% (14.0 mm), 30% (14.8 mm), 40% (15.8 mm), 50% (17, 0mm). Cherry leaf extract has antibacterial activity against Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus bacteria.
PENETAPAN KADAR ETANOL PADA TAPE SINGKONG (Manihot utilissima) DENGAN PENAMBAHAN SARI BUAH NANAS (Ananas comosus) Siti Nurbaya; Siti Maimunah; Zuhairiah Zuhairiah
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2758

Abstract

Cassava tape is a tape made from fermented cassava. The fermentation process is one way to turn food into the product we want by using microbes. This study aims to determine the effect of adding pineapple juice (Ananas comosus) to the ethanol content of cassava tape (Manihot utilissima). Experimental research method with distillate examination, in the distillation process. The sample used was cassava tape (Manihot utilissima) with variations in the volume of addition of pineapple juice (Ananas comosus) 50 ml, 60 ml, and 70 ml, with a fermentation time of 3 days. The sampling technique used is purposive sampling. The results of weighing the ethanol content with a pycnometer will be matched based on its specific gravity. The results of the study of ethanol levels in cassava tape (Manihot utilissima) with a volume variation of the addition of 50 ml of pineapple juice (Ananas comosus) obtained 2.71% results, with the addition of 60 ml the results were 3.19%, with the addition of 70 ml the results were 3.88%. Meanwhile, the ethanol content of cassava tape (Manihot utilissima) without pineapple juice (Ananas comosus) was found to be 1.88%. The conclusion of this study was that the ethanol content of cassava tape (Manihot utilissima) with the addition of pineapple juice (Ananas comosus) increased.
PENETAPAN ANGKA KAPANG KHAMIR (AKK) PADA REMPAH-REMPAH YANG DIJUAL DI PASAR SRI GUNTING MEDAN Siti Maimunah; Karnerius Harefa; Yosy Cinthya Eriwaty Silalahi; Kesaktian Manurung
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i1.2761

Abstract

Spices containing fungal contamination exceed the stipulated limit of 1x104 colonies/g which will affect the stability of the preparation and aflatoxins that are harmful to health such as liver cancer. This study aims to determine the value of the yeast mold number (AKK) in spices at the Sri Gunting market, Medan. The population in this study were spices in the form of wet powder, namely turmeric (Curcuma longa Linn.), ginger (Zingiber officinale Rosc.), and temulawak (Curcuma xanthorhiza Roxb.), and 250 grams of each ingredient was taken from four spice traders. with location criteria such as on the edge of a highway, near a ditch/gully, inside a kiosk, and near a meat seller as a sample. Subjects of research and observations are presented in the form of tables and figures which are then analyzed descriptively. The results of the study found that the AKK of spices sold at the Sri Gunting market in Medan was equal to trader A (turmeric 16.1x10^4, Ginger 7.9x10^4, Temulawak 11.1x10^4cfu/g), trader B (turmeric > 150, Ginger 11.5x10^4Temulawak 18x10^4cfu/g), merchant C (turmeric 12.2x10^4, Ginger 6.1x10^4, Temulawak 4.5x10^4cfu/g), and merchant D (turmeric >150, Ginger 10.9x10^4, Temulawak >150cfu/g) which means that the AKK contained from spices sold at the Sri Gunting market in Medan does not meet the requirements according to the Food and Drug Supervisory Agency (BPOM).
UJI PENINGKATAN KADAR ASAM AMINO PADA TAPE KETAN HITAM DENGAN PENAMBAHAN SARI BUAH NANAS DENGAN METODE SPEKTROFOTOMETRI SINAR TAMPAK Supartiningsih Supartiningsih; Siti Maimunah; Yosy Cinthya Eriwaty Silalahi
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i1.2764

Abstract

Amino acid levels in sticky rice tape are still relatively low, while amino acids themselves are food substances for body growth. Pineapple contains the enzyme bromelain. This enzyme is one of the protease enzymes that can hydrolyze protein, therefore it can increase amino acid levels. This study aims to determine the increase in amino acid levels in black sticky rice tape with the addition of pineapple juice and to determine the effect of adding pineapple juice to amino acid levels in black sticky rice tape. In the process of making black sticky rice tape, 25 ml 50 ml of pineapple juice was added per 500 grams each, while one treatment did not add pineapple juice as a control. Black glutinous rice that has been fermented for 2-3 days was tested for increased levels of amino acids by using visible light spectrophotometry. The sample of black glutinous tape without the addition of pineapple juice obtained an average content of 4.73%, on the sample of black glutinous tape with the addition of 25 ml of pineapple juice the average content obtained was 6.50%, and the sample of black sticky rice tape with the addition of 50 ml pineapple juice the average level obtained was 7.76% and gave the effect of increasing amino acid levels on black sticky rice tape.
ANALISIS MIKROBIOLOGI Escherichia coli JAJANAN MINUMAN DI SEKITAR JALAN KAPTEN MUSLIM KOTA MEDAN Siti Maimunah; Artha Yuliana Sianipar; Cut Masyithah Thaib
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i1.2767

Abstract

Escherichia coli is a gram-negative rod bacteria, not encapsulated and is a normal flora in the digestive tract of animals and humans that easily pollutes water. Escherichia coli can turn into an opportunist pathogen if it lives outside the intestine, for example in urinary tract infections, wound infections and mastitis. Drinks contaminated with microorganisms can cause health problems in the form of disturbances in the digestive tract with symptoms of nausea, heartburn, vomiting and diarrhea. The purpose of this study was to determine the presence of Escherichia coli bacterial contamination in snacks sold around the Kapten Muslimstreet. This descriptive study used 4 samples of iced drinks, namely young coconut ice, sugar cane ice, mixed ice and dawet ice. The sample testing technique uses the Most Probable Number (MPN) method. The media used in this study were lactose Broth, Brilliant Green Lactose Bile Broth, Eosin Methylene Blue Agar. This research was conducted at the Pharmacy Microbiology Laboratory, Sari Mutiara University, Indonesia. After the research, the results showed that 1 of 4 samples of snacks found on Jalan Captain Muslim was detected with Escherichia coli bacteria ranging from 2,800 cells/100 ml so that it was included in the poor criteria, in the category These snacks are not suitable for consumption and do not meet the criteria set out in the Indonesian Ministry of Health No.492/Menkes/Per/IV/2010 (Colifrom and Escherichia coli 0/100 ml).
PENGARUH VARIASI WAKTU FERMENTASI TERHADAP KADAR ETANOL HASIL FERMENTASI SINGKONG KUNING (Manihotutillissima Pohl) Siti Maimunah; Zuhairiah Zuhairiah; Artha Yuliana Sianipar
Jurnal Farmanesia Vol 7 No 2 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i2.2775

Abstract

Cassava is an agricultural commodity that is widely grown in Indonesia and is an important source of carbohydrates after rice with a content of 34.7%. Yellow cassava is usually served in the form of tape through a fermentation process. This study aims to determine the effect of variations in fermentation time on ethanol content resulting from yellow cassava fermentation. This study used an experimental method with the distillation method using yellow cassava samples which were fermented for 72 hours, 96 hours, and 120 hours. The results of this study indicate that there is an effect of time variation on the ethanol content of fermented yellow cassava with a value of 0.93% (72 hours), 1.00% (96 hours), 1.27% (120 hours) which has a very significant effect (p < 0.01 >). The yield of this fermentation can be determined using the alcohol BJ table.
UJI AKTIVITAS ANTIBAKTERI MADU HUTAN TERHADAP BAKTERI Bacillus cereus Siti Maimunah; Supartiningsih Supartiningsih; Jon Kenedy Marpaung; Yosy Cinthya Eriwaty Silalahi; Icha Wahyuni Turnip
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i1.2780

Abstract

Honey is a thick sweet liquid which comes from bees which can cure many diseases and is antibacterial. Antibacterial potential of honey caused by the content of active compounds, low moisture content, high osmolarity, hydrogen peroxide content, and low pH.The aim of this study was to determine the antibacterial activity of forest honey on Doloksaribu, Simalungun district on the growth of Bacillus cereus bacteria.Experiment research method includes the analysis quality of honey, includes checking moisture content, ash content, pH tested, acidity, viscosity, spesific gravityphytochemical screening, and antibacterial activity test ith disk diffusion method use blank disk with each concentration 25%, 35%, 45%, 55%, and 65%, positive control using erythromycin and negative control sterile distilled water. Organoleptic test conducted on forest honey gave results that honey reach the requirements for good quality. The result of moisture and ash content test and pH test reach of SNI 3545: 2013 about honey. Antibacterial activity test of forest honey with concentration 25%, 35%, 45%, 55%, and 65% against Bacillus cereus showed that there was an inhibitory around the blank disc, namely 10,16 mm, 13 mm, 15,6 mm, 21,6 mm, and 22,6 mm. The greatest inhibition of forest honey occurred at the highest concentration that is 65% (22,6 mm).
PENETAPAN KADAR KAFEIN DARI BUBUK KOPI YANG DIPEROLEH DARI KOTA SIDIKALANG SECARA SPEKTROFOTOMETRI UV Siti Maimunah; Supartiningsih Supartiningsih; Devina Chandra
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i1.2782

Abstract

Coffee has many health benefits, such as stimulating the central nervous system, with the effect of relieving fatigue, drowsiness, and also in creasing concentration power. How ever, excessiveuse of caffeine can cause heart palpitations, stomachdi sorders, and shaking hands. Caffeine levels in coffee circulating in the market vary, dueto a mixtureofotheringredients. For this reason, the National Standardization Agency (BSN) has set a standard for caffeine content in coffeepowder, whichis 0.455%-2% w/w (SNI 01-3542-2004), so that if there is coffee containing high levels of caffeine, it needs to be decaffeinated. tosuppresstheactivityofcaffeine in thebody. The purpose of this study was to determine the caffeine content of Arabica coffee powder and Robusta coffee. The samples determined were 2 types of arabica coffee powder, namely those obtained from high stems and low stems, and 1 robusta coffee powder. Sampling was carried out purposively, and as says were determined using ultraviolet spectrophotometry after extraction using chloroform. The results showed that the caffeine content of high-stem Arabica coffee powder was 1.675% (16.75mg/g), low-stemmed 0.546% (5.462 mg/g), and 0.818% (8.18mg/g) of Robusta coffeegrounds. In conclusion, the caffeine levels of the three samples determinedmet the requirements of the Indonesian National Standard.
Co-Authors Adiansyah Adiansyah Ahmad Hafizullah Ritonga Arifin Hulu Artha Yuliana Cahaya Amalia Sitorus Cut Masyithah Cut Masyithah Thaib Devina Chandra Dina Riani Purba Eka Margaret Sinaga Eka Margaretha Sinaga Elly Nurita Sitorus Elly Sitorus Erly Sitompul Fitri Yulia Sari Icha Wahyuni Turnip Ika Kristina Jon Kenedy Marpaung Karnerius Harefa Karnerius Harefa Kesaktian Manurung Kristini Siboro Maringan Silitonga Nikmat Jayadi Nurul Hazlinda Pandapotan Nasution Rifka Gloria Risda Hernidawati Nainggolan Sarah Lestari Setiawati Gea Sianipar, Artha Yuliana Siti Nurbaya Supartiningsih Supartiningsih Supartiningsih Supartiningsih Surfin Putri Yanti Yettrie Simarmata Yosy Cinthya Eriwaty Silalahi Yosy Cinthya Eriwaty Silalahi Zuhairiah Zuhairiah