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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences METAMORFOSA Journal of Biological Sciences Jurnal Ilmu Perairan (Aquatic Science) Jurnal Farmasi Andalas Jurnal Sains dan Teknologi Farmasi Jurnal Riset Kimia Indonesian Journal of Pharmaceutical Science and Technology INDONESIAN JOURNAL OF PHARMACY Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL EDUCATION AND DEVELOPMENT JSFK (Jurnal Sains Farmasi & Klinis) JFIOnline Majalah Kedokteran Andalas Jurnal Farmasi Higea JURNAL PENELITIAN FARMASI & HERBAL Journal of Pharmaceutical and Health Research REACTOR : Journal of Research On Chemistry And Engineering
Akmal Djamaan
Universitas Andalas
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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Kajian Biodegradasi Filem Plastik Campuran Polistiren dengan Poli(3hidroksibutirat-ko-3-hidroksivalerat) dalam Tanah Secara In-vitro Permatadewi, Asiska; Zaini, Erizal; Rustini, Rustini; Djamaan, Akmal
Jurnal Farmasi Andalas Vol 1, No 1 (2013)
Publisher : Jurnal Farmasi Andalas

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Abstract

The in vitro biodegradation testing of plastic of the mixture of polystyrene (PS) and poly (3-hydroxybutirate-co-3-hydroxyvalerat) [P(3HB-ko-3HV)] in soil has been carried out. Plastic film was produced by using blending technique and followed by solved casting at various composition. The biodegradation testing was conduted by using soil burial method. Rseult showed that the increasing of component [P(3HB-ko-3HV)] in the mixture of plastic film was also increase the biodegradation rate of plastic film in the soil. At the composition 100:0, 95:5, 90:10 and 85:15 of plastic film in 5 weeks burial was found weigh remaining of plastic were of 99.67; 95.71; 95.03; 94.13% w/w respectively. It is also observed that the amount of bacteria in the soil were of 2.57 x 106 colonies/g.
Kajian Biodegradasi Filem Plastik Campuran Polistiren Dengan Poli (3-Hidroksibutirat) Dalam Tanah Octaviani, Melzi; Zaini, Erizal; Djamaan, Akmal
Jurnal Farmasi Andalas Vol 1, No 1 (2013)
Publisher : Jurnal Farmasi Andalas

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Abstract

The degradation of a plastic film containing polymer synthetic polystyrene (PS) and biopolymer poly(3-hydroxybutyrate) [P(3HB)] in soil has been carried out based on soil burial test. Result showed that the amount of P(3HB) in plastic film containing PS and P(3HB) influence the degradation rate of plastic film. Rate degradation measured use linear regression equality and parameter is indicated by the slope (k), degradation time 50% (t 50%), and degradation time 95% (t 95%). Degradation plastic film which occurred in soil with ratio PS/P(3HB) 85:15 was k = 0.90 %/week, t 50% = 55.13 weeks and t 95% = 105.29 weeks, followed by PS/P(3HB) 90:10 and PS/P(3HB) 95:15. In contrast, plastic film which made from pure PS (100:0) occurred slow with slope value (k) = 0.14 %/week, t 50% = 345.07 weeks, and t 95% = 655.63 weeks. Result of SEM test showed that damage occurred and erosion at surface of plastic film as long as observation time in various environment condition. 
UJI BIODEGRADASI FILEM PLASTIK CAMPURAN POLISTIREN DENGAN POLI(3 HIDROKSIBUTIRAT-KO-3-HIDROKSIVALERAT) DALAM LUMPUR Dewi, Asiska Permata; Octaviani, Melzi; Rustini, Rustini; Zaini, Erizal; Djamaan, Akmal
Jurnal Sains dan Teknologi Farmasi Vol 17, No 1 (2012)
Publisher : Universitas Andalas

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Abstract

An assay of biodegradation of plastic film combination of polystyrene (PS) and poli (3-hydroxy butyrate-ko-3-hydroxyvalerate) [P(3HB-ko-3HV)] has been conducted. The assay was done by using soil burial test method. The plastic film was made by blending technique of various composition of PS/P(3HB-ko-3HV) in to the mud. The remaining weight of plastic film was determined gravimentically time intervals 1,2,3,4 and 5 weeks of burial. Result showed that the P(3HB-ko-3HV) had an influence on the degradation rate of plastic film. The biodegradation rate increased with an increase in P(3HB-ko-3HV) content in the mixture. The rate was derived from linear regression equation and parameters such as biodegradation rate constant (k), t 50 % and t 95% were obtained. It was found that for combination of  PS/P(3HB-ko-3HV) 95:5 k= 1,26% b/b per week , t 50 % = 39,07 weeks and t 95 % = 74,783 week for the mixture of PS/P(3HB-ko-3HV) 90:10  k = 1,604 % b/b per week, t 50 % = 30,57 week and t 95 % = 58,62 week. For the mixture of PS/P(3HB-ko-3HV), 85:15 k = 2,663 % b/b per week, t 50 % = 17,95 week and t 95 % = 34,85 week. While those of pure PS plastic film k = 0,24 % b/b per week, t 50 % = 201,85 week and t 95 % = 354,55 week which indicated a very slow biodegradation. Analysis by SEM showed that the surface of plastic film was eroded and damaged during the burial. The amount of bacterial colony per 1 gram of mud was 2,31x107.
Biosynthesis of a biopolymer poly(3-hydroxybutyrate) from a mixture of palm oil and 2-butanol as carbon sources Djamaan, Akmal
INDONESIAN JOURNAL OF PHARMACY Vol 22 No 4, 2011
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (448.566 KB) | DOI: 10.14499/indonesianjpharm0iss0pp315-322

Abstract

Polyhydroxybutyrate  [P(3HB)]  are  synthesized  as  carbon  and  energy reserve materials by many types of microorganisms under certain environmental condition. These biosynthetic polyesters have much received attention as they can  be  considered  to  be  a  source  for  developing  novel  biodegradable  plastic materials for pharmaceutical, medical and biodegradable packages industries. In this case,  Erwiniasp. USMI-20, a locally soil isolated microorganism has been found  to accumulate  P(3HB)  in its  cells  during  growth  on  mineral-media  with  a mixture of palm oil and 2-butanol as carbon source. Fermentation process was conducted  through  a  feedbatch  cultivation  under  aerobic  condition  at  pH  7.0, incubation temperature 30 oC, and agitation rate of 200 rpm for 48 hours. The characterization of the  polymer production  was based  on  cell growth  (biomass) and  polymer  content  detected  by  a  gas  chromatography  methode.  Result showed  that  from  a  mixture  of palm  oil:2-butanol  (4.62g/L+0.89g/L) produced P(3HB) of 50.86 %w/w with biomass of 5.82g/L; a mixture of palm oil:2-butanol (4.62g/L+1.65g/L) produced  P(3HB)  of 57,77%  w/w  with  biomas  of 6.01g/L,  a mixture  of  palm  oil:2-butanol  (4.62g/L+2.48g/L)  produced  P(3HB)  of  55.85%w/w with  biomass  of  6.57g/L,   a  mixture  of palm  oil:2-butanol (4.62g/L+3.29 g/L) produced P(3HB) of 56.37% w/w with biomass of 6.67g/L and a mixture of palm  oil:2-butanol  (4.62g/L+4.12g/L)  produced  P(3HB)  of  47.70%  w/w  with biomass of 6.33g/LKey words:biopolymer, poly(3-hydroxybutyrate), palm oil, and n-butanol.
Optimasi Proses Produksi Bioplastik Poli (3-Hidroksibutirat) dengan Bakteri Bacillus Sp Faac 20801 Menggunakan Bahan Dasar Jerami Padi Secara Fermentasi Krisyanella, Krisyanella; Djamaan, Akmal; Aulia, Witra
Jurnal Sains dan Teknologi Farmasi Vol 17 No 1 (2012)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

Optimization of a production of a bioplastic poly (3 - hidroxybutirat) (P(3HB) by fermentation using Bacillus sp FAAC 20801 bacteria and rice straw as carbon source has been carried out. Detection of P(3HB) was done using gas chromatography. The highest glucose level obtain by using H2SO4 5% for hydrolisis. 46,800 mg straw (glucose concentration 200 mg/ml) were obtained 5,379 mg biomass and 0.058 mg P(3HB) ; from 83,400 mg rice straw (glucose concentration 400 mg/ml) were obtained 5,011 mg biomass and 0.124 mg P(3HB) ; from 142,800 mg rice straw (glucose concentration 600 mg/ml) were obtained 3,992 mg biomass and 2.309 mg P(3HB). 
Kajian Biodegradasi Filem Plastik Campuran Polimer Sintetik dengan Biopolimer dalam Larutan Air Octaviani, Melzi; Dewi, Asiska Permata; Boestari, Agusri; Zaini, Erizal; Djamaan, Akmal
Jurnal Sains dan Teknologi Farmasi Vol 17 No 1 (2012)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

A study on degradation of plastic film of the mixture of polystyrene sintetic polymers (PS) with poli(3-hidroxyibutirat) [P(3HB)] dan poli(3-hidroksibutirat-ko-3-hidroxyvalerat) [P(3HB-ko-3HV)] biopolymers in-vitro and in-vivo has been done. The assay was done by immersion test method in aquadest, river water at various pH of 4,6,8, and 10 respectively. Degradation rate was determined by linear regression with parameters including : t 50%, t 95% and rate constant (k). Degradation rate of plastic film of 1 PS/P(3HB) 95:5 at pH 6 was the fastest with k = 0,79 % week, t 50 % = 63,06 week and t 95 % = 119,84 week, followed by PS/P(3HB) 90 : 10 with k = 1,22 % / week, t 50 % = 41,25 week and t 95 % = 78,21 week and PS/P(3HB) 80 : 20 with k = 3,16 % week, t 50 % = 15,81 week and t 95 % = 30,05 week while pure PS plastic film (100 : 0 ) did not degraded at all. The degradation rate of a mixture of plastic film in river water, PS/P(3HB-ko-3HV) 95:5 showed k= 0,64 % week, t 50 % = 82,63 week and t 95 % = 157,17 week, PS/P(3HB-ko-3HV) 90:10 with k = 0,69 % week, t 50 % = 72,16 week and t 95 % = 137,4 week ; PS/P(3HB-ko-3HV) 85:15 with k = 0,74 %/week, t 50% = 66,79 week and t 95% = 127,32 week, while the pure PS plastic film (100:0) did not degrade.
Analisis Faktor-Faktor Yang Mempengaruhi Kepuasan Kerja Apoteker Yang Bekerja di Apotek di Kota Padang Djamaan, Akmal; Syahrul, Laura; Bakhtra, Dwi Dinni Aulia
Jurnal Sains dan Teknologi Farmasi Vol 18 No 1 (2013)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

Humans resources must be evaluated as a key factor in an organizations success. Humans resource organization has a wide range of needs. Job satisfaction is a reflection of the employees attitude towards the overall feeling of the work, it consists of various aspects. Job satisfaction can improve service quality and increase employee satisfaction. This was a descriptive study about pharmacists who work at a pharmacy in Padang city as much as 50 respondent. There are six variables that influence job satisfaction of pharmacists: working conditions, salary, promotion, fair treatment, job security, relationships with co-workers and the relationship with the leader. Results showed that the pharmacists working at pharmacies in Padang was just quite satisfied with the work. There was a variable relationship between co-workers and the job satisfaction of the respondents in the amount of 76.32%. Total achievements of the respondents to the relationship with the fair treatment of 75.76 %, 75.68% working conditions, relations with the leaders of 73.92%, 72.79% salary and promotion. Variables of job security less the total respondents 59.80% achievement . Differences in demographic factors also affect the job satisfaction of the respondents. Job satisfaction of male respondents are influenced by working conditions, while the female respondents are affected by fair treatment and relationships with co-workers. Respondents who have a service life over 5 years shows that work satisfaction is strongly influenced by the variable of fair treatment while his tenure of 1 to 5 years are affected by working conditions. Respondents who have over 30 years of age are affected by work satisfaction and working conditions for the age 24 to 30 years of work satisfaction is strongly influenced by fair treatment.
Uji Biodegradasi Filem Plastik Campuran Polistiren dengan Poli(3 Hidroksibutirat-Ko-3-Hidroksivalerat) dalam Lumpur Dewi, Asiska Permata; Octaviani, Melzi; Rustini, Rustini; Zaini, Erizal; Djamaan, Akmal
Jurnal Sains dan Teknologi Farmasi Vol 17 No 1 (2012)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

An assay of biodegradation of plastic film combination of polystyrene (PS) and poli (3-hydroxy butyrate-ko-3-hydroxyvalerate) [P(3HB-ko-3HV)] has been conducted. The assay was done by using soil burial test method. The plastic film was made by blending technique of various composition of PS/P(3HB-ko-3HV) in to the mud. The remaining weight of plastic film was determined gravimentically time intervals 1,2,3,4 and 5 weeks of burial. Result showed that the P(3HB-ko-3HV) had an influence on the degradation rate of plastic film. The biodegradation rate increased with an increase in P(3HB-ko-3HV) content in the mixture. The rate was derived from linear regression equation and parameters such as biodegradation rate constant (k), t 50 % and t 95% were obtained. It was found that for combination of  PS/P(3HB-ko-3HV) 95:5 k= 1,26% b/b per week , t 50 % = 39,07 weeks and t 95 % = 74,783 week for the mixture of PS/P(3HB-ko-3HV) 90:10  k = 1,604 % b/b per week, t 50 % = 30,57 week and t 95 % = 58,62 week. For the mixture of PS/P(3HB-ko-3HV), 85:15 k = 2,663 % b/b per week, t 50 % = 17,95 week and t 95 % = 34,85 week. While those of pure PS plastic film k = 0,24 % b/b per week, t 50 % = 201,85 week and t 95 % = 354,55 week which indicated a very slow biodegradation. Analysis by SEM showed that the surface of plastic film was eroded and damaged during the burial. The amount of bacterial colony per 1 gram of mud was 2,31x107.
Isolation of Secondary Metabolite A. niger “In-Habiting” Queen M. gilvus Hagen.’s Nest Alen, Yohannes; Melati, Atika; Sarina, Gemmy; Djamaan, Akmal
Indonesian Journal of Pharmaceutical Science and Technology Vol 5, No 2 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (524.816 KB) | DOI: 10.15416/ijpst.v5i2.15364

Abstract

Aspergillus niger is pathogen fungi that can live in various locations and can live contiguous with many hosts, one of them is queen termite’s nest. The aims of the study were to isolated the secondary metabilite of A.niger. Extraction proccess of secondary metabolite compounds was carried out by maceration method using methanol solvent. Based on that proccess, methanol extract was be yield 4,32% sample weight. Fractination proccess was carried out in the separating funnel using ethyl acetate solvent, which ethyl acetate fraction was be yield 14.39% methanol extract. Separation of the compounds was carried out by column chromatography method using n-hexane and ethyl asetate eluents. Purification of the compounds were done by recrystallization method using n-hexane and ethyl asetate. Two secondary metabolite compounds were successfully isolated from ethyl acetate fraction of the methanolic extract of fungus A. niger “In-Habiting” queen termite’s nest M. gilvus Hagen. Based on organoleptic examination, the compound signed AM-12-22-01 is 35 mg, white needle crystals, melting point 151-153 oC. While, the AM-12-60-01* is 15 mg, white needle crystals, melting point 91-93 oC. Based on the chemical analysis, thin layer chromatography, ultraviolet and infrared spectra data it was identified that AM-12-22-01 and AM-12-60-01 were a phenolic compounds.Key words: isolation, A. niger, In-Habiting, M. gilvus Hagen.
TLC Profile and Activity Test of Secondary Metabolites Aspergillus flavus “In-Habiting” Queen Termite’s Nest Macrotermes gilvus on Enriched Media Alen, Yohannes; Amelia, Rezki; Djamaan, Akmal
Indonesian Journal of Pharmaceutical Science and Technology Vol 5, No 1 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (589.946 KB) | DOI: 10.24198/ijpst.v5i1.14644

Abstract

Antibiotic are secondary metabolites yielded by microbe especially fungus. Previous research succesfull screened four kinds of fungus that live in termites queen’s nest, one of them was Aspergillus flavus. Furthermore, Alen et al (2016g) states that this fungus last to produce metabolite compounds on SDA media which only exist in first and second  subculture extract, omit gradually for the next culture. It was presumed happen caused a different habitat to grow. So it is necessary to enrich the media with queen termite nest to get back the initial metabolites. The enrichment was done using four different media concentrations (0.25; 0,50; 0.75 and 1 grams of nest/mL media). The results show that enrichment of 1 gram of nest/mL media provides the most optimum fungus growht. The third subculture of Aspergillus flavus is cultured on enriched media which will become the fourth subculture, this fungus cultured until tenth subculture, do extraction and   fracination to each culture. Based on TLC profile analysis, the initial metabolite not yet formed until tenth subculture, but forms six new stain terpenoid compounds.  The result of  columns chromatography obtained 10 sub-faction. Activity test was done by diffusion method to 12  test bacteria and 3 test fungus. Spot 2,5,6 (Rf 0.84; 0,36; 0,26) inhibit the growth of Pseudomonas aeruginosa ATCC 27853, spot 3,4 (Rf 0.74; 0,52) inhibit the growth of Micrococcus luteus ATCC 10240. The use of enriched media affect formation of  secondary metabolites Aspergillus flavus.  Keyword : Secondary metabolites, Aspergillus flavus, Macrotermes gilvus Hagen., Enriched media, TLC Profiles, Activity Assay
Co-Authors Agusri Boestari Andani Eka Putra Anthoni Agustien Arfiandi Arfiandi Asia Asia Asiska Permata Dewi Asiska Permata Dewi Asiska Permatadewi Atika Melati Bakhtra, Dwi Dinni Aulia Bilqis Nurganiyu Densi Selpia Sopianti Densi Selpia Sopianti Desma Yuni Dewi Gulyla Hari Dian Handayani Dini Hanifa Edtyva Monicha Elmi Sariani Hasibuan Erizal Zaini Fatimah Saidah Gustina ' Inayati Rahmi irfan mustafa Irfan Mustafa Krisyanella Krisyanella Krisyanella Krisyanella Kustiasih Lestari Laura Syahrul Lola Alviche Mahrani Napitupulu Majid, Mohammed Isa Abdul Maria Ulfa Marlina . Melati, Atika Melzi Octaviani Mimi Susanti Mohamed Isa Abd. Majid Mohd. Azizan Mohd. Noor Muslim Suardi Musyirna Rahmah Nst Netty Suharti Netty Suharty Noor, Mohd. Azizan Mohd. Novesar Jamarun Refilda Refilda Rendowaty, Agnes Rezki Amelia Rezki Amelia Rina Wahyuni Rini Agustin Rusmana Wijaya Setia Ningrat Rustini Rustini Rustini Rustini Salman - Salman - Sarina, Gemmy Sri Elfina Syamsuardi Syamsuardi Syukri Arief Syukria Ikhsan Zam Syukria Ikhsan Zam Witra Aulia Witra Aulia Yohannes Alen Yufri Aldi Yutra Noka