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All Journal Jurnal Sain Veteriner Indonesian Journal of Tropical and Infectious Disease Jurnal Medik Veteriner ARSHI Veterinary Letters Journal of Parasite Science Ovozoa: Journal of Animal Reproduction Sibatik Journal : Jurnal Ilmiah Bidang Sosial, Ekonomi, Budaya, Teknologi, Dan Pendidikan
Ira Sari Yudaniayanti
Departemen Klinik Veteriner, Fakultas Kedokteran Hewan, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Arts Biochemistry, Genetics & Molecular Biology Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary

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Journal : Ovozoa: Journal of Animal Reproduction

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Moringa oleifera leaf extract restored the diameter and epithelium thickness of the seminiferous tubules of rat (Rattus norvegicus) injected with gentamicin Meidy Mardatillah; Wurlina Wurlina; Ira Sari Yudaniayanti; Hardany Primarizky; Hani Plumeriastuti; Iwan Sahrial Hamid
Ovozoa : Journal of Animal Reproduction Vol. 11 No. 1 (2022): Ovozoa : Journal of Animal Reproduction
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ovz.v11i1.2022.15-21

Abstract

This research aims to determine the effect of Moringa oleifera leaf extract (MLE) on the diameter and epithelium thickness of the seminiferous tubules of rats induced with gentamicin. This study used 25 male rats (Rattus norvegicus) aged 8-12 weeks with 150-200 grams body weight. Negative control group (C-) was injected with aquadest and given 0.5% Na-CMC orally, positive control group (C+) was induced with gentamicin injection of 5 mg/kg BW/day and given 0.5% Na-CMC orally, while groups T1, T2, and T3 were induced with gentamicin at the same dose and treated orally with MLE of 200, 316, 500 mg/kg BW/day. Analysis of variance showed significant differences and further analysis using Duncan Multiple Range Test showed difference in each group. The results showed that treatment with MLE of 500 mg/kg BW/day improved the diameter and epithelium thickness of the seminiferous tubules of rats injected with gentamicin. It could be concluded that MLE restored the diameter and epithelium thickness of the seminiferous tubules of rats induced with gentamicin.
Co-Authors Abdullah Hasib Aditya Yudhana Aisyah Novasari Amalia Rosydinasari Rosydinasari Amung Logam Saputro Amung Logam Saputro Amung Logam Saputro Angela Swasti Ivanalee Bambang Sektiari Lukiswanto Boedi Setiawan Dewi Mariyam Dinda Dwi Prastika Endah Paraswati Hani Plumeriastuti Imam Mustofa Inggarsetya Syah Audini Iwan Sahrial Hamid Iwan Sahrial Hamid Koesnoto Supranianondo Kuncoro Puguh Santoso Kusnoto Kusnoto Lucia Tri Suwanti, Lucia Tri M. Zainal Arifin Maslichah Mafruchati Maya Nurwartanti Yunita Meidy Mardatillah Moh Anam Al Arif Mufasirin Muhammad Huda Ramadhan Ibrahim Nunuk Dyah Retno Lastuti Nurmitasari Rahmadhani Nurul Tri Wahyudi Nusdianto Triakoso Nusdianto Triaoso Prima Ayu Wibawati Primarizky, Hardany Revita Vandarischa Prameswari Rimala Aisyah Rizka Wulan Cahya Rizki Putrianirma Salsabilla Abani Samsi Yordan Sarmanu Sarmanu Setiawan Koesdarto Setiawati Sigit Siti Nur Rohmah Sofyan, Miyayu Soneta Sri Hidanah Sri Mumpuni Sri Mumpuni Sosiawati Sunarso, Agus Tegar Farizky Rusnalendra Widya Paramita Winda Ayu Puteri Sumartono Wurlina w