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Journal : NurseLine Journal

The Difference of Eosinophil Amount in Tuberculosis Patients with and without Soil-Transmitted Helminths Co-infection in Panti District, Jember Yunita Armiyanti; Nisrina Salsabila Firmansyah; Angga Mardro Raharjo; Muhammad Ali Shodikin; Enny Suswati; Dini Agustina
NurseLine Journal Vol 5 No 1 (2020): May 2020
Publisher : Faculty of Nursing, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/nlj.v5i1.16729

Abstract

Tuberculosis is one of the world's health problems even in Indonesia. The immune response that needed to deal with TB can be influenced by other infections, such as helminth infection. The helminth infections induce Th2 immune responses and eosinophilia to eliminate these pathogen. Meanwhile, the Th2 response and eosinophilia can also suppress the Th1 immune response which is very important to eliminate the bacterium M. tuberculosis and make a negative impact on the success of TB therapy. Thus, the eosinophil profile can describe the immune response in TB patients with helminth co-infection. This study aims to determine the prevalence of helminthiasis in TB patients and determine the differences in eosinophil amount in tuberculosis patients with and without helminth co-infection. This study was an observational analytic study with a cross-sectional design conducted at Puskesmas Panti in August 2019-January 2020 using fecal and blood samples from 24 research subjects. Helminth co-infection status was obtained from fecal examination with sedimentation and flotation methods while the number of eosinophils was obtained from leukocyte counts. Data analysis used the Mann Whitney U test to determine differences in the number of eosinophils in the two groups. The results showed there was no difference in the number of eosinophils in TB patients with helminth co-infection and without helminth co-infection (p> 0.05). There is no typical picture of the number of eosinophils in both groups so that eosinophils cannot describe the immune response that arose in TB patients with helminth co-infections in Panti district, Jember.
Co-Authors Abu Khoiri Aditya Oktavianto Ahmad Hasbi Al-Muzaky Ahmad Hasbi Al-Muzaky Alvien Zahrotun Nadhiva Angga M Raharjo Angga Mardro Raharjo Anisa Rizca Putri APRI KUNTARININGSIH Arifah Nur Hasanah Ariska Nur Aida asihanti rosita ferdiana Azham Purwandhono Bagus Hermansyah Bagus Hermansyah Bagus Hermansyah Bagus Satrio Pambudi Bagus Satrio Pambudi, Bagus Satrio Bima Setia Sandya Nugraha Cholis Abrori, Cholis Desie D. Wisudanti Desie Dwi Wisudanti, Desie Dwi Devi Chintya Kumalasari Dian H. Purnamasari Diana C Diana C Mufida Diana C. Mufida Diana Chusna Mufida Dini Agustina Dwita Aryadina Dwita Aryadina Rachmawati Elly N Sakinah Elly Nurus Sakinah, Elly Nurus Elvia Rahmi Marga Putri Erfan Efendi Habib Mustofa Hanifah S Haq I Ketut Sudiana Ika Rahmawati Sutejo Indra Samudra Rahmat Indra Samudra Rahmat Jauhar Firdaus Joko Mariyono Kirana Nadyatara Kristianningrum Dian Sofiana Lailatis Shofia Laksmi Indreswari Laylatul Fitriyah Mukarromah M. Ali Shodikin Misnawi Misnawi Misnawi Misnawi Mufida Mufida Muhammad A. Shodikin Muhammad Alif Taryafi Nexia Nevarachell Onny Amirsyah Nindya Shinta Rumastika Nisrina Salsabila Firmansyah Nita Alfianti NUR K. AGUSTIN Nurhayati Nurhayati Prayoga Adinawer Sirait Probosutiksna, Nuno Febrian Probosutiksna, Nuno Febrian Putu Ayu Laksmi Lestari Regina Finka Risty Pradana Linggan Wangi Salsabila, Yuna Annisa Saskia Mediawati septa surya wahyudi, septa surya Shofia, Lailatis Siti Ananda Hardita Syahputri Supangat Supangat Supangat Supangat Suryono Suryono Ulfa Elfiah Wahyuning Ati Ashari Wiwien Sugih Utami Wiwin Sugih Utami Yudha Nurdian Yudha Nurdian Yuna Annisa Salsabila Yunita Armiyanti Yunita Armiyanti Yunita Wulansari