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All Journal Journal of Food and Pharmaceutical Science JURNAL GIZI INDONESIA Media Kesehatan Masyarakat Indonesia Media Gizi Mikro Indonesia Journal of the Medical Sciences (Berkala Ilmu Kedokteran) agriTECH Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Paediatrica Indonesiana GIZI INDONESIA Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery) Jurnal Gizi Klinik Indonesia Jurnal Dunia Gizi BKM Public Health and Community Medicine Journal of Food and Pharmaceutical Sciences
Emy Huriyati
Department Of Health Nutrition, Faculty Of Medicine, Public Health, And Nursing, Universitas Gadjah Mada, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Journal : Journal of Food and Pharmaceutical Science

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The Effect of Synbiotic Shake on Blood Glucose and Lipid Profile in Hyperglycemia Wistar Rats Lily Arsanti Lestari; Inas Nur Hafizhah; Happy Nurlita Octavinanda; Latifah Mahdiyati; Refdiana Dewi; Perdana Samekto Tyasnugroho Suyoto; Emy Huriyati; Sunarti
Journal of Food and Pharmaceutical Sciences Vol 8, No 3 (2020): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.1098

Abstract

Several studies found that the probiotic bacterias such as Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 could prevent glycemia and control the blood lipid profiles. Currently, a probiotic product such as yogurt is not preferable by some consumers since the taste is sour. Therefore, this study was conducted to develop milkshakes supplemented by probiotics Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 which are expected to be more acceptable and have a beneficial effect with the addition of prebiotics and soluble fiber glucomannan. This study aims to determine the effect of synbiotic shakes on fasting blood glucose levels and lipid profiles in hyperglycemia Wistar rat models. The study design was a pre-posttest controlled group with 48 male Wistar rats divided into 8 groups, namely the healthy control group (I); hyperglycemia control group (II); group III that received metformin; group IV that received synbiotic shake with La5 + FOS; group V that received synbiotic shake La5 + inulin; group VI that received synbiotic shake Bb12 + FOS; group VII that received synbiotic shake Bb12 + inulin; and group VIII that received synbiotic shake La5 + Bb12 + FOS. The dose of the intervention was 3.6 ml/day with an intervention duration of 28 days. The results showed that the differences in blood glucose levels were not significant (p> 0.05) except for groups IV and VI that experienced a significant increase (p <0.05). The differences in lipid profiles showed insignificant changes in LDL levels except in groups IV and V, a significant increase in HDL levels (p <0.05) in group V and VI, and insignificant change in triglycerides except in group VI. It can be concluded that the administration of synbiotic shakes with a variety of prebiotics Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 for 4 weeks were able to maintain fasting blood glucose levels and lipid profiles in hyperglycemic rats.
Co-Authors A’yun, Rizka Qurrota Abeng, Andi Tenri Abidillah Mursyid Adhila Fayasari Ahmad Hamim Sadewa Ailsa Nur Rahma Apta Widyadhana Akhmad Sujai Almira Nadia Alpha Olivia Hidayati Alpha Olivia Hidayati Andi Tenri Abeng Annisa Leny Saraswati Atika Sulistyan Ave Anugraheni Cati Martiyana Christin Debora Nabuasa Daniel Robert Daniel Robert, Daniel Darwin Nasution Detty Siti Nurdiati Detty Siti Nurdiati, Detty Siti Dewi Marfuah Dian Caturini Sulistyonigrum Djauhar Ismail Djauhar Ismail Djauhar Ismail Djauhar Ismail Dyah Ayu Kusuma Wardani Elisabeth Pampang Eni Harmayani Eni Harmayani Erinda Nurrahma Fajar Sri Tanjung Farida Nailufar Fitri Ardiani Fitri Ardiani Hamam Hadi Hamam Hadi Hamam Hadi Hamam Hadi Happy Nurlita Octavinanda Hardiana Probosiwi Harry Freitag Luglio Muhammad Husnah Husnah Inas Nur Hafizhah Janatin Ari Kurniawat Alwahyulhaq Jati Sasmito Hastuti Kamsiah . Lastiana Safitri Lastiana Safitri, Lastiana Latifah Mahdiyati Lestari, Lily Arsanti Lily Arsanti Lestari Lily Arsanti Lestari Lisma Evareny, Mohammad Hakimi, Retna Siwi Padmawati M Juffrie Madarina Julia Madarina Julia Madarina Julia Madarina Julia Maria Goretti Adiyanti Maria Goretti Adiyanti, Maria Goretti Martalena Br Purba Martalena Br Purba Martalena Br Purba Martalena Br Purba, Martalena Br Mirza Hapsari Sakti Titis Penggalih Mubasysyir Hasanbasri Mubasysyir Hasanbasri Muhammad Jourdan Prasetyatama Mursyid, Abidillah Mustikaningtyas Mustikaningtyas Mustikaningtyas, Mustikaningtyas Mutiara Tirta Prabandari Lintang Kusuma Nailufar, Farida Nasution, Darwin Ni Komang Wiardani Nur Fitri Widya Astuti Okta Haksaica Sulistyo Pampang, Elisabeth Perdana Samekto Tyasnugroho Suyoto Podojoyo Podojoyo Podojoyo, Podojoyo Pratiwi, Zahra Anggita RAHMANIAH RAHMANIAH Ramadhaniah Ramadhaniah Ramadhaniah, Ramadhaniah Ratih Feraritra Danu Atmaja Refdiana Dewi Rina Susilowati Rina Susilowati Rissa Saputri Rizka Qurrota A’yun Ronny Tri Wirasto Saputri, Rissa Siti Wahdah Sri Ahadi Nugraheni Sri Ahadi Nugraheni, Sri Ahadi Sri Rahayoe Sujai, Akhmad Sulistyan, Atika Sulistyo, Okta Haksaica Sunarti, Sunarti Susetyowati, Susetyowati Toto Sudargo Toto Sudargo Usi Lanita Utami, Nurul Putrie Wardani, Dyah Ayu Kusuma Winda Irwanti Winda Irwanti, Winda Wirasto, Ronny Tri Wiryatun Lestariana Wiryatun Lestariana Wiryatun Lestariana, Wiryatun Yusmiati Yusmiati Yusmiati Yusmiati, Yusmiati Zahra Anggita Pratiwi