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Journal : Journal of Maternal and Child Health

Meta-Analysis the Effect of Hormonal Contraception on Sexual Disfunction in Injection and Oral Contraceptive Acceptors Sumiyati, Sumiyati; Budihastuti, Uki Retno; Murti, Bhisma
Journal of Maternal and Child Health Vol. 7 No. 6 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (34.844 KB) | DOI: 10.26911/thejmch.2022.07.06.11

Abstract

Background: One of the factors that cause sexual dysfunction is the use of hormonal con­tra­ception. The hormone progesterone in contraceptives functions to thicken cervical mucus. In addi­tion, the hormone progesterone also facilitates the conversion of carbohydrates into fat so that one of the side effects is causing body weight to increase and reducing sexual arousal which causes an effect on sexual desire. This study aimed to analyze the effect of the use of injectable hor­monal contraception and pills on the incidence of sexual dysfunction using a meta-analysis study. Subjects and Method: This study is a systematic review and meta-analysis using the PRISMA flowchart diagram. The process of searching for articles was carried out with a range of 2011-2022 in the Google Scholar, PubMed, Science Direct, Researchgate and Springerlink databases. The key­words used in the article search are “hormonal contraceptive” AND “oral contraception” OR “pills contraceptive” AND “injectable contraceptive” AND “sexual dysfunction” AND “cross-section­al”. The inclusion criteria are full text articles with cross-sectional study design, articles using English, multivariate analysis with Adjusted Odds Ratio. Articles that met the requirements were analyzed using the RevMan 5.3 application. Results: A total of 14 articles with a cross-sectional study design originating from Iran, Indonesia, Malaysia, Ethiopia, Egypt, Washington, Sweden and Polan were meta-analyzed in this study. A meta-analysis of 7 articles showed that there was an effect of using injectable hormonal con­tra­cep­tion on the incidence of sexual dysfunction 1.66 times compared to those not using injectable contraception, but this was not statistically significant (aOR= 1.66; 95% CI= 0.65 to 4.26; p= 0.290). Meanwhile, 7 articles showed that women using oral contraceptives had a 1.42 times risk of experiencing sexual dysfunction compared to not using oral contraceptives and this was sta­tis­tically significant (95% CI= 1.04 to 1.92; aOR= 1.42; p= 0.030). Conclusion: Injectable hormonal contraceptives show that there is an effect on the incidence of sexual dysfunction, but statistically this relationship is not significant. Hormonal contraceptive pills showed an effect on the incidence of sexual dysfunction and was statistically significant.  Keywords: sexual dysfunction, injectable contraceptives, oral contraceptives, meta-analysis. Correspondence:Sumiyati. Master’s Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: mia.azizi.ma@gmail.com. Mobile: +6282282246211.
Co-Authors A.A. Ketut Agung Cahyawan W Abdullah, Moch. Rizal Agung, Sumarno Aini, Fajaria Nur Ajeng Ayu Milanti Akse, Ellin Vioni Allail, Rifal Anak Agung Gede Sugianthara Anita Widiastuti Arry Irawan Aviantara, Muhammad Putra Bagoes Widjanarko Bambang Widjajanta, Bambang Barnas, Benny Baskara, Chedi Cakra Bhisma Murti Cecep Kusmana Daryati, Daryati Daryati, Daryati Deni Mulyana Dessy Sunarsi Dian Imanina Burhany Djaswadi Dasuki Eddy Noviana Eded Tarmedi, Eded Euis Soliha Fadllillah, Nida Faisal Akbar, Muhammad Fatmawati, Adelia Rizky Girang Razati, Girang Gunawan, Muhammad Taufik S Gustirani, Indri Hastuti Hastuti Hazma Hazma Hermawan Lumba, Hermawan Hesti Kurniasih, Hesti Hunaepi, Hunaepi Iskandar, Dede Nur Ita Susanti Ita Susanti ita susanti Jiana, Sri Jogiyanto Hartono Juliandiny, Tiffany K Y Margiati, K Y Kamal, Nasrul Khairul Katsirin Krisna Yudha B Kunlestiowati Kunlestiowati Linayanti Linayanti M. Syamsul Hidayat M. Yunus Maulana Mahri, Nadya Makarim, Helwiyah Makarim, Helwiyah Masharyono Masharyono Maulana, Farhan Mia Rosmiati Muhammad Jiddan Zamhar Muhammad Umar Mai Mukhamad Najib Murdiyanto, Lilik Nabilah Febriyane Prasetyo Widodo Nazdia, Lusiana Arsyah Neneng Dahtiah Nurdini, Atin Nurfitrianti, Marisa Nurjannah Nurjannah Ova Emilia Pramana, Reynaldi Rafi Pratiwi, Ngindi Fadhilah Puji Hastuti Putri Rahmawati Putri, Nabila Farahdila R. Sapto Hendri Boedi Soesatyo R. Siti Pupu Fauziah Rachmad Imbang Trittjahjono Rahmiatul Aula Ramdhan, Jovin Ganda Rd. Dian Herdiana Utama, Rd. Dian Herdiana Riauli S. Hutapea Ridwan Purnama, Ridwan Rinaldi, R Robissalami, Devi Ryan Rahmadi, Ryan Sari, Whidya Udaya Senen, Syamsul H. Sholihati Amalia Silmi Hibban Falah, Silmi Hibban Sri Widadi Suhardi Marli Sulistia Suwondo Sundawa, Irfan Noor Syafarina, Shenny Syafwandi, Syafwandi Syahrilfuddin Syahrilfuddin, Syahrilfuddin Syamsul Hadi Senen, Syamsul Hadi Syarief, Mochamad Edman Tedy Purwanto, Tedy Uki Retno Budihastuti Wardhana, R M Doni HA Wastukurning Purbandini Widjadjanta, Bambang Widjajanta, Bambang - Winarso, Septerina Purwandani Yanti Rufaedah Yuherman Yuherman Yuli Nawangsasi Yuliadi, Hendri Yusnarti, Mulya Zulfikar, Ryandi