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Toksisitas Ekstrak Terpurifikasi Daun Buas-Buas (Premna serratifolia L.) terhadap Mortalitas Larva Nyamuk Culex sp. Ulmiyatul Alifiah Zahroh; Dwi Wahyuni; Mochammad Iqbal
saintifika Vol 24 No 1 (2022)
Publisher : FKIP Universitas Jember

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Abstract

Culex sp. is a vector of filariasis. Vector control mostly uses chemical insecticides which have a negative impact. Buas-buas plants (Premna serratifolia L.) are one of the plants that have the potential as an alternative to the use of chemical insecticides that have been widely used (as botanical insecticides). Buas-buas leaves (Premna serratifolia L.) contain alkaloids, flavonoids, saponins, and tannins. This study aimed to test the toxicity of the purified extract of buas-buas leaf (Lethal concentration 50) on the mortality of Culex sp. larvae with an exposure time of 24 hours. Serial concentrations of purified extract used were 850, 1350, 1850, 2350, and 2850 ppm with four repetitions. Each treatment used 20 Culex sp. late three to early four instars. Toxicity testing of Culex sp. gives an LC50 result of 1799.77 ppm..
TOKSISITAS GRANULA EKSTRAK BUAH JERUK NIPIS (Citrus aurantifolia L.) TERHADAP MORTALITAS BERUDU (Phyrinoidis aspera) Renny Ria Fitriani; Dwi Wahyuni; Kamalia Fikri
saintifika Vol 19 No 2 (2017)
Publisher : FKIP Universitas Jember

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Abstract

Granules extract of clime fruit (Citrus aurantifolia L.) is a biolarvasida in eradicating Aedes aegypti mosquito larvae L. Granules extract of lime fruit (Citrus aurantifolia L.) can kill mosquito larvae because its content of limonoida, tannin, flavonoid, and volatile oil. The compound is lethal to the larvae which will enter the body of the larvae of the Aedes aegypti L. mosquito which disrupts the systems in its body. The purpose of this article is to determine the safety of lime fruit (Citrus aurantifolia L.) extract granules on non-target animals, namely tadpoles. Tadpole has the same habitat with mosquito larvae so it is done safety test of citrus fruit extract granule (Citrus aurantifolia L.). Tadpole is a larval phase in Amphibi that continues to experience morphological development in water. The initial phase of tadpoles growth is a phase of adaptation to its habitat. Individuals who can not adapt well will experience a faster death. The research method used is laboratory experimental. The analysis used is ANOVA. The independent variables in this study were the variety of granules extract concentration of citrus fruit (Citrus aurantifolia L.). Tadpole mortality became the dependent variable in this study. Tadpole mortality is characterized by tadpoles collapsing at the time of administration of granules. The results showed that the lime extract granules (Citrus aurantifolia L.) proved safe.
Formulation and Antibacterial Activity of Porang (Amorphophallus muelleri Blume) Extract Gel Against Propionibacterium acne Nurshalati Tahar; Dwi Wahyuni; Rabiatul Adawiyah; Khaerani; Munifah Wahyuddin
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 6 No. 1 (2023)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v6i1.38744

Abstract

Introduction: The increase in bacterial resistance to antibiotics provides an opportunity to obtain antibacterial compounds from natural ingredients. Porang is a plant belonging to the Araceae family that has potential against Propionibacterium acne. Aims: This study aims to determine the effectiveness of the preparation of porang tuber extract gel against Propionibacterium acne. Methods: The porang were extraction by maceration using ethanol. The extract porang were made gel with various concentration and evaluation their stability and antibacterial activity using disc diffusion method. Result: The hedonic test showed no significant differenece each of formula and stable during storage in two weeks. On the other hand, only formula F2 and F3 can inhibit of Propionibacterium acnee. Conclusion: The porang extract can made of gel and good stability. The formula F2 and F3 have antibacterial activity.