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Hubungan Prostate Volume dan Intravesical Prostatic Protrusion terhadap International Prostate Symptom Score pada Pasien Benign Prostate Hyperplasia (Relationship between Prostate Volume and Intravesical Prostatic Protrusion and International Prostate Rahma Illa Putri Utami; Septa Surya Wahyudi; Yuli Hermansyah
Pustaka Kesehatan Vol 6 No 1 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i1.6792

Abstract

Diagnosis of benign prostate hyperplasia (BPH) can be established through transabdominal ultrasonography (TAUS), a noninvasive supportive examination which measure prostate volume (PV), and intravesical prostatic protrusion (IPP). The severity of obstructive symptoms experienced by the patient was assessed by international prostate symptom score (IPSS) questionnaire. This study aimed to analyse the relationship between both PV and IPP and IPSS in BPH patients. This was an observational analytic study with cross sectional design conducted at Department of Urology Surgery Bina Sehat Hospital Jember, Paru Hospital Jember and Bhayangkara Hospital Bondowoso during October-November 2016 in 30 respondents. The average of PV was 52.01±25.18 mL, IPP was 12.67±6.69 mm and IPSS score was 25.60±9.20. The results of Spearman correlation between the PV and Voiding-IPSS, Storage-IPSS, or total score IPSS and IPP and Voiding IPSS showed no significant correlation (p =0.319; p=0.067; p=0.085; p=0.183). Spearman correlation between the IPP and Storage-IPSS or total score IPSS resulted p value equal to 0.012 and r=0.451 and p=0.027 and r=0.404, which showed a significant correlation with moderate correlation strength. Statistically, IPP correlated to IPSS score better than PV. Keywords: BPH, international prostate symptom score, transabdominal ultrasonography
Uji in vitro Aktivitas Antibakteri Minyak Atsiri Batang Sereh (Cymbopogon citratus) terhadap Shigella dysenteriae Yunita Wulansari; Enny Suswati; Septa Surya Wahyudi
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7665

Abstract

Shigella dysenteriae is bacteria that caused diarrhea with high morbidity and mortality. Resistance and toxicity has reported in some antibiotics therapy towards S. dysentriae. Therefore, alternative therapy based on herbal plants is needed. Chymbopogon citratus oil can be used as an antibacterial to Escherichia coli, Klebsiella pneumoniae, Streptococcus mutans, all strains Staphlylococcus sp, Bacillus cereus and Bacillus subtilis. This study aimed to investigate antibacterial activity of C. citratus oils on the growth of S. dysentriae and its minimum inhibitory concentration (MIC). This type of research was a quasi experimental. Antibacterial activity test performed by diffusion method. Subjects in this study were S. dysentriae. C. citratus oil concentration used were 15 μl/ml, 20 μl/ml, 25 μl/ml, 30 μl/ml, 35 μl/ml and 40 μl/ml. Positive control group was given ciprofloxacin 5 μl/ml and a negative control group was given tween-80. Inhibition zone was observed at a concentration of 25 µl/ml (P3). The MIC of C. citratus oils againts S. dysentriae was at a concentration of 25 µl/ml. Kruskal Wallis analysis showed that p=0.000 and α=0.05, it was revealed that there were differences between antibacterial activity amoung tested group with different concentration. Keywords: Shigella dysenteriae, Chymbopogon citratus oil, antibacterial
Pengaruh Vitamin C terhadap Fragilitas Osmotik Eritrosit pada Mahasiswa Kedokteran Universitas Jember yang Mengalami Stres Psikologis Zulfahmi Muslim; Aris Prasetyo; Septa Surya Wahyudi
Pustaka Kesehatan Vol 7 No 1 (2019): Volume 7 No. 1, 2019
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v7i1.17585

Abstract

Medical students are constantly getting stress that could lead to oxidative stress where the level of free radicals is higher than the level of antioxidants in the body. Free radicals can bind to erythrocyte membranes and alter membrane structure that lead to the integrity of the erythrocyte membrane resulting in decreased erythrocyte ability in preventing hemolysis. Vitamin C is an antioxidant that could prevent free radicals bond to erythrocyte membrane. Vitamin C works by donating electrons to free radicals and prevent binding to erythrocyte membranes. The purposed of this study was to determine the effect of vitamin C consumption on osmotic fragility of erythrocytes in medical students with psychological stress. This research was clinical trial research with quasi experimental with pretest-posttest control group design. Researchers used Depression Anxiety Stress Scale (DASS) questionnaire to measure the stress level. Data analysis using T test obtained mean of percentage of hemolysis between pretest and posttest was p= 0,02. It can be concluded that there is significant difference on osmotic fragility due to Vitamin C consumption in medical Student of Jember University with psychological stress.
Pengaruh Pemberian Gel Doksisiklin terhadap Jumlah Makrofag pada Proses Penyembuhan Dermatitis Paederus akibat Racun Tomcat (Paederus sp.) pada Mencit (The Effect of Doxycycline Gel Application toward the Number of Macrophage in Dermatitis Paederus He Bagus Indra Kusuma; Al Munawir; Septa Surya Wahyudi
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Paederus dermatitis is an acute skin irritation caused by skin contact with toxins in the rove beetle (Paederus sp). Pederin poison was previously thought derived from the rove beetle's body. Based on other studies, poison pederin obtain from the symbiotic rove beetles and Pseudomonas aeruginosa which is able to secrete the matrix metalloprotease (MMP). Doxycycline is an antibiotic act as an inhibitor of MMP. This study aimed to verify the effect of Doxycycline gel to the number of macrophages in healing process Paederus dermatitis due to poison of rove beetle (Paederus sp.). The study design was a quasy experimental design using 40 mice (Mus musculus), were divided into 4 groups. Normal control group, negative control group, P1 group was given doxycycline 1%, and P2 group was given doxycycline 5%. Experimental animals were terminated on day 1, 3, 5, 7, and 15. The result of One Way Annova test on the number of macrophages on day 1, 3 and 5 showed a significance of 0.00 (p<0.05). This study showed that there was a significant difference in the effect of doxycycline gel to the number of macrophages in healing process of Paederus dermatitis. Keywords: dermatitis paederus, doxycycline gel, macrophages
Hubungan karakteristik pesenam terhadap keluhan nyeri lutut Ika Rahmawati Sutejo; I Nyoman Insan Parisudha; Septa Surya Wahyudi
MEDIKORA Vol 21, No 1 (2022): April
Publisher : Faculty of Sports Sciences, Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/medikora.v21i1.45004

Abstract

Penelitian ini bertujuan untuk membuktikan hubungan karakteristik pesenam terhadap keluhan nyeri lutut. Penelitian ini merupakan penelitian analitik observasional dengan rancangan cross sectional. Populasi dalam penelitian ini adalah 60 orang, denagn rincian 30 untuk kelompok pesenam aerobik dan 30 untuk pesenam zumba. Kriteria inklusi yang dipakai adalah jenis kelamin wanita, frekuensi senam minimal satu kali dalam seminggu secara rutin selama minimal selama enam bulan, waktu senam dalam sekali latihan antara tiga puluh hingga enam puluh menit, dan telah mengisi informed consent sebelum pengisian kuesioner. Pengambilan data dilakukan dengan cara memberikan kuesioner mengunakan google form. Karakteristik pesenam yang dibandingkan pada penelitian ini antara lain frekuensi, usia, jenis senam, indeks massa tubuh (IMT), dan lama mengikuti senam dalam satu tahun. Skala nyeri lutut diukur menggunakan Number Rating Scale (NRS). Hasil analisis multivariat dengan uji logistik berganda menunjukkan hanya satu variabel yang berpengaruh signifikan, yaitu frekuensi senam dalam seminggu (p=0,044). Frekuensi senam berpengaruh terhadap nyeri lutut pesenam dengan Odds ratio (OR) sebesar 5,218. Karakteristik frekuensi senam berhubungan terhadap keluhan nyeri lutut (p=0,044) dengan nilai odds ratio 5,218. Usia tidak menunjukkan korelasi dengan keluhan nyeri lutut. Tidak ada hubungan IMT dengan nyeri lutut pesenam (p=0,178). Tidak ada hubungan jenis senam, baik zumba maupun aerobik dengan keluhan nyeri lutut. Lama mengikuti senam (dalam tahun) tidak berhubungan dengan keluhan nyeri lutut. Penelitian ini menyimpulkan frekuensi senam merupakan faktor risiko yang memengaruhi keluhan nyeri lutut pesenamThe correlation of gymnast characteristics with knee pain incidenceAbstracthis study aims to prove the relationship between the characteristics of the gymnast and complaints of knee pain. This research is an observational analytic study with a cross-sectional design. The population in this study was 60 people, with details of 30 for the aerobic gymnast group and 30 for the zumba gymnast. The inclusion criteria used were female gender, frequency of exercise at least once a week regularly for a minimum of six months, exercise time in one exercise between thirty to sixty minutes, and having filled out informed consent before filling out the questionnaire. Data collection was done by giving a questionnaire using a google form. The characteristics of the gymnasts compared in this study included frequency, age, type of exercise, body mass index (BMI), and length of time following the exercise in one year. The knee pain scale was measured using the Number Rating Scale (NRS). The results of multivariate analysis with multiple logistic tests showed that only one variable had a significant effect, namely the frequency of exercise in a week (p=0.044). The frequency of exercise has an effect on gymnast knee pain with an Odds ratio (OR) of 5.218. The characteristics of the frequency of exercise were associated with complaints of knee pain (p=0.044) with an odds ratio of 5.218. Age did not show a correlation with complaints of knee pain. There was no relationship between BMI and gymnast knee pain (p=0.178). There is no relationship between types of exercise, both Zumba and aerobics, with complaints of knee pain. Duration of exercise (in years) was not associated with complaints of knee pain. This study concludes that the frequency of exercise is a risk factor that affects the gymnast's knee pain complaints.
The Sensitivity Pattern of Bacteria Against Antibiotics in Urinary Tract Infection Patients at RSD DR. Soebandi Jember Ryan Ravi Is Syahputra; Dini Agustina; Septa Surya Wahyudi
Journal of Agromedicine and Medical Sciences Vol 4 No 3 (2018)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v4i3.6786

Abstract

Urinary tract infection (UTI) was infection by microorganisms in the urinary tract. Treatment of UTI required supportive therapy and adequate antibiotics. Antibiotic resistance was the solution in the treatment of UTI, so it is important to assess the factors of bacterial resistance and strategies to control the incidence of resistance by choosing antibiotics in accordance with the pattern of sensitivity of germs obtained. This study aimed to determine the pattern of bacterial susceptibility to antibiotics in patients with UTI in RSD dr. Soebandi Jember. This research used descriptive research design by taking secondary data that was medical record data of urine culture examination and sensitivity test to antibiotics in UTI patients who have been diagnosed in inpatient and outpatient room RSD dr. Soebandi Jember between the period January 1, 2014 until November 30, 2017. The results of this study obtained 57 samples of urine positive bacteria, which found 18 types of bacteria that caused UTI. Of the 18 types of bacteria, there were 16 Gram negative bacteria and 2 Gram positive bacteria. Five bacteria divided among others E. coli on 24 samples, K. ornithinolytica on 5 samples, K. pneumoniae on 4 samples, B. cepacia on 4 samples, and E. cloacae on 3 samples. The results of bacterial sensitivity to antibiotic pattern showed the highest sensitivity level ie amikacin, fosfomicin, netilmicin, gentamicin, and nitrofurantoin. While the results of patterns of bacterial resistance to antibiotics based on hormonal levels of cephalotin, cephazolin, ampicillin, sulphametoxazole, and trimetoprim. Keywords: Urinary Tract Infection (UTI), Bacterial sensitivity, Antibiotics
The Effect of Alopurinol on Blood Urea Nitrogen and Creatinine Serum Levels in Patients with Chronic Kidney Disease Miftakhul Huda; Pulong Wijang Pralampita; Dini Agustina; Cholis Abrori; Septa Surya Wahyudi
Journal of Agromedicine and Medical Sciences Vol 7 No 1 (2021)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v7i1.10928

Abstract

Chronic kidney disease (CKD) is a structural and function disorder of renal for > 3 months with implications for individual health. CKD has become a health problem throughout the world and its implementation provides a considerable economic burden on the health system. The decreasing value of GFR (glomerular filtration rate) in CKD can cause uric acid retention so that serum uric acid levels increase (hyperuricemia). Hyperuricemia can occur due to an increase in urinary metabolism (overproduction), a decrease in uric acid expenditure (underexcretion), or a combination of both. The group of antihyperuricemic drugs that have good effectiveness and long-term safety is xanthine oxidase inhibitors. The commonly used xanthine oxidase inhibitor drug is allopurinol. The purpose of this study was to determine whether there was an effect of allopurinol on kidney function in CKD patients. The results of this study are expected to provide input in the treatment of hyperuricemia in CKD patients and reduce the progression of CKD. This study used a retrospective observational analytic design with a cross-sectional approach. The study population was CKD patients from January 2018 to January 2019 at Bina Sehat Hospital Jember. The sampling technique uses purposive sampling. This study uses secondary data obtained from medical records of CKD patients at Bina Sehat Hospital Jember. Secondary data obtained in the form of identity data and the results of laboratory tests of patients. The medical record data that has been obtained is distributed and analyzed using a paired T-test to compare the mean or mean differences of the two groups in pairs. The bivariate test results for blood urea nitrogen and serum creatinine levels in CKD patients were obtained p <0.001. Based on these results there is a significant relationship between blood urea nitrogen and serum creatinine levels before and after consuming allopurinol. The conclusion was that allopurinol was shown to be able to provide an effect on the kidney function of CKD patients based on blood urea nitrogen and serum creatinine levels. Keywords: Chronic kidney disease, hyperuricemia, allopurinol
The Antibacterial Effect of Ethanol Edamame Seeds (Glycine Max (L) Merril) Extract to E.coli Bacteria Diayu Putri Akhita; Edy Junaidi; Septa Surya Wahyudi
Journal of Agromedicine and Medical Sciences Vol 6 No 3 (2020)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v6i3.11120

Abstract

Abstract Infectious diseases can occur in all parts of the body. One of the causes infection in humans is Eschericiae coli bacteria. Eschericiae coli is a rod-shaped bacteria, a gram negative bacteria, facultative aerobics and classified family member of Enterobacteriaceae from the Gammaproteobacteria class. Along the times, E.coli bacteria have resistent to some antibiotics. So we need a new alternative. There is a antibacterial substance in the isoflavon group contained in edamame. Genistein is a main isoflavon in edamame that have antiinflammation, antibacterial, and antioxidant effects. The purpose of this study was to determine is there any antibacterial effects in ethanol edamame seeds extract to E.coli bacteria. This study used a true experimental research design in vitro with a post test only control group design. The average diameter results of the inhibition zone were analyzed using the Kruskal-Wallis method and obtained p = 0.001 which means there are significant differences in at least two groups. After that, the Mann Whitney post hoc test was conducted and a significant difference was found in the positive and negative control groups for all groups but there was no difference in the treatment group, both groups K1, K2 and K3 for all groups. Keywords : Edamame, Antibacterial, E.coli
Hubungan kualitas tidur dengan tinggi badan pada remaja usia 10-15 tahun Septa surya wahyudi; Ayu munawaroh aziz; Alfina kamelia fakhriyah
Majalah Kedokteran Andalas Vol 44, No 2 (2021): Online July 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v44.i2.p93-103.2021

Abstract

Kualitas tidur yang baik harus dicapai seseorang untuk mendapatkan manfaat dari tidur. Selama periode tidur, tubuh menyekresikan GH dalam darah. Sekresi GH mencapai puncaknya saat tidur nyenyak terutama tengah malam. Kadar GH yang disekresikan saat tidur dapat berpengaruh terhadap pertumbuhan fisik terutama tinggi badan pada masa pertumbuhan.Penelitian ini merupakan observasional analitik, menggunakan pendekatan cross sectional. Bertujuan untuk mengetahui hubungan kualitas tidur dengan tinggi badan pada remaja usia 10-15 tahun. Teknik pengambilan sampel menggunakan teknik proportional stratified random sampling dengan menggunakan kriteria inklusi dan eksklusi. Teknik pengambilan data dilakukan dengan cara wawancara, pemeriksaan tinggi badan berat badan. Analisis data dilakukan menggunakan uji Chi Square.Penelitian menunjukkan sampel yang mempunyai kualitas tidur baik yakni 26 sampel (86,7%), kualitas tidur buruk sebanyak 4 sampel (13,3%). Sebanyak 16 sampel (53,3%) mempunyai tinggi badan sesuai nilai normal menurut usia dalam pedoman WHO, Kemenkes RI, dan CDC pada tahun 2001, 14 sampel (46,7%) lainnya tidak sesuai pedoman tersebut. Hasil uji Chi Square menunjukkan hubungan yang signifikan antara kualitas tidur dengan tinggi badan (p=0,022). Hal ini menunjukkan bahwa terdapat hubungan antara kualitas tidur dengan tinggi badan pada remaja usia 10-15 tahun. Semakin baik kualitas tidur, maka tinggi badan anak akan semakin sesuai dengan nilai normal menurut usia.
The Association Between Hypospadias Occurrence With Exposure Of Pesticides In Agroindustry Enviroment Sri Weli Teguh Pujo Sakti; Supangat Supangat; Septa Surya Wahyudi
NurseLine Journal Vol 3 No 2 (2018): November 2018
Publisher : Faculty of Nursing, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/nlj.v3i2.6615

Abstract

Hypospadias is congenital penis abnormalities in children who are commonly encountered. Structure of the urinary tract is found in the central part of the penis. Many factors cause the occurrence of hypospadias, one of which is exposure to pesticides. Indonesian’s people have a livelihood as farmers, hence the case of contaminated pesticides often occur in the agroindustrial environment. The type of this research is analytic observational by a case-control method which conducted in November until December 2017. The criteria in this study were all hypospadias patients and had undergone treatment at Paru Hospital of Jember, Bina Sehat Hospital of Jember, Bhayangkara Hospital of Bondowoso from January 2015 until November 2017 and close community of patient in one agroindustry region. The sample of this research is 40 samples divides into 20 sample case groups and 20 sample control groups. The data obtained were analyzed by Chi-square test and obtained significant result between the employment relationship (p = 0.011) and pesticide exposure with categories pesticide user (p = 0.026), spacing distance with mother position (p = 0.011), pesticide contact time (p = 0.004), pesticide storage area (p = 0.001) to hypospadias occurrence in the agroindustry environment.