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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Indonesian Journal of Tropical and Infectious Disease Health Notions Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya ISM (Intisari Sains Medis) : Jurnal Kedokteran
Evy Ervianti
Departement Of Dermatology And Venereology, Faculty Of Medicine Universitas Airlangga/Dr. Soetomo General Academic Hospital, Universitas Airlangga Teaching Hospital, Surabaya
Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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A Retrospective Study: Characteristics and Management of Gonorrhea Indah Purnamasari; Dwi Murtiastutik; Muhammad Yulianto Listiawan; Evy Ervianti; Rahmadewi Rahmadewi; Budiono Budiono; Astindari Astindari; Maylita Sari; Septiana Widyantari; Afif Nurul Hidayati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 1 (2021): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.1.2021.1-7

Abstract

Background: Gonorrhea (GO) is a sexually transmitted infection that remains an important clinical and public health problem worldwide. Its incidence tends to increase both in males and females. Given the scale of the public health impact of GO, the selection of appropriate therapy is essential. Purpose: This study aimed to evaluate the characteristics, management, and recovery of gonorrhea patients. Methods: The research material was obtained from the medical record of gonorrhea patients at the Sexually Transmitted Infections (STI) Outpatient Clinic, Dermatology and Venerelogy Department, Dr. Soetomo General Academic Teaching Hospital, Surabaya, from January 2016 to December 2018. Result: We found 84 new GO patients (0.02%) out of the total new outpatients at the Dermatology and Venereology Department, Dr. Soetomo General Academic Teaching Hospital, Surabaya. Most of them were males (92.9%), 17–25 years age group (52.4%), unmarried (67.9%), and heterosexual (90.5%). The majority of therapy is dual therapy, was combination of doxycycline and cefixime (78%). Only 34 patients (40.5%) attended the follow-up visits, and 94.1% of them recovered, and 5.9% presented with cystitis. Conclusion: The characteristics features of GO varies in each variable. One of important to control GO is provide effective and appropriate treatment and routinely clinical and laboratories were needed control.
The Comparison of Candida spp. Colonization on Psoriasis Vulgaris Patient and Control Amanda Gracia Manuputty; Dwi Murtiastutik; Sawitri Sawitri; Muhammad Yulianto Listiawan; Rahmadewi Rahmadewi; Afif Nurul Hidayati; Pepy Dwi Endraswari; Evy Ervianti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 1 (2021): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.1.2021.40-47

Abstract

Background: Psoriasis is an inflammatory, chronic, and recurring skin disease that affects patient’s quality of life. Environment, drugs, and infections in the form of antigen and toxin such as Candida spp. are assumed responsible for triggering and exacerbating psoriasis. Purpose: To compare the prevalence of skin colonization of Candida spp. on psoriasis vulgaris patient and control. Methods: This study was observational analytic research involving 33 psoriasis vulgaris patients and 33 healthy individuals. They were matched up based on sex, age, and lesion location. Swab of skin lesions on the Koebner area of both groups was cultured on CHROMagar media. Candida spp. was later identified and the colonization was calculated. Result: Candida spp. was found on 51.5% of lesions in psoriasis vulgaris patients and 21.2% in the control group with a significant difference of p < 0.05. The average colony number of Candida spp. in psoriasis vulgaris group was lower than the control group with no significant difference of p > 0.05. The predominant Candida spp. in the psoriasis vulgaris and control groups was Candida krusei, which were 35.5% and 85.6%, respectively. No significant difference between sex, age, period of complaints, age onset, degree of severity (Psoriasis Area and Severity Index), and therapy history, with positive culture of Candida spp. Conclusion: There was no difference in the number of Candida spp. colonization in the psoriasis vulgaris group and the control group. However, the culture positivity of Candida spp. in the psoriasis vulgaris patients was higher than in the control group.
In Vitro Comparison of Antifungal Activity between Epigallocatechin Gallate EGCG) and Nystatin on Candida Sp. Stored Isolates in HIV/AIDS Patients with Oral Candidiasis Yusuf Wibisono; Afif Nurul Hidayati; Sawitri Sawitri; Iskandar Zulkarnain; Evy Ervianti; Rahmadewi Rahmadewi; Esti Hendradi; Pepy Dwi Endraswari; Dwi Murtiastutik
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 2 (2021): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.2.2021.103-109

Abstract

Background: Oral candidiasis is an oral infection caused by Candida albicans. It is one of the most common opportunistic infections found in patients with Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS). Due to growing resistance and side effects to common antifungal drugs in recent years, there have been many studies on naturalsubstances as antifungal agents. In this study, Epigallocatechin gallate (EGCG) were examined for in vitro antifungal activity against Candida strains. Purpose: To compare the in vitro antifungal activity of EGCG and nystatin towards Candida sp. isolate in HIV/AIDS patients with oral candidiasis. Methods: This research was an experimental laboratory study conducted at the Dr. Soetomo General Academic Hospital, Surabaya. Forty isolates of Candida albicans and Candida non-albicans were included. The isolates were tested for antifungal activity using the well diffusion and microdilution method for nystatin 1000 IU and EGCG 1.25%. Result: Diffusion test results showed a greater inhibition zone for nystatin against all analyzed Candida strains with an average diameter for Candida albicans formed by EGCG of 2.15 mm and 7.4 mm for Candida non-albicans. Meanwhile, based on the microdilution test, EGCG was better than nystatin towards all analyzed Candida strains. This study showed EGCG Minimum Fungicidal Concentration (MFC) as high as 50% (p < 0.05). Conclusion: Nystatin antifungal activity was better than EGCG supported by a greater inhibition zone in the well diffusion method. However, the antifungal activity of EGCG was better than nystatin based on microdilution methods.
Efficacy and Side Effects of Fractional Carbon Dioxide Laser for Acne Scars, Keloids, and Striae Albae in the Dermatovenereology Clinic of Tertiary Hospital: A Retrospective Study Riezky Januar Pramitha; Iskandar Zulkarnain; Evy Ervianti; Rahmadewi Rahmadewi; Afif Nurul Hidayati; Budiono Budiono; Diah Mira Indramaya; Trisniartami Setyaningrum; Menul Ayu Umborowati; Muhammad Yulianto Listiawan
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 1 (2021): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.1.2021.19-27

Abstract

Background: Fractional Carbon Dioxide (CO2) LASER has better efficacy compared to conventional LASER in treating scar tissue such as acne scars, keloids, and striae albae. However, a population with darker skin has a higher risk of side effects, especially in post-inflammatory hyperpigmentation. Purpose: To evaluate the efficacy and side effects of fractional CO2 LASER in new patients with acne scars, keloids, and striae albae in the Dermatovenereology outpatient clinic. Methods: Retrospective analysis was done on 42 medical records of patients who met the inclusion criterion, which was those who have undergone fractional CO2 LASER treatments. The efficacy and side effects of the therapy were identified and analyzed using the Statistical Package for Social Sciences (SPSS) version 17 program. Result: A total of 42.9% of patients underwent fractional CO2 LASER treatments for acne scars, while 31% and 26.1% of patients received treatments for keloids and striae albae, respectively. There was a statistically significant decrease in the degree of acne scar (2.72 ± 0.83), keloid height (2.2 ± 0.405), and striae width (0.39 ± 0.02). The statistically significant side effects were hyperpigmentation (59.5%), crustae (26.2%), erythema ≥ for 4 days (19%), and new acne (19%). Conclusion: Fractional CO2 LASER was effective for treating scar tissue (acne scars, keloids, and striae albae) with a higher incidence of side effects in population with darker skin and post-inflammatory hyperpigmentation.
A Retrospective Study: Epidemiology, Onset, and Duration of Erythema Nodosum Leprosum in Surabaya, Indonesia Cindy Fransisca; Iskandar Zulkarnain; Evy Ervianti; Damayanti Damayanti; Maylita Sari; Budiono Budiono; Medhi Denisa Alinda; Bagus Haryo Kusumaputra; Muhammad Yulianto Listiawan
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 1 (2021): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.1.2021.8-12

Abstract

Background: Erythema nodosum leprosum (ENL) has a chronic and recurrent nature which could reduce patient’s quality of life in addition to the onset of ENL that occurs before, during, or after multidrug treatment, further emphasizing the importance of regular control and education.Purpose:This study aimed to evaluate the epidemiology, onset, duration, and recurrence of ENL. Methods:Data from medical records were obtained for a 3-year retrospective study of multibacillary leprosy patients at the Leprosy Division of the Dermatology and Venereology Outpatient Department, Dr. Soetomo General Hospital Surabaya, with a minimum of 2–5 years follow-up period.Result:The prevalence of  ENL continued to increase almost every year especially in 2017 (32% in 2015; 32% in 2016; and 36% in 2017). ENL most often occurs during the first year of multi-drug therapy (MDT) administration followed by after the release from treatment (RFT) with the latest onset occurring 4 years after RFT. The majority of patients experienced chronic and recurrent reactions with the longest reactions lasting up to 4.5 years (55 months). Conclusion:Knowledge about the onset, duration, and recurrences of ENL are essential, and strict supervision for routine control shall be encouraged to increase the patients’ compliance so as to increase their quality of life.
Profile of Tinea Corporis and Tinea Cruris in Dermatovenereology Clinic of Tertiery Hospital: A Retrospective Study Selvia Yuliani Dwi Ratih Sanggarwati; Manik Retno Wahyunitisari; Linda Astari; Evy Ervianti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 1 (2021): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.1.2021.34-39

Abstract

Background: Tinea corporis and cruris are dermatophytes that infect the skin, and they are caused by Trichophyton sp., Microsporum sp., and Epidermophyton sp. Dermatophyte fungal-infect keratin-containing skin classified by the body’s location, such as tinea corporis (skin besides haired area, body, hands, or feet) and tinea cruris (groin & perineal region). Purpose: To evaluate the clinical profiles and treatments of tinea corporis and cruris at Dermatology and Venereology (DV) outpatient clinic Dr. Soetomo General Academic Hospital in 2018. Methods: A retrospective-descriptive study based on medical records of DV outpatient clinic Dr. Soetomo General Academic Hospital, Surabaya. Data collected from August to December 2019. Tinea corporis and cruris profiles evaluation based on age, sex, occupation, precipitating factors, complaints, illness duration, family history, lesion’s location and description, and therapy. Result: A total of 164 patients (35 tinea corporis, 76 tinea cruris, and 53 tinea corporis and cruris), predominantly female, age 46–55 years, came treatment less-than-a-month cases, excessive sweating, itching, tinea corporis lesion’s location on the face and body, tinea cruris in  groin, tinea corporis and cruris on body and groin, erythematous macules, firm borders, active margins, scales, central healing, positive KOH 10–20% examination, miconazole cream therapy 2%, griseofulvin therapy, griseofulvin oral and ketoconazole cream 2% combination therapy. Discussion: Tinea corporis and cruris are common in females as their history and symptoms supported by the characteristics of laboratory examination, the presence of hyphae in potassium hydroxide (KOH) 10–20%. Most patients were prescribed with oral griseofulvin, especially in large lesions cases.
A Case Report of Tinea Capitis in Children: Utility of Trichoscopy Citra Dwi Harningtyas; Evy Ervianti; Linda Astari; Sylvia Anggraeni
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.66-72

Abstract

Background: Tinea capitis (TC) is the most prevalent pediatric superficial dermatophyte infection. Scalp dermoscopy or “trichoscopy” represents a valuable, noninvasive technique for the evaluation of patients with hair loss due to TC. Purpose: To characterize trichoscopic findings in children with clinical findings suggestive of TC. Case:  A 13-year-old boy was presented with a scaled plaque on his scalp that had appeared 1 month earlier. A physical examination revealed a scaly, nonerythematous, rounded lesion in the parietal area of the head. Wood’s lamp yielded a blue fluorescence. Microscopic morphology from fungal culture found the typical spindle-shaped macroconidia of Microsporum canis. Trichoscopy showed mainly comma hair, corkscrew hair, morse code hair, bent hair, and zig zag hair. The patient was started on oral griseofulvin 20 mg/kg/day and antifungal shampoo for 8 weeks. The patient was cured after two months of treatment and trichoscopy returned to normal. Discussion: Fungal culture remains the gold standard in TC diagnosis, but it needs time. Trichoscopy can be an additional tool to help evaluate the diagnosis, aetiology, and follow up of this disorder. The presence of characteristic trichoscopic features (comma hairs, corkscrew hairs, Morse code-like hairs, zigzag hairs, bent hairs, block hairs, and i-hairs) is predictive of TC. The present analysis confirmed that trichoscopy is a useful method in differentiating between Microsporum and Trichophyton TC, which is important from the perspective of a different therapeutic approach. Conclusion: Trichoscopy is not only of value in the diagnosis of TC but also for the etiologic agent and follow-up after treatment in this case.
The Profile of Psoriasis Vulgaris Patients: A Descriptive Study Afif Nurul Hidayati; Made Putri Hendaria; M. Yulianto Listiawan; Budi Utomo; Damayanti Damayanti; Sylvia Anggraeni; Menul Ayu Umborowati; Evy Ervianti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.173-181

Abstract

Background: Psoriasis is a skin disease that occurs due to proliferation and differentiation disturbances of the epidermis. This chronic condition often reduces the human quality of life. There have been studies investigating psoriatic patient profiles and treatments, but few are conducted in Surabaya. Hence, those studies cannot fully represent the population demographic in Surabaya. Purpose: To investigate the prevalence of psoriasis vulgaris and the sociodemographic profile of the patients in Dr Soetomo General Academic Hospital. Methods: This was a Retrospective study psoriasis vulgaris patients in January 2016–December 2018. The data were collected by retrieving Electronic Medical Records (EMR) as secondary data. Result: The psoriasis vulgaris prevalence of outpatients was 0.46% and 4.59% in inpatients. Most study subjects were adults aged 18 and above (98.1%), most of the patients were obese (46.3%), the most common provoking factor was focal tooth infection (33.8%) and stress (28.8%), and none reported family history of psoriasis. Conclusion: Some results are similar to other studies conducted in Surabaya, which were the obesity and Type 2 Diabetes Mellitus (DM) being strong a factor to psoriasis development. However, the result on psoriasis family history was not in line with other studies.
The Demography, Clinical Characteristics, and White Blood Analysis of Leprosy Reactions in Multibacillary Leprosy: A Retrospective Study Natalia Tanojo; Damayanti Damayanti; Budi Utomo; Evy Ervianti; Dwi Murtiastutik; M. Yulianto Listiawan
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.187-193

Abstract

Background: Leprosy is a neglected tropical disease caused by chronic granulomatous infection of Mycobacterium leprae. Indonesia ranks third in new case findings, with 84% of the case being multibacillary (MB) leprosy. MB leprosy cases have a higher risk of leprosy reactions and physical disabilities that decrease quality of life. Purpose: To determine the demographic, clinical characteristics, and white blood analysis of newly diagnosed MB leprosy patients, especially concerning leprosy reactions. Methods: This is a descriptive retrospective study with a cross-sectional design that describe the following data: domicile, gender, age, treatment status, disabilities, body mass index (BMI); bacterial index (BI), morphological index (MI), white blood cell (WBC) and differential counts, and thrombocyte count. Result: This study included 176 adult MB cases, predominantly male aged 20–39 years old with average BMI, lived in Surabaya with negative history of multi-drug therapy, disability, BI, nor MI. The grade 2 disability (G2D) percentage in this study setting than in Indonesia (10.7% vs. 6.43%). The WBCs, especially neutrophil count, was higher in T2R group. Monocyte and lymphocyte counts were relatively similar. There was an increase in thrombocyte count in leprosy reaction groups. Conclusion: MB leprosy in the endemic area, which is more commonly found in productive-aged male, displayed higher G2D than global Indonesia population. Thus denotes the importance of active case findings. The difference in blood analysis characteristics between MB leprosy with and without reactions may serve as the foundation for future study.
Characteristics of Atopic Dermatitis Patients who Underwent Skin Prick Test Wisnu Triadi Nugroho; Evy Ervianti; Iskandar Zulkarnain; Afif Nurul Hidayati; Damayanti Damayanti; Budi Utomo
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.10-14

Abstract

Background: Skin prick test (SPT) is indicated in type I hypersensitivity reactions (rapid type), among which is Atopic Dermatitis (AD). However, the results of SPT for the tested allergens are not always accompanied by history of known allergens in AD patients. Purpose: To identify the characteristics of AD patients who underwent SPT. Methods: This was a descriptive retrospective study to determine the demographics, allergy history, SPT results, and positive and negative clinical relevance in AD patients treated at Allergy Immunology Division of Dermatology and Venerology Outpatient Clinic Dr. Soetomo General Academic Hospital Surabaya-Indonesia from January 2017 to December 2019. Results: A total of 284 AD patients were included. The adult age group (20-59 years) predominated the AD patient’s visit every year with 58 patients (60.42%), 47 patients (46.08%), and 65 patients (75.58%) in 2017, 2018, and 2019, respectively. Only 60 AD patients underwent SPT, where most patients were allergic to dust with 30 patients (50.0%). House dust mite (HDM) allergen had the highest percentage of positive SPT result with 41 patients (63.3%). The greatest clinical relevance was found in cat fur allergen, where all patients (100.0%) had clinical relevance to their SPT result. Conclusion: This study shows that most AD patients were in adult age group and had a history of dust allergy. The highest percentage of positive SPT result was found in HDM allergen and the greatest clinical relevance was found in cat fur allergen.
Co-Authors Addia Salsabila Ade Fernandes Ade Fernandes Afif Nurul Hidayati Afif Nurul Hidayati Alphania Rahniayu Amanda Gracia Manuputty Amira Suryani Rahmatika Anang Endaryanto Andre Yuindartanto Arthur Pohan Kawilarang Astindari Astindari Astindari Astindari Astindari Bagus Bagus Bagus Haryo Kusumaputra Bagus Haryo Kusumaputra Bagus Meurah Suropati Bernadya Yogatri Anjuwita Budi Utomo Budi Utomo Budi Utomo Budi Utomo Budi Utomo Budiono Budiono Chesia Christiani Liuwan Cindy Fransisca Cita Rosita Sigit Prakoeswa Citra Dwi Harningtyas Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Desiana Widityaning Sari Dewi Puspitorini Diah Mira Indramaya Diah Nugrahaeni Diah Nugrahaeni, Diah Dwi Murtiastutik Dwi Murtiastutik Dwi Nurwulan Pravitasari Dyatiara Devy Rahadiyanti Dyatiara Devy Rahadiyanti Eko Budi Koendhori, Eko Budi Ellenita Soebakti Endang Wahyu Fitriani Esthy Yuliana Esti Hendradi Farhat Surya Ningrat Fatma Rosida Hamidah Luthfidyaningrum Hans Lumintang Hans Lumintang, Hans I Gusti Ayu Agung Elis Indira I Gusti Nyoman Darmaputra Indah Purnamasari Indiarsa Arief L Indiarsa Arief L, Indiarsa Arief INDROPO AGUSNI Indropo Agusni Indropo Agusni Irmadita Citrashanty Irmadita Citrashanty Iskandar Zulkarnain Iskandar Zulkarnain Iskandar Zulkarnain Iskandar Zulkarnain Iskandar Zulkarnain Karina Dyahtantri Pratiwi Kurniati Kurniati Linda Astari Lunni Gayatri Lunni Gayatri, Lunni M. Yulianto Listiawan Made Putri Hendaria ManikRetno Wahyunitisari Maria Ulfa Sheilaadji Maria Ulfa Sheilaadji Marsudi Hutomo Maya Wardiana Maylita Sari Maylita Sari Maylita Sari Medhi Denisa Alinda Menul Ayu Umborowati Menul Ayu Umborowati Menul Ayu Umborowati Nadya Kelfinta Hanani Natalia Tanojo Nur Khamidah Nyoman Suryawati Pepy Dwi Endraswari Pepy Dwi Endraswari, Pepy Dwi Putri Intan Primasari Putri Intan Primasari Rahmadewi Rahmadewi Regitta Indira Agusni Retha Retha Riezky Januar Pramitha Sawitri Sawitri Sawitri Sawitri Sawitri Sawitri Sawitri Sawitri Selvia Yuliani Dwi Ratih Sanggarwati Septiana Widyantari Shakti Indraprasta Silvani Geani Sunarso Suyoso Sunarso Suyoso Sunarso Suyoso Sunarso Suyoso, Sunarso Sylvia Anggraeni Tjokorde Istri Nyndia Vaniari Trisniartami Setyaningrum Wisnu Triadi Nugroho Wisnu Triadi Nugroho Yoana Fransiska Wahyuning Christi Yuri Widia, Yuri Yuri Widya Yusuf Wibisono zahruddin ahmad