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All Journal Majalah Kedokteran Bandung Jurnal Kesehatan Andalas Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun Journal of Midwifery Jurnal Respirologi Indonesia Majalah Kedokteran Andalas International Islamic Medical Journal Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Jurnal Ilmu Kesehatan Indonesia
Aisyah Elliyanti
Nuclear Medicine Division, Faculty Of Medicine, Universitas Andalas
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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The Enhancement of COVID-19 Severity on Coagulation Markers: a Cross-sectional Study in West Sumatra, Indonesia Ika Kurnia Febrianti; Andani Eka Putra; Raveinal Raveinal; Aisyah Elliyanti
Majalah Kedokteran Andalas Vol 46, No 10 (2024): Online May 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i10.p1712-1723.2024

Abstract

Objective: This study aimed to determine the description of the coagulation marker and how it implicates COVID-19 patients based on clinical outcomes in the form of enhancement severity and death. Method: The subjects were collected from patients with positive COVID-19 RT-PCR with medical records including demographic data, and laboratory results such as hemoglobin, hematocrit, leukocytes, platelets, coagulation markers (D-dimer, PT, and APTT), and patients outcomes post-treatment. Statistical analysis is performed by using chi-square and Mann-Whitney tests were considered statistically difference level of significant between variables. Result: The COVID-19 patients is classified into mild group with 27 subjects  (44.2%) and moderate-severe group 34 subjects (55.8%). Leukocytes, D-dimer, and PT levels significantly differed between mild and moderate-severe groups. All coagulation markers had a symptomatic effect on Covid-19 patients, increased D-dimer and prolonged prothrombin time in adult COVID-19 patients tend to be followed by the enhancement of severe symptoms and death
Co-Authors Afriwardi Afriwardi Andani Eka Putra Arina Widya Murni Arnelis Arnelis Arni Amir Ashal, Taufik Aswiyanti Asri Daan Khambri Dewi Anggraini Dian Pertiwi Dian Pertiwi Dodi Safari Elizabeth Bahar Elmatris Sy Eryati Darwin Eti Yerizel Eti Yerizel Faiz Chalidzar Fika Anggraini Fitri Wahyu Febriwani Hendriati, Hendriati Herlambang Herlambang Husnil Wardiyah Ika Kurnia Febrianti Ilmiati Ilmiati Indra Yovi Iskandar Iskandar Johan S. Masjhur, Johan S. Julizar Julizar Julizar Julizar Katrin Monika Lili Irawati Meidrin Joni Miftah Irrahmah Miftah Irramah Mohamad Reza Noormartany . Nora Harminarti Noza Hilbertina Nur Afrainin Syah Nurhajjah, Sitti Rahmad Syawqi Rahmat Syawqi RAVEINAL RAVEINAL Rina Gustia S Setiyowati Sabar Hutabarat Siti Nurhajjah Sorayya A'dilah Putri Suminta RS, Teresia Syaiful Azmi Tenny Putri Wikayani, Tenny Putri Thira Fasril Tri Hanggono Achmad Vanesya Zahrani Shapira VY Susilo Yose Ramda Ilhami Yose Ramda Ilhsmi Yulia Iriani, Yulia Yulia Kurniawati Yulia Kurniawati Yulistini, Yulistini Zelly Dia Rofinda Zelly Dia Rofinda Zulfa Nur Hanifah