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Nurul Hidayati
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Journal : Jurnal Ilmiah Manuntung

 1 
PENGARUH KEMASAN TERHADAP AKTIVITAS ANTI BAKTERI SUSPENSI ERITROMISIN SETELAH PENYINARAN DENGAN SINAR MATAHARI LANGSUNG Hidayati, Nurul
Jurnal Ilmiah Manuntung Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.592 KB) | DOI: 10.51352/jim.v2i1.43

Abstract

Erythromycin is a type of antibiotic medication. The drug is unstable when in the water because it can undergo hydrolysis process. Fortunately, it can be prevented by making dry syrup dosage form. In addition to hydrolysis, erythromycin can also have photolysis. For preventing the reaction, it can be done by packing the medication in an opaque and tightly closed container. This research was conducted to determine the effect of packaging on the stability of erythromycin suspension that has been exposed to direct sunlight within a period. The research was done by exposing erythromycin suspension, which was packed with three kinds of color packaging namely brown, translucent, and opaque, for 30 minutes, 60 minutes, 90 minutes and 120 minutes, then continued by a microbiological test with a diffusion method to determine the activity of erythromycin against Staphylococcus Aureus. The results of the research showed the existence of diameter of barrier areas around the spots that were given a test solution. It means that the test solution has antibiotic activity against bacteria. Preparations packaged in brown color have higher inhibition when compared with the opaque and translucent. It shows that the erythromycin suspension packaged in brown colors was more efficient in stabilizing the preparation
Co-Authors - Sutaryono Adi Indra Pratama Afrilia Wulan Sari Agus Hery Supadmi Irianti AGUS RIYANTO Agus Sarono, Agus Agustina Wulandari Al Kusaeri, Al Kusaeri Alfia Magfirona Amaliah, Riska Ana Sugesti Arfi Syamsun Aristhasari Putri Arum, Fitri Ati Retna Sari Bakar, Resekiani Mas Bakar, Resekiani Mas Bertha Yonata Budi Warsito Cahyo Wibowo Chairil Effendy Chandra Santi Chntia Sari Choiril Hana Mustofa Christanto Syam Dedi Adha Dewi, Kencana Murni Sari Dian Kurniawati Dimyati Dwi Cahyono, Febryan Dwi Harjanto, Dwi Eko Ruddy Cahyadi Emir Al Hasan Enggal Miftahul Jannah Evayanti, Yulistiana Fadhilah, Rindi Anti Nur Faqih Hamami Fathul Djannah Fatiya Juwita Hanum Fatmawati, Elis Fidiana, Fidiana Fithriani Armin Fitriyatul Mahmudah Giffani, Inastuti Retno Giffani, Inastuti Retno Gina Saptiani Gotot Slamet Mulyono Gus Maelan Irfana Hadiyah Hadiyah Hamim Hamim Hapipah Hapipah Hardiansah, Wahyu Harry Soesanto Haryani Haryani Hayatun Nufus Heru Subaris Kasjono I Istomo Ida Rahmah Burhan Ida Zulaeha Idah Hadijah Idha Rahayuningsih Ika Wahyu Purwaningtyas Ike Betria Indrianasari, Neny Tri Istianah Istianah Jamhari Jamhari Junaidi Junaidi Kencana Murni Sari Dewi Khairul Anam Bahrur Kuniyoshi Shimizu Lady Octaviany Iqmi Lestari, Widya Mahfudy, Sofyan Malikah Umar Maslichah, Maslichah Mayta Novaliza Isda Meria Kontesa Mimiek Murrukmihadi Misbahul Munir Mitayani Mochamad Hasyim Moh Tsabit Muhammad Khafid Muthia Cenderadewi, Muthia NISA RACHMANIA MUBARIK Novria Hesti Nur Endah Purwaningsih Pramita Putri Utami Prasetyo, Deni Widyo Putri Susanti Qory Addin Ratna Wulandari Rian aprilianti Riska Yanu Fa’rifah Rista Dwi Permata ROCHMAWATI Rodiyah . Rofiah, Chusnul Rudi Triyono Rusiana, Harlina Putri saifudin zukhri - Saiful Umar Salsabila, Unik Hanifah Sarjito - Sestu Retno Dwi Andayani Shefia Nur Rohmah Siti Anifah Siti Rahmawati Siti Wahyuningsih Siti Ziyadaturrohmah Slamet Budi Prayitno Sri . Handayani Sri Eko Puji Rahayu Sri Handayani Sri Hidayati Syarief Sri Sunarjono Sri Wahyuni Styawan, Anita Agustina Sulistyo Sulistyo Sunyoto Sunyoto Supriyadi Supriyadi Sutaryono Sutaryono - Suyatno Suyatno Syarifah Nur Siregar Syuhada Sufian Tarpin Juandi Tita Tri Antika Pangestuti Triyono, Rudi Tukiran Tukiran Tukiran Tukiran Walid Walid, Walid Windi Kurnia Lestari Yatminiwati, Mimin Yayi Suryo Prabandari Yenita Roza Zaenuri Mastur Ziadatul Munawarah Zilhardi Idris